Patrick R. Bader
YOU?
Author Swipe
View article: Effect of Acetazolamide on Pulmonary Hemodynamics and Right Heart Function in Healthy Adults Going to Altitude: A Randomized Controlled Trial
Effect of Acetazolamide on Pulmonary Hemodynamics and Right Heart Function in Healthy Adults Going to Altitude: A Randomized Controlled Trial Open
Background Exposure to high altitude triggers hypoxic pulmonary vasoconstriction with a rise in pulmonary artery pressure (PAP). This may lead to symptomatic pulmonary hypertension with impaired right heart function and exercise capacity. …
View article: Oxygen saturation and acute mountain sickness during repeated altitude exposures simulating high-altitude working schedules
Oxygen saturation and acute mountain sickness during repeated altitude exposures simulating high-altitude working schedules Open
This study aimed to quantify the effect of two consecutive prolonged, intermittent exposures to high and very high altitudes on oxygen saturation (SpO2) and acute mountain sickness (AMS). For this, healthy lowlanders (N = 21), a…
View article: A rare case of hyponatremia caused by urinary retention
A rare case of hyponatremia caused by urinary retention Open
An elderly man was hospitalized after a fall following an episode of dizziness. During the initial examination, he was found to have a distended bladder, caused by urinary retention. Moreover, he was diagnosed with severe hypoosmotic hypon…
View article: Corrigendum: Echocardiography and extravascular lung water during 3 weeks of exposure to high altitude in otherwise healthy asthmatics
Corrigendum: Echocardiography and extravascular lung water during 3 weeks of exposure to high altitude in otherwise healthy asthmatics Open
[This corrects the article DOI: 10.3389/fphys.2023.1214887.].
View article: Echocardiography and extravascular lung water during 3 weeks of exposure to high altitude in otherwise healthy asthmatics
Echocardiography and extravascular lung water during 3 weeks of exposure to high altitude in otherwise healthy asthmatics Open
Background: Asthma rehabilitation at high altitude is common. Little is known about the acute and subacute cardiopulmonary acclimatization to high altitude in middle-aged asthmatics without other comorbidities. Methods: In this prospective…
View article: Hypoxia-altitude simulation test to predict altitude-related adverse health effects in COPD patients
Hypoxia-altitude simulation test to predict altitude-related adverse health effects in COPD patients Open
Background/aims Amongst numerous travellers to high altitude (HA) are many with the highly prevalent COPD, who are at particular risk for altitude-related adverse health effects (ARAHE). We then investigated the hypoxia-altitude simulation…
View article: Acute high altitude exposure, acclimatization and re-exposure on nocturnal breathing
Acute high altitude exposure, acclimatization and re-exposure on nocturnal breathing Open
Background: Effects of prolonged and repeated high-altitude exposure on oxygenation and control of breathing remain uncertain. We hypothesized that prolonged and repeated high-altitude exposure will improve altitude-induced deoxygenation a…
View article: Severe Toxic Epidermal Necrolysis and Drug Reaction with Eosinophilia and Systemic Symptoms Overlap Syndrome Treated with Benralizumab: A Case Report
Severe Toxic Epidermal Necrolysis and Drug Reaction with Eosinophilia and Systemic Symptoms Overlap Syndrome Treated with Benralizumab: A Case Report Open
TEN/DRESS overlap syndrome can be difficult to diagnose, especially if it is masked by comorbidities in critically ill patients in intensive care units. The existing therapy for the two conditions is also a major challenge for the treating…
View article: A prospective cohort study about the effect of repeated living high and working higher on cerebral autoregulation in unacclimatized lowlanders
A prospective cohort study about the effect of repeated living high and working higher on cerebral autoregulation in unacclimatized lowlanders Open
View article: Efficient treatment of esophageal nutrition bezoars: dissolution outmatches removal—the Zurich approach
Efficient treatment of esophageal nutrition bezoars: dissolution outmatches removal—the Zurich approach Open
Enteral feed bezoars are difficult to treat and can lead to serious adverse events. There is no standardized treatment approach and various strategies have been suggested. We herein describe three cases of successful dissolutions of feed b…
View article: Exercise Performance in Central Asian Highlanders: A Cross-Sectional Study
Exercise Performance in Central Asian Highlanders: A Cross-Sectional Study Open
Forrer, Aglaia, Philipp M. Scheiwiller, Maamed Mademilov, Mona Lichtblau, Ulan Sheraliev, Nuriddin H. Marazhapov, Stéphanie Saxer, Patrick Bader, Paula Appenzeller, Shoira Aydaralieva, Aybermet Muratbekova, Talant M. Sooronbaev, Silvia Ulr…
View article: Acute Hemodynamic Effect of Acetazolamide in Patients With Pulmonary Hypertension Whilst Breathing Normoxic and Hypoxic Gas: A Randomized Cross-Over Trial
Acute Hemodynamic Effect of Acetazolamide in Patients With Pulmonary Hypertension Whilst Breathing Normoxic and Hypoxic Gas: A Randomized Cross-Over Trial Open
Aims: To test the acute hemodynamic effect of acetazolamide in patients with pulmonary hypertension (PH) under ambient air and hypoxia. Methods: Patients with pulmonary arterial or chronic thromboembolic PH (PAH/CTEPH) undergoing right hea…
View article: Effect of Fast Ascent, Acclimatization and Re-Exposure To 5050 m On Cerebral Autoregulation in Unacclimatized Lowlanders. A Prospective Cohort Study.
