Patrizia Simoni
YOU?
Author Swipe
View article: Metabolic Bile Acid Profile Impairments in Dogs Affected by Chronic Inflammatory Enteropathy
Metabolic Bile Acid Profile Impairments in Dogs Affected by Chronic Inflammatory Enteropathy Open
Bile acids (BAs), endogenous acidic steroids synthetized from cholesterol in the liver, play a key role in the gut–liver axis physiopathology, including in hepatotoxicity, intestinal inflammatory processes, and cholesterol homeostasis. Fae…
View article: 5-MTHF enhances the portal pressure reduction achieved with propranolol in patients with cirrhosis: A randomized placebo-controlled trial
5-MTHF enhances the portal pressure reduction achieved with propranolol in patients with cirrhosis: A randomized placebo-controlled trial Open
View article: Extraction method for the multiresidue analysis of legacy and emerging pollutants in marine mussels from the Adriatic Sea
Extraction method for the multiresidue analysis of legacy and emerging pollutants in marine mussels from the Adriatic Sea Open
View article: Treatment with PCSK9 Inhibitor Evolocumab Improves Vascular Oxidative Stress and Arterial Stiffness in Hypercholesterolemic Patients with High Cardiovascular Risk
Treatment with PCSK9 Inhibitor Evolocumab Improves Vascular Oxidative Stress and Arterial Stiffness in Hypercholesterolemic Patients with High Cardiovascular Risk Open
Atherosclerosis and atherosclerotic-related cardiovascular diseases (ASCVD) are characterized by high serum levels of low-density lipoprotein cholesterol (LDL-C) that can promote the generation of reactive oxygen species (ROS). To answer t…
View article: New Insights into Bile Acids Related Signaling Pathways in the Onset of Colorectal Cancer
New Insights into Bile Acids Related Signaling Pathways in the Onset of Colorectal Cancer Open
Colorectal cancer (CRC) ranks as the second among the causes of tumor death worldwide, with an estimation of 1.9 million new cases in 2020 and more than 900,000 deaths. This rate might increase by 60% over the next 10 years. These data are…
View article: Fermentation of Vaccinium floribundum Berries with Lactiplantibacillus plantarum Reduces Oxidative Stress in Endothelial Cells and Modulates Macrophages Function
Fermentation of Vaccinium floribundum Berries with Lactiplantibacillus plantarum Reduces Oxidative Stress in Endothelial Cells and Modulates Macrophages Function Open
Accumulating evidence suggests that high consumption of natural antioxidants promotes health by reducing oxidative stress and, thus, the risk of developing cardiovascular diseases. Similarly, fermentation of natural compounds with lactic a…
View article: Grape Pomace for Topical Application: Green NaDES Sustainable Extraction, Skin Permeation Studies, Antioxidant and Anti-Inflammatory Activities Characterization in 3D Human Keratinocytes
Grape Pomace for Topical Application: Green NaDES Sustainable Extraction, Skin Permeation Studies, Antioxidant and Anti-Inflammatory Activities Characterization in 3D Human Keratinocytes Open
Food waste is a global problem due to its environmental and economic impact, so there is great demand for the exploitation of new functional applications. The winemaking process leads to an incomplete extraction of high-value compounds, le…
View article: Compact Miniaturized Bioluminescence Sensor Based on Continuous Air-Segmented Flow for Real-Time Monitoring: Application to Bile Salt Hydrolase (BSH) Activity and ATP Detection in Biological Fluids
Compact Miniaturized Bioluminescence Sensor Based on Continuous Air-Segmented Flow for Real-Time Monitoring: Application to Bile Salt Hydrolase (BSH) Activity and ATP Detection in Biological Fluids Open
A simple and versatile continuous air-segmented flow sensor using immobilized luciferase was designed as a general miniaturized platform based on sensitive biochemiluminescence detection. The device uses miniaturized microperistaltic pumps…
View article: Dual lateral flow optical/chemiluminescence immunosensors for the rapid detection of salivary and serum IgA in patients with COVID-19 disease
Dual lateral flow optical/chemiluminescence immunosensors for the rapid detection of salivary and serum IgA in patients with COVID-19 disease Open
View article: Effect of Lactobacillus acidophilus Fermented Broths Enriched with Eruca sativa Seed Extracts on Intestinal Barrier and Inflammation in a Co-Culture System of an Enterohemorrhagic Escherichia coli and Human Intestinal Cells
Effect of Lactobacillus acidophilus Fermented Broths Enriched with Eruca sativa Seed Extracts on Intestinal Barrier and Inflammation in a Co-Culture System of an Enterohemorrhagic Escherichia coli and Human Intestinal Cells Open
Lactic acid bacteria (LAB) “fermentates” confer a beneficial effect on intestinal function. However, the ability of new fermentations to improve LAB broth activity in preventing pathogen-induced intestinal inflammation and barrier dysfunct…
View article: Detoxification of bilirubin and bile acids with intermittent coupled plasmafiltration and adsorption in liver failure (HERCOLE study)
Detoxification of bilirubin and bile acids with intermittent coupled plasmafiltration and adsorption in liver failure (HERCOLE study) Open
View article: Selective chemiluminescent TURN-ON quantitative bioassay and imaging of intracellular hydrogen peroxide in human living cells
Selective chemiluminescent TURN-ON quantitative bioassay and imaging of intracellular hydrogen peroxide in human living cells Open
View article: A challenge in biosensors: Is it better to measure a photon or an electron for ultrasensitive detection?
