Patrick T. C. van den Bogaard
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View article: Increased d-alanylation of lipoteichoic acid and a thickened septum are main determinants in the nisin resistance mechanism of Lactococcus lactis
Increased d-alanylation of lipoteichoic acid and a thickened septum are main determinants in the nisin resistance mechanism of Lactococcus lactis Open
Nisin is a post-translationally modified antimicrobial peptide produced by Lactococcus lactis which binds to lipid II in the membrane to form pores and inhibit cell-wall synthesis. A nisin-resistant (Nis(R)) strain of L. lactis, which is a…
View article: Hierarchical control versus autoregulation of carbohydrate utilization in bacteria
Hierarchical control versus autoregulation of carbohydrate utilization in bacteria Open
The involvement of phosphoenolpyruvate:sugar phosphotransferase (PTS) proteins, like HPr and IIA Glc , in the regulation of carbohydrate utilization has been well established in Gram-negative and Gram-positive bacteria. The majority of the…
View article: Activation of Silent <i>gal</i> Genes in the <i>lac-gal</i> Regulon of <i>Streptococcus thermophilus</i>
Activation of Silent <i>gal</i> Genes in the <i>lac-gal</i> Regulon of <i>Streptococcus thermophilus</i> Open
Streptococcus thermophilus strain CNRZ 302 is unable to ferment galactose, neither that generated intracellularly by lactose hydrolysis nor the free sugar. Nevertheless, sequence analysis and complementation studies with Escherichia coli d…
View article: Control of Lactose Transport, β-Galactosidase Activity, and Glycolysis by CcpA in <i>Streptococcus thermophilus</i> : Evidence for Carbon Catabolite Repression by a Non-Phosphoenolpyruvate-Dependent Phosphotransferase System Sugar
Control of Lactose Transport, β-Galactosidase Activity, and Glycolysis by CcpA in <i>Streptococcus thermophilus</i> : Evidence for Carbon Catabolite Repression by a Non-Phosphoenolpyruvate-Dependent Phosphotransferase System Sugar Open
Streptococcus thermophilus , unlike many other gram-positive bacteria, prefers lactose over glucose as the primary carbon and energy source. Moreover, lactose is not taken up by a phosphoenolpyruvate-dependent phosphotransferase system (PT…