Effect of Fast Ascent, Acclimatization and Re-Exposure To 5050 m On Cerebral Autoregulation in Unacclimatized Lowlanders. A Prospective Cohort Study. Open
ABSTRACT Cerebral autoregulation (CA) is impaired during acute high-altitude (HA) exposure and effects of acclimatization and re-exposure on CA are unknown. In 18 healthy lowlanders (11 women), we hypothesized that the cerebral autoregulat…
View article: Closed-Loop Versus Conventional Mechanical Ventilation in COVID-19 ARDS
Closed-Loop Versus Conventional Mechanical Ventilation in COVID-19 ARDS Open
Background: Lung-protective ventilation is key in bridging patients suffering from COVID-19 acute respiratory distress syndrome (ARDS) to recovery. However, resource and personnel limitations during pandemics complicate the implementation …
View article: Extravascular lung water and cardiac function assessed by echocardiography in healthy lowlanders during repeated very high-altitude exposure
Extravascular lung water and cardiac function assessed by echocardiography in healthy lowlanders during repeated very high-altitude exposure Open
Exposure to 5050 m induced a rapid increase in sPAP. B-lines rose during prolonged exposures to 5050 m, despite gradual decrease in sPAP, indicating excessive hydrostatic pressure might not be solely responsible for EVLW-development. Repea…
View article: Pulmonary haemodynamic response to exercise in highlanders<i>versus</i>lowlanders
Pulmonary haemodynamic response to exercise in highlanders<i>versus</i>lowlanders Open
The aim of the study was to investigate the pulmonary haemodynamic response to exercise in Central Asian high- and lowlanders. This was a cross-sectional study in Central Asian highlanders (living >2500 m) compared with lowlanders (living …
View article: Right Atrial Pressure During Exercise Predicts Survival in Patients With Pulmonary Hypertension
Right Atrial Pressure During Exercise Predicts Survival in Patients With Pulmonary Hypertension Open
Background We investigated changes in right atrial pressure (RAP) during exercise and their prognostic significance in patients assessed for pulmonary hypertension (PH). Methods and Results Consecutive right heart catheterization data, inc…
View article: Asthma rehabilitation at high vs. low altitude and its impact on exhaled nitric oxide and sensitization patterns: Randomized parallel-group trial
Asthma rehabilitation at high vs. low altitude and its impact on exhaled nitric oxide and sensitization patterns: Randomized parallel-group trial Open
View article: Asthma rehabilitation at high vs. low altitude: randomized parallel-group trial
Asthma rehabilitation at high vs. low altitude: randomized parallel-group trial Open
Clinicaltrials.gov: NCT02741583, Registered April 18, 2016.
View article: Effect of domiciliary oxygen therapy on exercise capacity and quality of life in patients with pulmonary arterial or chronic thromboembolic pulmonary hypertension: a randomised, placebo-controlled trial
Effect of domiciliary oxygen therapy on exercise capacity and quality of life in patients with pulmonary arterial or chronic thromboembolic pulmonary hypertension: a randomised, placebo-controlled trial Open
Study question We investigated whether domiciliary oxygen therapy (DOXT) increases exercise capacity and quality of life in patients with pulmonary arterial or distal chronic thromboembolic pulmonary hypertension (PAH/CTEPH) presenting wit…
View article: Effects on Cognitive Functioning of Acute, Subacute and Repeated Exposures to High Altitude
Effects on Cognitive Functioning of Acute, Subacute and Repeated Exposures to High Altitude Open
Objective: Neurocognitive functions are affected by high altitude, however the altitude effects of acclimatization and repeated exposures are unclear. We investigated the effects of acute, subacute and repeated exposure to 5,050 m o…
View article: Effect of Acute, Subacute, and Repeated Exposure to High Altitude (5050 m) on Psychomotor Vigilance
Effect of Acute, Subacute, and Repeated Exposure to High Altitude (5050 m) on Psychomotor Vigilance Open
Aim: High altitude (HA) hypoxia may affect cognitive performance and sleep quality. Further, vigilance is reduced following sleep deprivation. We investigated the effect on vigilance, actigraphic sleep indices, and their relationshi…
View article: Acute hemodynamic changes by breathing hypoxic and hyperoxic gas mixtures in pulmonary arterial and chronic thromboembolic pulmonary hypertension
Acute hemodynamic changes by breathing hypoxic and hyperoxic gas mixtures in pulmonary arterial and chronic thromboembolic pulmonary hypertension Open