Patrick Sheahan
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View article: Lymph Nodal Yield and Prediction of Mortality in Oral Squamous Cell Carcinoma Patients
Lymph Nodal Yield and Prediction of Mortality in Oral Squamous Cell Carcinoma Patients Open
Objective Lymph nodal yield (LNY) is increasingly used in oral squamous cell carcinoma (OSCC) research as a prognostic factor and quality metric but remain to be validated across independent OSCC cohorts. Study design Retrospective cohort …
View article: Impact of <scp>WPOI‐5</scp> on Risk of Regional Recurrence in Early Oral Cancer With <scp>pN0</scp> Neck
Impact of <span>WPOI‐5</span> on Risk of Regional Recurrence in Early Oral Cancer With <span>pN0</span> Neck Open
Introduction Regional recurrence (RR) has been reported to occur in 7%–17% of patients with oral squamous cell carcinoma (OSCC) and pathologically negative (pN0) necks. Risk factors for isolated RR, in the absence of simultaneous local rec…
View article: Significance of location and extent of perineural invasion in early‐stage oral cavity squamous cell carcinoma
Significance of location and extent of perineural invasion in early‐stage oral cavity squamous cell carcinoma Open
Aims Perineural invasion (PNI) is associated with survival in oral cavity squamous cell carcinoma (OCSCC). There is evidence to suggest that PNI location and extent may be of additional significance. The primary aim of this study was to ev…
View article: Correction: Mobile multi-configuration clinical translational Raman system for oral cancer application
Correction: Mobile multi-configuration clinical translational Raman system for oral cancer application Open
Correction for ‘Mobile multi-configuration clinical translational Raman system for oral cancer application’ by Siddra Maryam et al. , Analyst , 2023, 148 , 1514–1523, https://doi.org/10.1039/D2AN01921C.
View article: Impact of Close Margins on Oral Cancer Outcomes According to the Oral Subsite
Impact of Close Margins on Oral Cancer Outcomes According to the Oral Subsite Open
Background The prognostic significance of close margins in oral squamous cell carcinoma (OSCC) is controversial. We wished to investigate the impact of close margins on the risk of local recurrence (LR) in OSCC according to the oral subsit…
View article: Visceral Perforation Complicating BRAF/MEK Targeted Therapy of Papillary Thyroid Carcinoma with Anaplastic Areas
Visceral Perforation Complicating BRAF/MEK Targeted Therapy of Papillary Thyroid Carcinoma with Anaplastic Areas Open
Anaplastic thyroid cancer (ATC) is considered to be one of the most virulent, treatment-refractory malignancies. Recent molecular insights into the biology of thyroid cancer have transformed ATC management, and BRAF/MEK targeted therapy is…
View article: Visceral Perforation Complicating BRAF/MEK Targeted Therapy of Papillary Thyroid Carcinoma with Anaplastic Areas
Visceral Perforation Complicating BRAF/MEK Targeted Therapy of Papillary Thyroid Carcinoma with Anaplastic Areas Open
Anaplastic thyroid cancer (ATC) is considered to be one of the most virulent, treatment refractory, malignancies. Recent molecular insights into the biology of thyroid cancer have transformed ATC management and BRAF/MEK targeted therapy is…
View article: Airway decision making in major head and neck surgery: Irish multicenter, multidisciplinary recommendations
Airway decision making in major head and neck surgery: Irish multicenter, multidisciplinary recommendations Open
Major head and neck surgery poses a threat to perioperative airway patency. Adverse airway events are associated with significant morbidity, potentially leading to hypoxic brain injury and even death. Following a review of the literature, …
View article: AB128. SOH24AB_056. The non-recurrent laryngeal nerve in an Irish thyroid surgery population: an 11-year experience
AB128. SOH24AB_056. The non-recurrent laryngeal nerve in an Irish thyroid surgery population: an 11-year experience Open
Background: The non-recurrent laryngeal nerve (NRLN) is a rare anatomical variant of the recurrent laryngeal nerve (RLN). It occurs where abnormalities of the aortic arch are present, such as aberrant right subclavian artery, and may be as…
View article: Outcomes of Immediate Total Thyroidectomy in First-Side Loss of Neuromonitoring Signal
