Patrick Govender
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View article: Redox-responsive peptidosomes: A promising strategy for expanding vancomycin antibiotic spectrum and efficacy against resistant bacterial infections
Redox-responsive peptidosomes: A promising strategy for expanding vancomycin antibiotic spectrum and efficacy against resistant bacterial infections Open
Background: Infectious diseases pose a significant global burden, impacting healthcare systems and economies worldwide, exacerbated by the rise of drug resistance. Research is thus focusing on alternative treatment strategies less prone to…
View article: Cover Image
Cover Image Open
Chemical Biology & Drug Design is a peer-reviewed scientific journal that is dedicated to the advancement of innovative science, technology and medicine with a focus on the multidisciplinary fields of chemical biology and drug design.It is…
View article: A novel MALDI-TOF mass spectrometry sample preparation strategy for improved proteomic biotyping of clinically significant Mycobacteria
A novel MALDI-TOF mass spectrometry sample preparation strategy for improved proteomic biotyping of clinically significant Mycobacteria Open
A precise routine method is essential for the rapid identification of pathogenic mycobacterial species to support our publicly maintained health care management systems to efficiently treat and control and emerging tuberculosis pandemic th…
View article: Improved Production of HIV-1 Subtype C Protease from Transgenic E. Coli
Improved Production of HIV-1 Subtype C Protease from Transgenic E. Coli Open
Background: Human Immunodeficiency Virus 1 (HIV-1) subtype C is responsible for the majority of infections of patients in Southern Africa. The HIV protease is a primary target for the development of highly efficient anti-retroviral pharmac…
View article: Improved production of HIV-1 subtype C protease from transgenic E coli
Improved production of HIV-1 subtype C protease from transgenic E coli Open
The data set belongs to study carried out by Uraisha Ramlucken at Department of Biochemistry, University of KwaZulu-Natal, Durban, South Africa. This study was made possible through financial support from the National Research Foundation.
View article: Improved production of HIV-1 subtype C protease from transgenic E coli
Improved production of HIV-1 subtype C protease from transgenic E coli Open
The data set belongs to study carried out by Uraisha Ramlucken at Department of Biochemistry, University of KwaZulu-Natal, Durban, South Africa. This study was made possible through financial support from the National Research Foundation.
View article: Antibacterial Properties of Organosulfur Compounds of Garlic (Allium sativum)
Antibacterial Properties of Organosulfur Compounds of Garlic (Allium sativum) Open
Garlic ( Allium sativum ), a popular food spice and flavoring agent, has also been used traditionally to treat various ailments especially bacterial infections for centuries in various cultures around the world. The principal phytochemical…
View article: Synthesis, Characterization and In Vitro Antibacterial Evaluation of Pyrenacantha grandiflora Conjugated Silver Nanoparticles
Synthesis, Characterization and In Vitro Antibacterial Evaluation of Pyrenacantha grandiflora Conjugated Silver Nanoparticles Open
In the present study, silver nanoparticles (AgNPs) were synthesized using both the chemical and biological methods and conjugated with Pyrenacantha grandiflora extracts. These were then characterized and evaluated for antimicrobial activit…
View article: Green Synthesis of Metal Nanoparticles for Antimicrobial Activity
Green Synthesis of Metal Nanoparticles for Antimicrobial Activity Open
The development and extensive spread of multi-drug resistant bacteria are considered as a major public health concern. Failures to control severe infections due to antibiotic resistance have augmented healthcare costs as well as patient mo…
View article: Phytochemical composition and biological investigation of Trichilia emetica Vahl. seed extracts
Phytochemical composition and biological investigation of Trichilia emetica Vahl. seed extracts Open
The current study investigated the phytochemical analysis, chemical composition, antioxidant, cytotoxic and antifungal activity of Trichilia emetica seed extracts. Preliminary phytochemical screening and quantification were realized by GC-…
View article: Improved production of HIV-1 subtype C protease from transgenic E coli
Improved production of HIV-1 subtype C protease from transgenic E coli Open
The data set belongs to study carried out by Uraisha Ramlucken at Department of Biochemistry, University of KwaZulu-Natal, Durban, South Africa
View article: Physico-chemical, antimicrobial and anticancer properties of silver nanoparticles synthesised from organ-specific extracts of Bidens pilosa L.
Physico-chemical, antimicrobial and anticancer properties of silver nanoparticles synthesised from organ-specific extracts of Bidens pilosa L. Open
There is an increasing commercial demand for nanoparticles synthesis by green as opposed to chemical methods, given the toxicity and contamination risks associated with the latter. This study compared the physico-chemical, antimicrobial an…
View article: IN VITRO ANTIOXYDANT ACTIVITY AND TOTAL PHENOLIC CONTENT OF EXTRACTS FROM THE ENDEMIC ARGANIA SPINOSA (L.) SKEELS FROM ALGERIAN SAHARA
IN VITRO ANTIOXYDANT ACTIVITY AND TOTAL PHENOLIC CONTENT OF EXTRACTS FROM THE ENDEMIC ARGANIA SPINOSA (L.) SKEELS FROM ALGERIAN SAHARA Open
The BuOH fractions prepared from 80% MeOH extract of the leaves from the endemic Saharan tree Argania spinosa (L.) Skeels exhibited the most potent antioxidant capacity ( IC50 = 2.41 ± 0.38 mg/mL for DPPH and 7.95 ± 0.54 mg/mL for superoxi…
View article: Green synthesis of silver nanoparticles from <i>Moringa oleifera</i> leaf extracts and its antimicrobial potential
Green synthesis of silver nanoparticles from <i>Moringa oleifera</i> leaf extracts and its antimicrobial potential Open
In this study we report on the synthesis of silver nanoparticles (AgNPs) from the leaf extracts of Moringa oleifera using sunlight irradiation as primary source of energy, and its antimicrobial potential. Silver nanoparticle formation was …
View article: Diversity of<i>Mycobacterium tuberculosis</i>Complex from Cattle Lymph Nodes in Eastern Cape Province
Diversity of<i>Mycobacterium tuberculosis</i>Complex from Cattle Lymph Nodes in Eastern Cape Province Open
Tuberculosis (TB) remains a major health challenge in South Africa and the condition in humans has been well researched and documented. However, investigations on the circulating Mycobacterium tuberculosis complex (MTBC) strains from cattl…
View article: Properties of a Wine Yeast Antagonist, Saccharomyces cerevisiae T206. A Review
Properties of a Wine Yeast Antagonist, Saccharomyces cerevisiae T206. A Review Open
CITATION: Vadasz, A. S., et. al. 2002. Properties of a wine yeast antagonist, saccharomyces cerevisiae T206. a review. South African Journal of Enology & Viticulture, 23(2):39-47, doi:10.21548/23-2-2154.