Patrick Schober
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View article: Safety and feasibility of intraoperative high PEEP titrated to the lowest driving pressure during anesthesia for minimally invasive abdominal surgery – Interim analysis of GENERATOR
Safety and feasibility of intraoperative high PEEP titrated to the lowest driving pressure during anesthesia for minimally invasive abdominal surgery – Interim analysis of GENERATOR Open
This research was funded by ZonMW, grant number 10390012110091.
View article: Energy levels in manual defibrillation after prior AED shock
Energy levels in manual defibrillation after prior AED shock Open
Adherence to escalating energy protocol by EMS during transition from defibrillation with AED to manual defibrillator is limited. Our data did not provide evidence for a relationship between adherence and clinical outcomes.
View article: Association of intraoperative end-tidal CO2 levels with postoperative outcomes: a patient-level analysis of two randomised clinical trials
Association of intraoperative end-tidal CO2 levels with postoperative outcomes: a patient-level analysis of two randomised clinical trials Open
NCT05550181.
View article: Effects of s-ketamine and midazolam on respiratory variability: A randomized controlled pilot trial
Effects of s-ketamine and midazolam on respiratory variability: A randomized controlled pilot trial Open
S-ketamine and midazolam are frequently used to provide sedation while maintaining spontaneous respiration. However, the effects of these agents on respiratory variability, which reflects the adaptability of the respiratory system, have no…
View article: Exploratory Analysis of Respiratory Variability in Relation to Disease Impact, Affective Symptoms, and Pain Sensitivity in Fibromyalgia
Exploratory Analysis of Respiratory Variability in Relation to Disease Impact, Affective Symptoms, and Pain Sensitivity in Fibromyalgia Open
While no direct association was found between respiratory variability and overall fibromyalgia impact, respiratory variability was associated with depression and pain sensitivity, both of which influence quality of life. These findings sug…
View article: Airway management by ambulance nurses during out-of-hospital cardiac arrest
Airway management by ambulance nurses during out-of-hospital cardiac arrest Open
During cardiopulmonary resuscitation (CPR) by ambulance nurses, the use of SADs increased, and that of ETTs decreased. Although ETT first pass success improved, it was lower than the guideline-recommended standard for performing intubation…
View article: Automated cardiac arrest detection and emergency service alerting using device-independent smartwatch technology: proof-of-principle
Automated cardiac arrest detection and emergency service alerting using device-independent smartwatch technology: proof-of-principle Open
This study demonstrates the feasibility of detecting circulatory arrest using commercially available smartwatch sensors, achieving high sensitivity and specificity. Additionally, we integrated an automated alerting system with emergency ne…
View article: Classification of trauma-related preventable death; a Delphi procedure in The Netherlands
Classification of trauma-related preventable death; a Delphi procedure in The Netherlands Open
The identification of trauma-related preventable death is essential in the evaluation of trauma care. This study elucidates the difficulty of multidisciplinary consensus. However, a propensity towards consensus on a clinical definition, an…
View article: Different effects of epidural versus paravertebral analgesia on respiratory rate variability after oesophagectomy
Different effects of epidural versus paravertebral analgesia on respiratory rate variability after oesophagectomy Open
View article: Predicting admission to and length of stay in intensive care units after general anesthesia: Time-dependent role of pre- and intraoperative data for clinical decision-making
Predicting admission to and length of stay in intensive care units after general anesthesia: Time-dependent role of pre- and intraoperative data for clinical decision-making Open
Intraoperative data are crucial for immediate postoperative decisions, while preoperative data are essential for extended LOS predictions. These findings highlight the need for a comprehensive risk assessment approach in perioperative care…
View article: Energy Levels in Manual Defibrillation after Prior Aed Shock
Energy Levels in Manual Defibrillation after Prior Aed Shock Open
View article: Associations of intraoperative end–tidal CO2 levels with postoperative outcome–secondary analysis of a worldwide observational study
Associations of intraoperative end–tidal CO2 levels with postoperative outcome–secondary analysis of a worldwide observational study Open
LAS VEGAS was registered at Clinicaltrials.gov (NCT01601223), first posted on May 17, 2012.
View article: Understanding the Acid-Base Response to Respiratory Derangements: Finding, and Clinically Applying, the In Vivo Base Excess
Understanding the Acid-Base Response to Respiratory Derangements: Finding, and Clinically Applying, the In Vivo Base Excess Open
OBJECTIVES: To evaluate the base excess response during acute in vivo carbon dioxide changes. DESIGN: Secondary analysis of individual participant data from experimental studies. SETTING: Three experimental studies investigating the effect…
View article: Adapting to Adulthood: A Review of Transition Strategies for Osteogenesis Imperfecta
Adapting to Adulthood: A Review of Transition Strategies for Osteogenesis Imperfecta Open
Osteogenesis Imperfecta (OI), known as “brittle bone disease,” presents a rare genetic disorder characterized by bone fragility, often accompanied by skeletal deformities and extraskeletal complications. OI is primarily associated with col…
View article: Editorial for Recent Developments in Emergency Trauma Management
Editorial for Recent Developments in Emergency Trauma Management Open
This Special Issue addresses several specific aspects of emergency trauma management in considerable depth (contributions I–VI) [...]
View article: Simulating the methodological bias in the ATLS classification of hypovolemic shock: a critical reappraisal of the base deficit renaissance
Simulating the methodological bias in the ATLS classification of hypovolemic shock: a critical reappraisal of the base deficit renaissance Open
View article: Establishing Outcome Parameters for Helicopter Emergency Medical Services Research in The Netherlands: Results of a Mixed-Methods Delphi Consensus Study
Establishing Outcome Parameters for Helicopter Emergency Medical Services Research in The Netherlands: Results of a Mixed-Methods Delphi Consensus Study Open
In conclusion, this study identified 25 outcome parameters relevant for Dutch physician staffed HEMS care. These parameters should be considered when designing future studies and should be routinely collected for each dispatch if possible.