Outcomes of Immediate Total Thyroidectomy in First-Side Loss of Neuromonitoring Signal Open
Importance Use of intraoperative neuromonitoring (IONM) during thyroidectomy can nearly eliminate the risk of postoperative bilateral vocal cord palsy (VCP) by indicating staged surgery in cases of loss of signal (LOS) on the first side of…
View article: Pattern of regional recurrence after selective neck dissection for clinically positive neck in mucosal squamous carcinoma
Pattern of regional recurrence after selective neck dissection for clinically positive neck in mucosal squamous carcinoma Open
Background Selective neck dissection (SND) has traditionally been applied to clinically negative (cN0) necks in mucosal squamous cell carcinoma (SCC). We aimed to examine the oncological safety and patterns of regional recurrence (RR) of S…
View article: Significance of Worst Pattern of Invasion-5 in Early-Stage Oral Cavity Squamous Cell Carcinoma
Significance of Worst Pattern of Invasion-5 in Early-Stage Oral Cavity Squamous Cell Carcinoma Open
Background There is an ongoing need to identify pathologic prognosticators in early-stage oral cavity squamous cell carcinoma (OCSCC) to aid selection of patients who may benefit from adjuvant treatment. The objective of this study was to …
View article: Significance of Worst Pattern of Invasion 5 in Early-Stage Oral Cavity Squamous Cell Carcinoma
Significance of Worst Pattern of Invasion 5 in Early-Stage Oral Cavity Squamous Cell Carcinoma Open
Background There is an ongoing need to identify pathologic prognosticators in early-stage oral cavity squamous cell carcinoma (OCSCC) to aid selection of patients who may benefit from adjuvant treatment. The objective of this study was to …
View article: AB175. SOH23ABS_026. An unusual case of thyroglossal duct cyst carcinoma presenting in the sublingual space, and its multidisciplinary management
AB175. SOH23ABS_026. An unusual case of thyroglossal duct cyst carcinoma presenting in the sublingual space, and its multidisciplinary management Open
Background: Thyroglossal duct cysts (TGDCs) are the most common congenital anomaly of thyroid gland development, with a <1% risk of malignancy occurring within them. It's rare for a TGDC to be located in floor of the mouth region or the su…
View article: Mobile multi-configuration clinical translational Raman system for oral cancer application
Mobile multi-configuration clinical translational Raman system for oral cancer application Open
Early diagnosis of oral cancer is critical to improve the survival rate of patients.
View article: Label-Free Optical Spectroscopy for Early Detection of Oral Cancer
Label-Free Optical Spectroscopy for Early Detection of Oral Cancer Open
Oral cancer is the 16th most common cancer worldwide. It commonly arises from painless white or red plaques within the oral cavity. Clinical outcome is highly related to the stage when diagnosed. However, early diagnosis is complex owing t…
View article: Safety of emergency ENT procedures during COVID-19 pandemic
Safety of emergency ENT procedures during COVID-19 pandemic Open
Aims \nThe aim of this study is to assess the safety of performing various emergency ENT procedures in a single institution during the COVID-19 pandemic and the impacts on patients and healthcare workers that potentially would have risen f…
View article: Outcomes of Preoperative Testing for SARS-CoV-2 in Otolaryngology Surgery during the Pandemic
Outcomes of Preoperative Testing for SARS-CoV-2 in Otolaryngology Surgery during the Pandemic Open
Objective: Preoperative testing for COVID-19 has become widely established to avoid inadvertent surgery on patients with COVID-19 and prevent hospital outbreaks, however, there is limited evidence underpinning new protocols. We wished to s…
View article: Comparison of royal college of pathologists and college of american pathologists definition for positive margins in oral cavity squamous cell carcinoma
Comparison of royal college of pathologists and college of american pathologists definition for positive margins in oral cavity squamous cell carcinoma Open
Involved main specimen margin as defined by CAP guidance has the advantage of being an independent prognosticator of LR and survival in our cohort.
