Patrizia Sucapane
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View article: Network analysis of negative emotions in patients with episodic migraine: need for a multidisciplinary perspective
Network analysis of negative emotions in patients with episodic migraine: need for a multidisciplinary perspective Open
Background Episodic migraine (EM) is the second most prevalent neurological disorder worldwide and is responsible for more disability than all other neurological disorders combined. Triggers for the development of migraine include, stress,…
View article: Staged magnetic resonance-guided focused ultrasound thalamotomy for the treatment of bilateral essential tremor and Parkinson’s disease related tremor: a systematic review and critical appraisal of current knowledge
Staged magnetic resonance-guided focused ultrasound thalamotomy for the treatment of bilateral essential tremor and Parkinson’s disease related tremor: a systematic review and critical appraisal of current knowledge Open
Introduction Essential tremor (ET) and Parkinson’s Disease (PD) are debilitating neurodegenerative disorders characterized by tremor as a predominant symptom, significantly impacting patients’ quality of life. Magnetic Resonance-guided Foc…
View article: Cognitive safety of focused ultrasound thalamotomy for tremor: 1-year follow-up results of the COGNIFUS part 2 study
Cognitive safety of focused ultrasound thalamotomy for tremor: 1-year follow-up results of the COGNIFUS part 2 study Open
Introduction In the COGNitive in Focused UltraSound (COGNIFUS) study, we examined the 6-month cognitive outcomes of patients undergoing MRgFUS thalamotomy. This study endorsed the safety profile of the procedure in terms of cognitive funct…
View article: Early re-emerging tremor after MRgFUS thalamotomy: case–control analysis of procedural and imaging features
Early re-emerging tremor after MRgFUS thalamotomy: case–control analysis of procedural and imaging features Open
Purpose This study aimed to identify possible prognostic factors determining early tremor relapse after Magnetic Resonance guided Focused Ultrasound Surgery (MRgFUS) thalamotomy in patients with essential tremor (ET) and Parkinson’s diseas…
View article: Facial emotion recognition and judgment of affective scenes in Parkinson's disease
Facial emotion recognition and judgment of affective scenes in Parkinson's disease Open
Emotional dysfunctions in Parkinson's disease (PD) remain a controversial issue. While previous investigations showed compromised recognition of expressive faces in PD, no studies evaluated potential deficits in recognizing the emotional v…
View article: Effects of deep brain stimulation of the subthalamic nucleus on patients with Parkinson's disease: a machine-learning voice analysis
Effects of deep brain stimulation of the subthalamic nucleus on patients with Parkinson's disease: a machine-learning voice analysis Open
Introduction Deep brain stimulation of the subthalamic nucleus (STN-DBS) can exert relevant effects on the voice of patients with Parkinson's disease (PD). In this study, we used artificial intelligence to objectively analyze the voices of…
View article: MRgFUS thalamotomy for the treatment of tremor: evaluation of learning curve and operator’s experience impact on the procedural and clinical outcome
MRgFUS thalamotomy for the treatment of tremor: evaluation of learning curve and operator’s experience impact on the procedural and clinical outcome Open
View article: Levodopa Equivalent Dose of Safinamide: A Multicenter, Longitudinal, Case–Control Study
Levodopa Equivalent Dose of Safinamide: A Multicenter, Longitudinal, Case–Control Study Open
Background Effects of dopaminergic medications used to treat Parkinson's disease (PD) may be compared with each other by using conversion factors, calculated as Levodopa equivalent dose (LED). However, current LED proposals on MAO‐B inhibi…
View article: Magnetic Resonance-guided Focused Ultrasound thalamotomy for refractory neuropathic pain: a systematic review and critical appraisal of current knowledge
Magnetic Resonance-guided Focused Ultrasound thalamotomy for refractory neuropathic pain: a systematic review and critical appraisal of current knowledge Open
Background: Magnetic Resonance-guided Focused Ultrasound (MRgFUS) is an innovative therapeutical approach for medically refractory tremor. It is currently under investigation for other neurological diseases including refractory neuropathic…
View article: Cognitive outcomes after focused ultrasound thalamotomy for tremor: Results from the COGNIFUS (COGNitive in Focused UltraSound) study
Cognitive outcomes after focused ultrasound thalamotomy for tremor: Results from the COGNIFUS (COGNitive in Focused UltraSound) study Open
Our study moves a step forward in establishing the cognitive sequelae of MRgFUS thalamotomy and in endorsing effectiveness and safety.