View article: Association between caseload volume and outcomes in left ventricular assist device implantations – a <scp>EUROMACS</scp> analysis
Association between caseload volume and outcomes in left ventricular assist device implantations – a <span>EUROMACS</span> analysis Open
Aims This EUROMACS study was conducted with the primary aim of investigating the association between a centre's annual caseload and postoperative outcomes among patients undergoing left ventricular assist device (LVAD) implantation. Method…
View article: Ventilation during cardiopulmonary resuscitation: A narrative review
Ventilation during cardiopulmonary resuscitation: A narrative review Open
Ventilation during cardiopulmonary resuscitation is vital to achieve optimal oxygenation but continues to be a subject of ongoing debate. This narrative review aims to provide an overview of various components and challenges of ventilation…
View article: Investigating Users’ Attitudes Toward Automated Smartwatch Cardiac Arrest Detection: Cross-Sectional Survey Study
Investigating Users’ Attitudes Toward Automated Smartwatch Cardiac Arrest Detection: Cross-Sectional Survey Study Open
Background Out-of-hospital cardiac arrest (OHCA) is a leading cause of mortality in the developed world. Timely detection of cardiac arrest and prompt activation of emergency medical services (EMS) are essential, yet challenging. Automated…
View article: Long-Term Socioeconomic and Mental Health Changes After Out-of-Hospital Cardiac Arrest in Women and Men
Long-Term Socioeconomic and Mental Health Changes After Out-of-Hospital Cardiac Arrest in Women and Men Open
BACKGROUND: Long-term effects of out-of-hospital cardiac arrest (OHCA) may affect the ability to work and mental health. Our aim was to analyze 5-year changes in socioeconomic and mental health outcomes after OHCA in women and men. METHODS…
View article: Appropriate Timing of End-of-Life Care: A Dutch Policy Analysis and Opportunities for Improvement
Appropriate Timing of End-of-Life Care: A Dutch Policy Analysis and Opportunities for Improvement Open
Background: The Exceptional Medical Expenses Act (EMEA) guaranteed public financing for the costs of end-of-life care in The Netherlands until 2015. A life expectancy shorter than three months was a prerequisite for a patient to qualify. O…
View article: Ventilation during cardiopulmonary resuscitation with mechanical chest compressions: How often are two insufflations being given during the 3-second ventilation pauses?
Ventilation during cardiopulmonary resuscitation with mechanical chest compressions: How often are two insufflations being given during the 3-second ventilation pauses? Open
Providing two insufflations during pauses in mechanical chest compressions is mostly unsuccessful. We recommend developing strategies to improve giving insufflations when using mechanical chest compression devices. Increasing the pause dur…
View article: Classification of trauma-related preventable death; protocol of a Delphi procedure
Classification of trauma-related preventable death; protocol of a Delphi procedure Open
Background Trauma-related (preventable) death is used to evaluate the management and quality of trauma care worldwide. Therefore, it is necessary to identify fatalities in the trauma care population and assess them on preventability. Howev…
View article: Effect of Daytime versus Nighttime on Prehospital Care and Outcomes after Severe Traumatic Brain Injury
Effect of Daytime versus Nighttime on Prehospital Care and Outcomes after Severe Traumatic Brain Injury Open
Background/Objectives: Severe traumatic brain injury (TBI) is a frequent cause of morbidity and mortality worldwide. In the Netherlands, suspected TBI is a criterion for the dispatch of the physician-staffed helicopter emergency medical se…
View article: Prehospital Care of Severely Intoxicated Patients by a Dutch Physician-Staffed Helicopter Emergency Medical Services: A Retrospective Study
Prehospital Care of Severely Intoxicated Patients by a Dutch Physician-Staffed Helicopter Emergency Medical Services: A Retrospective Study Open
In this study, we found that P-HEMS crews might complement usual prehospital care by ambulance crews for patients with severe intoxications by bringing advanced skills (eg, airway management and specific antidotes) to the scene.
View article: Etomidate versus Ketamine as Prehospital Induction Agent in Patients with Suspected Severe Traumatic Brain Injury
Etomidate versus Ketamine as Prehospital Induction Agent in Patients with Suspected Severe Traumatic Brain Injury Open
Background Severe traumatic brain injury is a leading cause of morbidity and mortality among young people around the world. Prehospital care focuses on the prevention and treatment of secondary brain injury and commonly includes tracheal i…
View article: Traumatic Cardiac Arrest—A Narrative Review
Traumatic Cardiac Arrest—A Narrative Review Open
A paradigm shift in traumatic cardiac arrest (TCA) perception switched the traditional belief of futility of TCA resuscitation to a more optimistic perspective, at least in selected cases. The goal of TCA resuscitation is to rapidly and ag…
View article: Does preoperative multidisciplinary team assessment of high-risk patients improve the safety and outcomes of patients undergoing surgery?
Does preoperative multidisciplinary team assessment of high-risk patients improve the safety and outcomes of patients undergoing surgery? Open
View article: Ventilation During Cardiopulmonary Resuscitation with Mechanical Chest Compressions: How Often are Two Insufflations Being Given During the 3-Second Ventilation Pauses?
Ventilation During Cardiopulmonary Resuscitation with Mechanical Chest Compressions: How Often are Two Insufflations Being Given During the 3-Second Ventilation Pauses? Open