Patrick Maffe
YOU?
Author Swipe
View article: Pathogenic bacteria characterization through portable optical scatter device and machine learning
Pathogenic bacteria characterization through portable optical scatter device and machine learning Open
Our preliminary results from controlled experiments show that our portable device successfully quantified various pathogenic bacteria with reasonable accuracy through machine learning algorithms.
View article: <i>N</i>-Acetyl Cysteine-Decorated Nitric Oxide-Releasing Interface for Biomedical Applications
<i>N</i>-Acetyl Cysteine-Decorated Nitric Oxide-Releasing Interface for Biomedical Applications Open
Biomedical devices are vulnerable to infections and biofilm formation, leading to extended hospital stays, high expenditure, and increased mortality. Infections are clinically treated via the administration of systemic antibiotics, leading…
View article: Preventing <i>Staphylococci</i> Surgical Site Infections with a Nitric Oxide-Releasing Poly(lactic acid-<i>co</i>-glycolic acid) Suture Material
Preventing <i>Staphylococci</i> Surgical Site Infections with a Nitric Oxide-Releasing Poly(lactic acid-<i>co</i>-glycolic acid) Suture Material Open
Of the 27 million surgeries performed in the United States each year, a reported 2.6% result in a surgical site infection (SSI), and Staphylococci species are commonly the culprit. Alternative therapies, such as nitric oxide (NO)-releasing…
View article: <scp><i>S</i>‐Nitroso‐<i>N</i></scp>‐acetylpenicillamine impregnated latex: A new class of barrier contraception for the prevention of intercourse‐associated <scp>UTIs</scp>
<span><i>S</i>‐Nitroso‐<i>N</i></span>‐acetylpenicillamine impregnated latex: A new class of barrier contraception for the prevention of intercourse‐associated <span>UTIs</span> Open
Urinary tract infections (UTIs) are some of the most common infections seen in humans, affecting over half of the female population. Though easily and quickly treatable, if gone untreated for too long, UTIs can lead to narrowing of the ure…
View article: Catalytic effect of transition metal-doped medical grade polymer on <i>S</i>-nitrosothiol decomposition and its biological response
Catalytic effect of transition metal-doped medical grade polymer on <i>S</i>-nitrosothiol decomposition and its biological response Open
Comparative study investigates nitric oxide (NO)-releasing polymer composites with metal nanoparticles, revealing differential flux and biological effects, emphasizing the importance of a layered design for optimal NO release and biocompat…
View article: A dual‐action nitric oxide‐releasing slippery surface for extracorporeal organ support: Dynamic in vitro hemocompatibility evaluation
A dual‐action nitric oxide‐releasing slippery surface for extracorporeal organ support: Dynamic in vitro hemocompatibility evaluation Open
Numerous biomaterials have been developed for application in blood‐contacting medical devices to prevent thrombosis; however, few materials have been applied to full‐scale devices and evaluated for hemocompatibility under clinical blood fl…
View article: Surface-Catalyzed Nitric Oxide Release via a Metal Organic Framework Enhances Antibacterial Surface Effects
Surface-Catalyzed Nitric Oxide Release via a Metal Organic Framework Enhances Antibacterial Surface Effects Open
It has been previously demonstrated that metal nanoparticles embedded into polymeric materials doped with nitric oxide (NO) donor compounds can accelerate the release rate of NO for therapeutic applications. Despite the advantages of eleva…