Patrick Kellner
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View article: The Prognostic Role of Cortisol and Glucose Dynamics in Cardiogenic Shock-Insights from a Prospective Observational Cohort
The Prognostic Role of Cortisol and Glucose Dynamics in Cardiogenic Shock-Insights from a Prospective Observational Cohort Open
Cardiogenic shock (CS) following myocardial infarction remains highly fatal. The prognostic value of dynamic metabolic markers—particularly glucose and cortisol—remains incompletely understood. In this prospective cohort study, 41 patients…
View article: The Thyroid-Heart Axis- Hormone Dynamics and Outcomes in Cardiogenic Shock Following Myocardial Infarction Short Title: Thyroid-Heart Axis in Cardiogenic Shock
The Thyroid-Heart Axis- Hormone Dynamics and Outcomes in Cardiogenic Shock Following Myocardial Infarction Short Title: Thyroid-Heart Axis in Cardiogenic Shock Open
Background Thyroid hormone alterations are common in critical illness and may reflect disease severity. However, their prognostic relevance in infarct-related cardiogenic shock remains insufficiently defined. Methods In this prospective co…
View article: The Prognostic Role of Cortisol and Glucose Dynamics in Cardiogenic Shock-Insights from a prospective observational cohort
The Prognostic Role of Cortisol and Glucose Dynamics in Cardiogenic Shock-Insights from a prospective observational cohort Open
Background Cardiogenic shock (CS) after myocardial infarction remains associated with excessive mortality. The prognostic relevance of early metabolic markers—specifically glucose and cortisol levels—remains insufficiently defined in this …
View article: The influence of different application patterns of propofol on the sedation courses during drug‐induced sleep endoscopy
The influence of different application patterns of propofol on the sedation courses during drug‐induced sleep endoscopy Open
Objective The course of sedation during drug‐induced sleep endoscopy (DISE) depends on the application pattern of the sedative drug. The depth of sedation should imitate light and deep sleep as well. Moreover, there should be as many breat…
View article: Accuracy of non-invasive sensors measuring core body temperature in cardiac surgery ICU patients – results from a monocentric prospective observational study
Accuracy of non-invasive sensors measuring core body temperature in cardiac surgery ICU patients – results from a monocentric prospective observational study Open
Purpose Temperature monitoring in the perioperative setting often represents a compromise between accuracy, invasiveness of probe placement, and patient comfort. Transcutaneous sensors using the Zero-Heat-Flux (ZHF) and Double-Sensor (DS) …
View article: Outcome of Emergency Pulmonary Lobectomy under ECMO Support in Patients with COVID-19
Outcome of Emergency Pulmonary Lobectomy under ECMO Support in Patients with COVID-19 Open
Background Not much is known about the results of nonelective anatomical lung resections in coronavirus disease 2019 (COVID-19) patients put on extracorporeal membrane oxygenation (ECMO). The aim of this study was to analyze the outcome of…
View article: ICU- and ventilator-free days with isoflurane or propofol as a primary sedative – A post- hoc analysis of a randomized controlled trial
ICU- and ventilator-free days with isoflurane or propofol as a primary sedative – A post- hoc analysis of a randomized controlled trial Open
Isoflurane via the ACD was not associated with more VFD but with more ICU-FD and less concomitant sedative use.
View article: A model of porcine polymicrobial septic shock
A model of porcine polymicrobial septic shock Open
Background Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. Mortality of patients with sepsis is high and largely unchanged throughout the past decades. Animal models have been widely used…
View article: Prolonged sedation with sevoflurane in comparison to intravenous sedation in critically ill patients – A randomized controlled trial
Prolonged sedation with sevoflurane in comparison to intravenous sedation in critically ill patients – A randomized controlled trial Open
ICU patients sedated with sevoflurane >48 h may return to spontaneous breathing faster, while the quality of sedation is comparable to a propofol-based sedation regime. Sevoflurane might be considered to be safe for long-term sedation in t…
View article: Aspiration of a Blister Pack Tablet with Tracheal Obstruction and Perforation: Emergency Tracheal Repair with Extracorporeal Membrane Oxygenation Support
Aspiration of a Blister Pack Tablet with Tracheal Obstruction and Perforation: Emergency Tracheal Repair with Extracorporeal Membrane Oxygenation Support Open
Background Airway management in case of acute tracheal injury is a challenging situation where the use of Extracorporeal Membrane Oxygenation (ECMO) has recently gained more importance. Case Description We report the case of a 60-year old …
View article: Methaemoglobinemia after Liposuction under Tumescent Local Anaesthesia – Diagnostic Value of Pulse Oximetry
Methaemoglobinemia after Liposuction under Tumescent Local Anaesthesia – Diagnostic Value of Pulse Oximetry Open
BACKGROUND: Tumescent local anaesthesia with prilocain can lead to clinically significant methemoglobin levels. New generation multiple wavelength pulse oximeters (e. g. Masimo Radical 7®) can measure methemoglobin levels. METHODS: In this…
View article: Sevoflurane Abolishes Oxygenation Impairment in a Long-Term Rat Model of Acute Lung Injury
Sevoflurane Abolishes Oxygenation Impairment in a Long-Term Rat Model of Acute Lung Injury Open
BACKGROUND: Patients experiencing acute lung injury (ALI) often need mechanical ventilation for which sedation may be required. In such patients, usually the first choice an intravenously administered drug. However, growing evidence sugges…