View article: Predictive value of postoperative day 1 parathyroid hormone levels for early and late hypocalcaemia after thyroidectomy
Predictive value of postoperative day 1 parathyroid hormone levels for early and late hypocalcaemia after thyroidectomy Open
Purpose Early parathyroid hormone (PTH) levels after total thyroidectomy can predict patients at low risk of hypocalcaemia who can be discharged early without calcium supplementation. For centres without facility to perform early PTH level…
View article: Vocal cord paralysis as a presenting sign of autosomal recessive spinocerebellar atrophy type 10
Vocal cord paralysis as a presenting sign of autosomal recessive spinocerebellar atrophy type 10 Open
Acquired vocal cord paralysis (VCP) is caused by dysfunction or injury of one or both recurrent laryngeal nerves. Here we report a 41-year-old man with spinocerebellar atrophy, autosomal recessive type 10 (SCAR10) due to an autosomal reces…
View article: Association between number of parathyroid glands identified during total thyroidectomy and functional parathyroid preservation
Association between number of parathyroid glands identified during total thyroidectomy and functional parathyroid preservation Open
Purpose Systematic identification of all 4 parathyroid glands has been recommended during total thyroidectomy (TT); however, it is unclear whether this strategy necessarily translates into optimized functional parathyroid preservation. We …
View article: Pre‐operative testing for <scp>SARS‐CoV</scp>‐2 and outcomes in otolaryngology surgery during the pandemic: A <scp>multi‐center</scp> experience
Pre‐operative testing for <span>SARS‐CoV</span>‐2 and outcomes in otolaryngology surgery during the pandemic: A <span>multi‐center</span> experience Open
Introduction Preoperative testing for COVID‐19 has become widely established to avoid inadvertent surgery on patients with COVID‐19 and prevent hospital outbreaks. Methods A prospective cross sectional study was carried out in two universi…
View article: Outcomes of preoperative real-time polymerase chain reaction testing for SARS CoV-2 in elective otolaryngology surgical patients during the pandemic: a prospective cohort study
Outcomes of preoperative real-time polymerase chain reaction testing for SARS CoV-2 in elective otolaryngology surgical patients during the pandemic: a prospective cohort study Open
Real-time polymerase chain reaction (RT-PCR) is used to rule out SARS-CoV-2 prior to surgery, however few studies have evaluated patients with negative testing after surgery. Some 499 patients with negative tests were followed for 14 days …
View article: Tissue sealant versus surgical drain following parotidectomy
Tissue sealant versus surgical drain following parotidectomy Open
Sialocele and salivary fistula are recognised complications of parotid surgery and have been reported to be more common with less extensive parotidectomy. We investigated the efficacy of tissue sealant(Cunniffe et al., 2019) 1 as an altern…
View article: Anaplastic thyroid cancer: outcomes of trimodal therapy
Anaplastic thyroid cancer: outcomes of trimodal therapy Open
Despite poor prognosis of ATC, selected patients with operable tumours may achieve high locoregional control rates with trimodal therapy, with possibility of long-term survival in select cases.
View article: Risk of disease transmission from flexible nasoendoscopy during the coronavirus disease 2019 pandemic
Risk of disease transmission from flexible nasoendoscopy during the coronavirus disease 2019 pandemic Open
Background Concerns have emerged regarding infection transmission during flexible nasoendoscopy. Methods Information was gathered prospectively on flexible nasoendoscopy procedures performed between March and June 2020. Patients and health…
View article: Use of intraoperative neural monitoring for prognostication of recovery of vocal mobility and reduction of permanent vocal paralysis after thyroidectomy
Use of intraoperative neural monitoring for prognostication of recovery of vocal mobility and reduction of permanent vocal paralysis after thyroidectomy Open
Introduction The benefits of intraoperative neural monitoring (IONM) of recurrent laryngeal nerve (RLN) on post‐thyroidectomy vocal cord palsy (VCP) rates are contentious. We wished to study impact of IONM on permanent VCP after thyroidect…