Philipp Schüetz
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View article: Hospital resource use and in-hospital mortality before and during the COVID-19 pandemic: a nationwide cohort study
Hospital resource use and in-hospital mortality before and during the COVID-19 pandemic: a nationwide cohort study Open
INTRODUCTION: The COVID-19 pandemic has placed an enormous strain on the Swiss healthcare system. This study aims to assess the associations of the pandemic on Switzerland’s hospital resource use and in-hospital mortality among both COVID-…
View article: Good Outcome Following Attempted Resuscitation Score and Clinical Frailty Scale for Estimating Long-Term Mortality
Good Outcome Following Attempted Resuscitation Score and Clinical Frailty Scale for Estimating Long-Term Mortality Open
Importance In an aging and increasingly complex patient population, risk estimation tools are critical for optimizing clinical decision-making. The Clinical Frailty Scale (CFS) evaluates frailty and mortality risk, whereas the Good Outcome…
View article: Checklist-Guided Code Status Discussions in Patients for Whom Cardiopulmonary Resuscitation Is Considered Futile
Checklist-Guided Code Status Discussions in Patients for Whom Cardiopulmonary Resuscitation Is Considered Futile Open
Importance Code status discussions represent a fundamental aspect of advanced care planning and impose major challenges for clinicians in patients for whom cardiopulmonary resuscitation (CPR) is considered futile. Objective To investigate …
View article: Trimethylamine N-oxide (TMAO) as a prognostic marker among patients at nutritional risk
Trimethylamine N-oxide (TMAO) as a prognostic marker among patients at nutritional risk Open
BackgroundTrimethylamine N-oxide (TMAO), a metabolite produced by the gut microbiota, is highly influenced by dietary factors and is linked to negative health outcomes including all-cause mortality and cardiovascular events. We evaluated t…
View article: Hounsfield Unit Ranges as Inductive Bias for Intra-Clinical Learning of Data-Efficient CT Segmentation Models
Hounsfield Unit Ranges as Inductive Bias for Intra-Clinical Learning of Data-Efficient CT Segmentation Models Open
Automated tissue segmentation in medical imaging plays a critical role in clinical AI-assisted decision-making, and particularly in the assessment of body composition from CT scans. However, acquiring data and annotations of sufficient qua…
View article: Major Adverse Cardiac Events After Gastric Bypass vs Sleeve Gastrectomy
Major Adverse Cardiac Events After Gastric Bypass vs Sleeve Gastrectomy Open
Importance Metabolic bariatric surgery is the most effective and durable treatment for weight loss and improvement of cardiovascular diseases. With sleeve gastrectomy now surpassing gastric bypass as the most common procedure worldwide, co…
View article: Comparison of the inflammatory biomarkers IL- 6, TNF-α, and CRP to predict the effect of nutritional therapy on mortality in medical patients at risk of malnutrition
Comparison of the inflammatory biomarkers IL- 6, TNF-α, and CRP to predict the effect of nutritional therapy on mortality in medical patients at risk of malnutrition Open
Background Inflammation is a key driver of disease-related malnutrition and patients with high inflammation may not show the same benefits from nutritional therapy as other patients. We compared in an exploratory manner the prognostic abil…
View article: Mid‐regional pro‐adrenomedullin: A rapid sepsis biomarker for diagnosing spontaneous bacterial peritonitis in cirrhosis
Mid‐regional pro‐adrenomedullin: A rapid sepsis biomarker for diagnosing spontaneous bacterial peritonitis in cirrhosis Open
Background Spontaneous bacterial peritonitis (SBP) is a frequent and life‐threatening complication of cirrhosis, contributing to considerable morbidity and mortality. Methods A cross‐sectional derivation study was conducted to assess the d…
View article: Implementation of evidence-based clinical nutrition: Usability of the new digital platform clinicalnutrition.science
Implementation of evidence-based clinical nutrition: Usability of the new digital platform clinicalnutrition.science Open
AIM OF THE STUDY: Malnutrition is a common and complex challenge in inpatient and outpatient settings, associated with increased risk of morbidity and mortality. Its management is often neglected, despite strong evidence of the benefits of…
View article: Enhancing interprofessional ward rounds by identifying factors associated with low satisfaction and efficiency: a quantitative and qualitative national survey of Swiss healthcare professionals
Enhancing interprofessional ward rounds by identifying factors associated with low satisfaction and efficiency: a quantitative and qualitative national survey of Swiss healthcare professionals Open
AIMS OF THE STUDY: Interprofessional ward rounds are a cornerstone of patient-centred care for medical inpatients and offer opportunities to discuss and coordinate patient treatment and further management. We aimed to identify factors asso…
View article: Hospitalization Trends for Airway Infections and In-Hospital Complications in Cleft Lip and Palate
Hospitalization Trends for Airway Infections and In-Hospital Complications in Cleft Lip and Palate Open
Importance Cleft lip or palate is a prevalent birth defect, occurring in approximately 1 to 2 per 1000 newborns and often necessitating numerous hospitalizations. Specific rates of hospitalization and complication are underexplored. Object…
View article: Impact of nutrition interventions for malnourished patients: Introduction to health economics and outcomes research with findings from nutrition care studies
Impact of nutrition interventions for malnourished patients: Introduction to health economics and outcomes research with findings from nutrition care studies Open
Healthcare systems and patients today are challenged by high and ever‐escalating costs for care. With increasing costs and declining affordability, public and private healthcare payers are all seeking value in care. As the evidence regardi…
View article: The Association of the Essential Amino Acids Lysine, Methionine, and Threonine with Clinical Outcomes in Patients at Nutritional Risk: Secondary Analysis of a Randomized Clinical Trial
The Association of the Essential Amino Acids Lysine, Methionine, and Threonine with Clinical Outcomes in Patients at Nutritional Risk: Secondary Analysis of a Randomized Clinical Trial Open
Lysine, methionine, and threonine are essential amino acids with vital functions for muscle and connective tissue health, metabolic balance, and the immune system. During illness, the demand for these amino acids typically increases, which…
View article: Muscle matters: Prognostic implications of malnutrition and muscle health parameters in patients with cancer. A secondary analysis of a randomised trial
Muscle matters: Prognostic implications of malnutrition and muscle health parameters in patients with cancer. A secondary analysis of a randomised trial Open
ClinicalTrials.gov, number NCT02517476.
