Patrick Gillard
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View article: Long-Term Prophylactic Treatment Preferences and Willingness to Switch Therapy in Individuals With Hereditary Angioedema
Long-Term Prophylactic Treatment Preferences and Willingness to Switch Therapy in Individuals With Hereditary Angioedema Open
Effectiveness was the main driver of LTP preference; other factors were also important, including convenience. When effectiveness was equivalent, oral administration was preferred over injectable administration. Individuals with HAE were m…
View article: Reductions in medical visits and hospitalizations following berotralstat initiation in patients with hereditary angioedema in the United States
Reductions in medical visits and hospitalizations following berotralstat initiation in patients with hereditary angioedema in the United States Open
Prophylactic treatment of HAE with berotralstat was associated with significant reductions in all-cause HRU, including decreases to angioedema-related and HAE attack-related medical visits, hospitalizations, and administration of on-demand…
View article: Adherence and persistence among patients with hereditary angioedema receiving long-term prophylaxis in the United States
Adherence and persistence among patients with hereditary angioedema receiving long-term prophylaxis in the United States Open
Introduction: Real-world evidence that compares the treatment patterns of targeted long-term prophylaxis (LTP) for hereditary angioedema (HAE), including berotralstat, lanadelumab, and subcutaneous (SC) plasma-derived C1 inhibitor (pdC1-IN…
View article: Healthcare resource utilization and costs among patients with post-stroke spasticity before and after spasticity management including onabotulinumtoxina
Healthcare resource utilization and costs among patients with post-stroke spasticity before and after spasticity management including onabotulinumtoxina Open
Background: Real-world data regarding the impact of onabotulinumtoxinA on healthcare resource utilization and costs for post-stroke spasticity are scarce. Objective: To compare differences in 12-month healthcare resource utilization and co…
View article: Healthcare resource utilization and costs for patients with postoperative atrial fibrillation in the United States
Healthcare resource utilization and costs for patients with postoperative atrial fibrillation in the United States Open
POAF following open-heart surgery poses a significant economic burden up to 1 year postdischarge.
View article: Real-world persistence and costs among patients with chronic migraine treated with onabotulinumtoxinA or calcitonin gene-related peptide monoclonal antibodies
Real-world persistence and costs among patients with chronic migraine treated with onabotulinumtoxinA or calcitonin gene-related peptide monoclonal antibodies Open
BACKGROUND: Chronic migraine (CM) is a common neurologic disorder that imposes substantial burden on payers, patients, and society. Low rates of persistence to oral migraine preventive medications have been previously documented; however, …
View article: Total healthcare cost savings through improved bipolar I disorder identification using the Rapid Mood Screener in patients diagnosed with major depressive disorder
Total healthcare cost savings through improved bipolar I disorder identification using the Rapid Mood Screener in patients diagnosed with major depressive disorder Open
The RMS is a cost-effective tool to identify BP-I in patients who would otherwise be misdiagnosed with MDD. Screening with the RMS resulted in cost-savings over 3 years, with model results remaining robust even with lower prevalence of BP-…
View article: Cost–effectiveness of overactive bladder treatments from a US commercial and payer perspective
Cost–effectiveness of overactive bladder treatments from a US commercial and payer perspective Open
Aim: The cost–effectiveness of treatment options (anticholinergics, β3-adrenoceptor agonists, onabotulinumtoxinA, sacral nerve stimulation and percutaneous tibial stimulation [the latter two including new rechargeable neurostimulators]) fo…
View article: Annual costs among patients with major depressive disorder and the impact of key clinical events
Annual costs among patients with major depressive disorder and the impact of key clinical events Open
BACKGROUND: The economic burden of major depressive disorder (MDD) is substantial and increasing; however, the impact of key clinical events (eg, hospitalization, suicide attempt/ideation, and treatment changes) on health care resource use…
View article: Place of care and costs associated with acute episodes and remission in bipolar I disorder
Place of care and costs associated with acute episodes and remission in bipolar I disorder Open
Most BP-I acute manic/mixed or depressive episodes were treated in the outpatient setting. Episodes with inpatient care were 8-10 times more costly than outpatient-only episodes. Health plans covered most medical costs, but additional pati…
View article: The real-world health resource use and costs of misdiagnosing bipolar I disorder
The real-world health resource use and costs of misdiagnosing bipolar I disorder Open
The prompt and correct diagnosis of BP-I may significantly reduce HRU and costs.