View article: Gene- and Gender-Related Decrease in Serum BDNF Levels in Alzheimer’s Disease
Gene- and Gender-Related Decrease in Serum BDNF Levels in Alzheimer’s Disease Open
Brain-derived neurotrophic factor (BDNF) has a protective role in Alzheimer’s disease (AD). Oxidative stress and inflammatory cytokines are potentially implicated in AD risk. In this study, BDNF was detected in serum of AD and mild cogniti…
View article: Cerebello-Thalamo-Cortical MR Spectroscopy in Patients with Essential Tremor Undergoing MRgFUS Thalamotomy: A Pilot Study
Cerebello-Thalamo-Cortical MR Spectroscopy in Patients with Essential Tremor Undergoing MRgFUS Thalamotomy: A Pilot Study Open
Previous literature studies explored the association between brain neurometabolic changes detected by MR spectroscopy and symptoms in patients with tremor, as well as the outcome after deep brain stimulation (DBS) treatment. The purpose of…
View article: Neurotrophins as Therapeutic Agents for Parkinson’s Disease; New Chances From Focused Ultrasound?
Neurotrophins as Therapeutic Agents for Parkinson’s Disease; New Chances From Focused Ultrasound? Open
Magnetic Resonance–guided Focused Ultrasound (MRgFUS) represents an effective micro-lesioning approach to target pharmaco-resistant tremor, mostly in patients afflicted by essential tremor (ET) and/or Parkinson’s disease (PD). So far, expe…
View article: Comprehensive Evaluation of Factors Affecting Tremor Relapse after MRgFUS Thalamotomy: A Case-Control Study
Comprehensive Evaluation of Factors Affecting Tremor Relapse after MRgFUS Thalamotomy: A Case-Control Study Open
Objective: To identify possible relevant factors contributing to tremor relapse after MRgFUS thalamotomy in patients with essential tremor (ET) and Parkinson’s disease (PD). Methods: We identified patients with tremor relapse from a series…
View article: Comparative evaluation of tractography-based direct targeting and atlas-based indirect targeting of the ventral intermediate (Vim) nucleus in MRgFUS thalamotomy
Comparative evaluation of tractography-based direct targeting and atlas-based indirect targeting of the ventral intermediate (Vim) nucleus in MRgFUS thalamotomy Open
View article: Symptoms of gait and coordination impairment in a patient with COVID-19 interstitial pneumonia
Symptoms of gait and coordination impairment in a patient with COVID-19 interstitial pneumonia Open
View article: Multiparametric evaluation of physical values in trans-cranial talamothomy
Multiparametric evaluation of physical values in trans-cranial talamothomy Open
Poster: ECR 2019 / C-3020 / Multiparametric evaluation of physical values in trans-cranial talamothomy by: L. Panebianco 1, M. V. M. Micelli1, F. Bruno1, A. Catalucci1, M. Varrassi1, F. Arrigoni1, P. Sucapane1, A. Ricci2, C. …
View article: Possible prediction of MRgFUS thalamotomy for tremor treatment outcome based on periprocedural MR imaging findings
Possible prediction of MRgFUS thalamotomy for tremor treatment outcome based on periprocedural MR imaging findings Open
Poster: ECR 2019 / C-3093 / Possible prediction of MRgFUS thalamotomy for tremor treatment outcome based on periprocedural MR imaging findings by: F. Bruno , L. Panebianco, M. V. M. Micelli, F. Arrigoni, A. Catalucci, M. Varrass…
View article: Posterior Reversible Encephalopathy Syndrome Presenting with Atypical Findings: Report of Two Cases
Posterior Reversible Encephalopathy Syndrome Presenting with Atypical Findings: Report of Two Cases Open
Background . Posterior reversible encephalopathy syndrome (PRES) is characterized by a variable association of symptoms including headache, consciousness impairment, visual disturbances, seizures, and focal neurological signs. Treating the…
View article: Neurological involvement of IgG4-related disease: description of a case and review of the literature
Neurological involvement of IgG4-related disease: description of a case and review of the literature Open
IgG4-related disease is a recently discovered pathological entity, histologically characterised by fibrosis and IgG4-positive plasma cell infiltration. This condition may virtually involve every site of the organism, with a various range o…