View article: Evaluation of health care utilisation and mortality in medical hospitalisations with multimorbidity and kidney disease, according to frailty: a nationwide cohort study
Evaluation of health care utilisation and mortality in medical hospitalisations with multimorbidity and kidney disease, according to frailty: a nationwide cohort study Open
INTRODUCTION: The impact of impaired kidney function on healthcare use among medical hospitalisations with multimorbidity and frailty is incompletely understood. In this study, we assessed the prevalence of acute kidney injury (AKI) and ch…
View article: The association of vaccination status with perceived discrimination in patients with COVID-19: results from a cross-sectional study
The association of vaccination status with perceived discrimination in patients with COVID-19: results from a cross-sectional study Open
STUDY AIMS: During the COVID-19 pandemic, there was increasing pressure to be vaccinated to prevent further spread of the virus and improve outcomes. At the same time, part of the population expressed reluctance to vaccination, for various…
View article: Association of tryptophan pathway metabolites with mortality and effectiveness of nutritional support among patients at nutritional risk: secondary analysis of a randomized clinical trial
Association of tryptophan pathway metabolites with mortality and effectiveness of nutritional support among patients at nutritional risk: secondary analysis of a randomized clinical trial Open
Tryptophan is an essential amino acid and is the precursor of many important metabolites and neurotransmitters. In malnutrition, the availability of tryptophan is reduced, potentially putting patients at increased risks. Herein, we investi…
View article: Rate of cardiovascular events up to 8 years after uncomplicated myocarditis: a nationwide cohort study
Rate of cardiovascular events up to 8 years after uncomplicated myocarditis: a nationwide cohort study Open
Aims While prognosis of acute myocarditis with uncomplicated presentation is perceived as benign, data on long-term outcomes are scarce. We evaluated rates of myocarditis-associated cardiovascular events after a first-time hospitalization …
View article: Association of Glutamine and Glutamate Metabolism with Mortality among Patients at Nutritional Risk—A Secondary Analysis of the Randomized Clinical Trial EFFORT
Association of Glutamine and Glutamate Metabolism with Mortality among Patients at Nutritional Risk—A Secondary Analysis of the Randomized Clinical Trial EFFORT Open
Glutamine and its metabolite glutamate serve as the main energy substrates for immune cells, and their plasma levels drop during severe illness. Therefore, glutamine supplementation in the critical care setting has been advocated. However,…
View article: Evaluation of Triple Whammy Prescriptions After the Implementation of a Drug Safety Algorithm
Evaluation of Triple Whammy Prescriptions After the Implementation of a Drug Safety Algorithm Open
The TW algorithm is highly sensitive and specific in identifying patients with TW therapy at risk for AKI. The algorithm may help to prevent AKI in TW patients in the future.
View article: Nutritional Support
Nutritional Support Open
Patients undergoing HCT, particularly allo-HCT, are at risk for malnutrition (Fuji et al., Food Nutr Sci 3:417–421, 2012). Based on “Supportive Care” in EBMT Handbook, 2009, by Tamás Masszi and Arno Mank.
View article: Inflammation and response to nutrition interventions
Inflammation and response to nutrition interventions Open
The complex interplay between nutrition and inflammation has become a major focus of research in recent years across different clinical settings and patient populations. Inflammation has been identified as a key driver for disease‐related …
View article: Global mortality and readmission rates following COPD exacerbation-related hospitalisation: a meta-analysis of 65 945 individual patients
Global mortality and readmission rates following COPD exacerbation-related hospitalisation: a meta-analysis of 65 945 individual patients Open
Background Exacerbations of COPD (ECOPD) have a major impact on patients and healthcare systems across the world. Precise estimates of the global burden of ECOPD on mortality and hospital readmission are needed to inform policy makers and …