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View article: Deep Neural Networks for Analysis of Microscopy Images—Synthetic Data Generation and Adaptive Sampling
Deep Neural Networks for Analysis of Microscopy Images—Synthetic Data Generation and Adaptive Sampling Open
The analysis of microscopy images has always been an important yet time consuming process in materials science. Convolutional Neural Networks (CNNs) have been very successfully used for a number of tasks, such as image segmentation. Howeve…
View article: Deep Neural Networks for Analysis of Microscopy Images—Synthetic Data Generation and Adaptive Sampling
Deep Neural Networks for Analysis of Microscopy Images—Synthetic Data Generation and Adaptive Sampling Open
The analysis of microscopy images has always been an important yet time consuming process in materials science. Convolutional Neural Networks (CNNs) have been very successfully used for a number of tasks, such as image segmentation. Howeve…
View article: A GPU-based caching strategy for multi-material linear elastic FEM on regular grids
A GPU-based caching strategy for multi-material linear elastic FEM on regular grids Open
In this study, we present a novel strategy to the method of finite elements (FEM) of linear elastic problems of very high resolution on graphic processing units (GPU). The approach exploits regularities in the system matrix that occur in r…
View article: Correlative Fluorescence- and Electron Microscopy of Whole Breast Cancer Cells Reveals Different Distribution of ErbB2 Dependent on Underlying Actin
Correlative Fluorescence- and Electron Microscopy of Whole Breast Cancer Cells Reveals Different Distribution of ErbB2 Dependent on Underlying Actin Open
Epidermal growth factor receptor 2 (ErbB2) is found overexpressed in several cancers, such as gastric, and breast cancer, and is, therefore, an important therapeutic target. ErbB2 plays a central role in cancer cell invasiveness, and is as…
View article: Correlative Fluorescence- and Electron Microscopy of Whole Breast Cancer Cells Reveals Different Distribution of ErbB2 Dependent on Underlying Actin
Correlative Fluorescence- and Electron Microscopy of Whole Breast Cancer Cells Reveals Different Distribution of ErbB2 Dependent on Underlying Actin Open
Epidermal growth factor receptor 2 (ErbB2) is found overexpressed in several cancers, such as gastric, and breast cancer, and is, therefore, an important therapeutic target. ErbB2 plays a central role in cancer cell invasiveness, and is as…
View article: Deep Learning for Sparse Scanning Electron Microscopy
Deep Learning for Sparse Scanning Electron Microscopy Open
Journal Article Deep Learning for Sparse Scanning Electron Microscopy Get access Patrick Trampert, Patrick Trampert German Research Center for Artificial Intelligence GmbH (DFKI), Saarbrücken, GermanySaarland University, 66123 Saarbrücken,…
View article: 3D exemplar-based image inpainting in electron microscopy
3D exemplar-based image inpainting in electron microscopy Open
In electron microscopy (EM) a common problem is the non-availability of data, which causes artefacts in reconstructions. In this thesis the goal is to generate artificial data where missing in EM by using exemplar-based inpainting (EBI). W…
View article: Fact or Fiction: Maximal Image Quality with Minimal Dwell Time
Fact or Fiction: Maximal Image Quality with Minimal Dwell Time Open
An abstract is not available for this content so a preview has been provided. As you have access to this content, a full PDF is available via the ‘Save PDF’ action button.
View article: Exemplar-Based Inpainting Based on Dictionary Learning for Sparse Scanning Electron Microscopy
Exemplar-Based Inpainting Based on Dictionary Learning for Sparse Scanning Electron Microscopy Open
An abstract is not available for this content so a preview has been provided. As you have access to this content, a full PDF is available via the 'Save PDF' action button.
View article: Blob-based Algebraic Reconstruction Technique for Computed Laminography
Blob-based Algebraic Reconstruction Technique for Computed Laminography Open
An abstract is not available for this content so a preview has been provided. As you have access to this content, a full PDF is available via the ‘Save PDF’ action button.
View article: How should a fixed budget of dwell time be spent in scanning electron\n microscopy to optimize image quality?
How should a fixed budget of dwell time be spent in scanning electron\n microscopy to optimize image quality? Open
In scanning electron microscopy, the achievable image quality is often\nlimited by a maximum feasible acquisition time per dataset. Particularly with\nregard to three-dimensional or large field-of-view imaging, a compromise must\nbe found …
View article: Space-Filling Curve Indices as Acceleration Structure for Exemplar-Based Inpainting
Space-Filling Curve Indices as Acceleration Structure for Exemplar-Based Inpainting Open
Exemplar-based inpainting is the process of reconstructing missing parts of an image by searching the remaining data for patches that fit seamlessly. The image is completed to a plausible-looking solution by repeatedly inserting the patch …
View article: High-Throughput Large Volume SEM Workflow using Sparse Scanning and In-painting Algorithms Inspired by Compressive Sensing
High-Throughput Large Volume SEM Workflow using Sparse Scanning and In-painting Algorithms Inspired by Compressive Sensing Open
We are presenting a new extension to our Cell and Tissue/Neurobiology large volume imaging workflow, with the goal of increasing acquisition speed by more than five times.Instead of scanning dense square-grid frames, in the conventional wa…
View article: Spherically symmetric volume elements as basis functions for image reconstructions in computed laminography
Spherically symmetric volume elements as basis functions for image reconstructions in computed laminography Open
BACKGROUND: Laminography is a tomographic technique that allows three-dimensional imaging of flat, elongated objects that stretch beyond the extent of a reconstruction volume. Laminography datasets can be reconstructed using iterative algo…
View article: Dictionary-based Filling of the Missing Wedge in Electron Tomography
Dictionary-based Filling of the Missing Wedge in Electron Tomography Open
inpainting is capable of generating meaningful projections where data is missing due to limited tilt range in data acquisition leading to reduced missing wedge artifacts in subsequent reconstructions.[3]
View article: Combined Tilt- and Focal-Series Tomography for HAADF-STEM
Combined Tilt- and Focal-Series Tomography for HAADF-STEM Open
The primary means to study cellular ultrastructure in three dimensions (3D) with nanoscale resolution is currently tilt-series transmission electron microscopy (TEM) [1–2]. In this imaging modality, images are acquired at different project…
View article: Combining miRNA and mRNA Expression Profiles in Wilms Tumor Subtypes
Combining miRNA and mRNA Expression Profiles in Wilms Tumor Subtypes Open
Wilms tumor (WT) is the most common childhood renal cancer. Recent findings of mutations in microRNA (miRNA) processing proteins suggest a pivotal role of miRNAs in WT genesis. We performed miRNA expression profiling of 36 WTs of different…
View article: Multi-omics enrichment analysis using the GeneTrail2 web service
Multi-omics enrichment analysis using the GeneTrail2 web service Open
Motivation: Gene set analysis has revolutionized the interpretation of high-throughput transcriptomic data. Nowadays, with comprehensive studies that measure multiple -omics from the same sample, powerful tools for the integrative analysis…