View article: Treatment Patterns Among Patients with Bipolar Disorder in the United States: A Retrospective Claims Database Analysis
Treatment Patterns Among Patients with Bipolar Disorder in the United States: A Retrospective Claims Database Analysis Open
Antidepressants and benzodiazepines were frequently prescribed to treat bipolar disorder despite guidelines recommending against use as frontline therapy. These results highlight the considerable heterogeneity in care and suggest that many…
View article: The Rapid Mood Screener: A Novel and Pragmatic Screener Tool for Bipolar I Disorder
The Rapid Mood Screener: A Novel and Pragmatic Screener Tool for Bipolar I Disorder Open
Introduction Approximately 70% of patients with bipolar disorder (BPD) are initially misdiagnosed, resulting in significantly delayed diagnosis of 7–10 years on average. Misdiagnosis and diagnostic delay adversely affect health outcomes an…
View article: Pathway with single‐dose long‐acting intravenous antibiotic reduces emergency department hospitalizations of patients with skin infections
Pathway with single‐dose long‐acting intravenous antibiotic reduces emergency department hospitalizations of patients with skin infections Open
Objectives Emergency department (ED) patients with serious skin and soft tissue infections (SSTIs) are often hospitalized to receive intravenous (IV) antibiotics. Appropriate patients may avoid admission following a single‐dose, long‐actin…
View article: Health care resource utilization and costs associated with nonadherence and nonpersistence to antidepressants in major depressive disorder
Health care resource utilization and costs associated with nonadherence and nonpersistence to antidepressants in major depressive disorder Open
BACKGROUND: Nonadherence and nonpersistence to antidepressants in major depressive disorder (MDD) are common and associated with poor clinical and functional outcomes and increased health care resource utilization (HCRU) and costs. However…
View article: The Rapid Mood Screener (RMS): a novel and pragmatic screener for bipolar I disorder
The Rapid Mood Screener (RMS): a novel and pragmatic screener for bipolar I disorder Open
Depressive episodes and symptoms of bipolar I disorder are commonly misdiagnosed as major depressive disorder (MDD) in primary care. The novel and pragmatic Rapid Mood Screener (RMS) was developed to screen for manic symptoms and bipolar I…
View article: Contemporary treatment utilization among women diagnosed with symptomatic uterine fibroids in the United States
Contemporary treatment utilization among women diagnosed with symptomatic uterine fibroids in the United States Open
Background This study evaluated treatment patterns among women diagnosed with symptomatic uterine fibroids (UF) in the United States. Data were retrospectively extracted from the IBM Watson Health MarketScan® Commercial Claims and Encounte…
View article: Poster Session I
Poster Session I Open
Introduction: Depressive episodes/symptoms of bipolar I disorder (BPD-I) are commonly misdiagnosed as major depressive disorder (MDD).We developed a brief, self-rated, pragmatic tool that screens for manic symptoms and identifies BPD-I ris…
View article: Direct Costs Incurred Among Women Undergoing Surgical Procedures to Treat Uterine Fibroids
Direct Costs Incurred Among Women Undergoing Surgical Procedures to Treat Uterine Fibroids Open
This study was sponsored by Allergan, Dublin, Ireland. Allergan played a role in the conduct, analysis, interpretation, writing of the report, and decision to publish this study. Harrington and Ye are employees of Allergan. Stafkey-Mailey,…
View article: Dalbavancin Reduces Hospital Stay and Improves Productivity for Patients with Acute Bacterial Skin and Skin Structure Infections: The ENHANCE Trial
Dalbavancin Reduces Hospital Stay and Improves Productivity for Patients with Acute Bacterial Skin and Skin Structure Infections: The ENHANCE Trial Open
Allergan plc.
View article: 456. Dalbavancin, a Long-Acting Lipoglycopeptide Antimicrobial Agent, Reduces Length of Stay and Improves Patient Work Productivity in a Hospital Critical Pathway for Acute Bacterial Skin and Skin Structure Infections (ABSSSI)—the ENHANCE ABSSSI Trial
456. Dalbavancin, a Long-Acting Lipoglycopeptide Antimicrobial Agent, Reduces Length of Stay and Improves Patient Work Productivity in a Hospital Critical Pathway for Acute Bacterial Skin and Skin Structure Infections (ABSSSI)—the ENHANCE ABSSSI Trial Open
Background Prolonged admissions for acute bacterial skin and skin structure infections (ABSSSI) present an opportunity to improve efficiency and quality of care. A primary reason for admission for ABSSSI is to receive intravenous (IV) anti…
View article: Health-Related Quality of Life With Ulipristal Acetate for Treatment of Uterine Leiomyomas
Health-Related Quality of Life With Ulipristal Acetate for Treatment of Uterine Leiomyomas Open
OBJECTIVE: To investigate effects of ulipristal acetate on health-related quality of life (QOL) and symptom severity in women with symptomatic uterine leiomyomas and abnormal uterine bleeding. METHODS: Women were randomized to ulipristal (…
View article: Single-dose dalbavancin and patient satisfaction in an outpatient setting in the treatment of acute bacterial skin and skin structure infections
Single-dose dalbavancin and patient satisfaction in an outpatient setting in the treatment of acute bacterial skin and skin structure infections Open
Single-dose dalbavancin is an effective treatment option for outpatients with ABSSSI and is associated with a high degree of patient treatment satisfaction and convenience.
View article: Additional file 1: of Development of a bedside tool to predict the probability of drug-resistant pathogens among hospitalized adult patients with gram-negative infections
Additional file 1: of Development of a bedside tool to predict the probability of drug-resistant pathogens among hospitalized adult patients with gram-negative infections Open
contains the Clinical Bedside Tool. (XLSM 162 kb)
View article: A systematic review of the association between delayed appropriate therapy and mortality among patients hospitalized with infections due to Klebsiella pneumoniae or Escherichia coli: how long is too long?
A systematic review of the association between delayed appropriate therapy and mortality among patients hospitalized with infections due to Klebsiella pneumoniae or Escherichia coli: how long is too long? Open
Our findings suggest there is a need to shift current treatment practices away from antibiotic escalation strategies that contribute to delayed appropriate therapy and toward early, relatively aggressive and comprehensive, antibiotic thera…
View article: Impact of Delayed Appropriate Antibiotic Therapy on Patient Outcomes by Antibiotic Resistance Status From Serious Gram-negative Bacterial Infections
Impact of Delayed Appropriate Antibiotic Therapy on Patient Outcomes by Antibiotic Resistance Status From Serious Gram-negative Bacterial Infections Open
Our results suggest that outcomes in patients with GNB infections, regardless of resistance status, significantly improve if timely appropriate therapy can be provided.