A challenge in biosensors: Is it better to measure a photon or an electron for ultrasensitive detection? Open
View article: Precision medicine, bioanalytics and nanomaterials: toward a new generation of personalized portable diagnostics
Precision medicine, bioanalytics and nanomaterials: toward a new generation of personalized portable diagnostics Open
The customization of disease treatment focused on genetic, environmental and lifestyle factors of individual patients, including tailored medical decisions and treatments, is identified as precision medicine.
View article: Paper-based smartphone chemosensor for reflectometric on-site total polyphenols quantification in olive oil
Paper-based smartphone chemosensor for reflectometric on-site total polyphenols quantification in olive oil Open
View article: Peptides from Cauliflower By-Products, Obtained by an Efficient, Ecosustainable, and Semi-Industrial Method, Exert Protective Effects on Endothelial Function
Peptides from Cauliflower By-Products, Obtained by an Efficient, Ecosustainable, and Semi-Industrial Method, Exert Protective Effects on Endothelial Function Open
The large amount of cauliflower industry waste represents an unexplored source of bioactive compounds. In this work, peptide hydrolysates from cauliflower leaves were characterized by combined bioanalytical approaches. Twelve peptide fract…
View article: Chemiluminescence-based biosensor for monitoring astronauts’ health status during space missions: Results from the International Space Station
Chemiluminescence-based biosensor for monitoring astronauts’ health status during space missions: Results from the International Space Station Open
View article: Smartphone-based multicolor bioluminescent 3D spheroid biosensors for monitoring inflammatory activity
Smartphone-based multicolor bioluminescent 3D spheroid biosensors for monitoring inflammatory activity Open
View article: SP477HEPATIC REGENERATION WITH COUPLED PLASMAFILTRATION AND ADSORPTION FOR LIVER EXTRACORPOREAL DETOXIFICATION (HERCOLE STUDY)
SP477HEPATIC REGENERATION WITH COUPLED PLASMAFILTRATION AND ADSORPTION FOR LIVER EXTRACORPOREAL DETOXIFICATION (HERCOLE STUDY) Open
View article: Advanced biosensors for monitoring astronauts’ health during long-duration space missions
Advanced biosensors for monitoring astronauts’ health during long-duration space missions Open
View article: The fermentation with lactic acid bacteria further enhances the immunomodulatory and antioxidant properties of a Carica Papaya Linn formulation in comparison with yeast fermentation
The fermentation with lactic acid bacteria further enhances the immunomodulatory and antioxidant properties of a Carica Papaya Linn formulation in comparison with yeast fermentation Open
Background : Dietary supplements of Carica papaya Linn fermented with yeast using a biotechnological process have well recognized positive effects on immunological, hematological, inflammatory, and oxidative stress parameters, utilized a…
View article: Comparative study of the antioxidant and immunomodulant activities between yeast and lab fermented papaya
Comparative study of the antioxidant and immunomodulant activities between yeast and lab fermented papaya Open
Background: Dietary supplements of Carica papaya Linn fermented with yeast using a biotechnological process have well recognized positive effects on immunological, hematological, inflammatory, and oxidative stress parameters, utilized as b…
View article: A novel bioluminescent NanoLuc yeast-estrogen screen biosensor (nanoYES) with a compact wireless camera for effect-based detection of endocrine-disrupting chemicals
A novel bioluminescent NanoLuc yeast-estrogen screen biosensor (nanoYES) with a compact wireless camera for effect-based detection of endocrine-disrupting chemicals Open
View article: Smartphone–based enzymatic biosensor for oral fluid L-lactate detection in one minute using confined multilayer paper reflectometry
Smartphone–based enzymatic biosensor for oral fluid L-lactate detection in one minute using confined multilayer paper reflectometry Open
View article: A new analytical platform based on field-flow fractionation and olfactory sensor to improve the detection of viable and non-viable bacteria in food
A new analytical platform based on field-flow fractionation and olfactory sensor to improve the detection of viable and non-viable bacteria in food Open
View article: Relationship between indocyanine green retention test, decompensation and survival in patients with Child‐Pugh A cirrhosis and portal hypertension
Relationship between indocyanine green retention test, decompensation and survival in patients with Child‐Pugh A cirrhosis and portal hypertension Open
Background & Aims Indocyanine green retention test (ICG‐r15) is a non‐invasive marker of functional hepatic reserve. Among patients with compensated cirrhosis, ICG‐r15 correlates to the degree of portal hypertension (PH); however, its prog…
View article: Progress in chemical luminescence-based biosensors: A critical review
Progress in chemical luminescence-based biosensors: A critical review Open