Paul Bourdon
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View article: A reanalysis of the FDA's benefit-risk assessment of Moderna's mRNA-1273 COVID vaccine stratified not only based on age and sex but also on prior-infection and comorbidity status
A reanalysis of the FDA's benefit-risk assessment of Moderna's mRNA-1273 COVID vaccine stratified not only based on age and sex but also on prior-infection and comorbidity status Open
The United States Food and Drug Administration (FDA) conducted a benefit-risk assessment for Moderna's COVID vaccine mRNA-1273 prior to its full approval, announced 1/31/2022. The FDA's assessment focused on males of ages 18-64 years becau…
View article: Why a major study on myocarditis risk following COVID vaccination should not influence public-health policy
Why a major study on myocarditis risk following COVID vaccination should not influence public-health policy Open
OPINION article Front. Med., 23 March 2023Sec. Infectious Diseases: Pathogenesis and Therapy Volume 10 - 2023 | https://doi.org/10.3389/fmed.2023.1126945
View article: Closed-range posinormal operators and their products
Closed-range posinormal operators and their products Open
We focus on two problems relating to the question of when the product of two posinormal operators is posinormal, giving (1) necessary conditions and sufficient conditions for posinormal operators to have closed range, and (2) sufficient co…
View article: Misleading assertions, unjustified assumptions, and additional limitations of a study by Patone et al., described in the article "Risk of Myocarditis After Sequential Doses of COVID-19 Vaccine and SARS-CoV-2 Infection by Age and Sex"
Misleading assertions, unjustified assumptions, and additional limitations of a study by Patone et al., described in the article "Risk of Myocarditis After Sequential Doses of COVID-19 Vaccine and SARS-CoV-2 Infection by Age and Sex" Open
We describe several shortcomings of a study by Patone et al, whose findings were recently published in the American Heart Association Journal Circulation, including the following: * The study's principal conclusion, as initially stated, be…
View article: Powers of posinormal Hilbert-space operators
Powers of posinormal Hilbert-space operators Open
A bounded linear operator $A$ on a Hilbert space $\mathcal{H}$ is posinormal if there exists a positive operator $P$ such that $AA^{*} = A^{*}PA$. We show that if $A$ is posinormal with closed range, then $A^n$ is posinormal and has closed…
View article: Posinormal Composition Operators on $H^2$
Posinormal Composition Operators on $H^2$ Open
A bounded linear operator $A$ on a Hilbert space is posinormal if there exists a positive operator $P$ such that $AA^{*} = A^{*}PA$. Posinormality of $A$ is equivalent to the inclusion of the range of $A$ in the range of its adjoint $A^*$.…
View article: Bronchoalveolar lavage and plasma Antithrombin and cytokines in inhalation and burn injury: a pilot study.
Bronchoalveolar lavage and plasma Antithrombin and cytokines in inhalation and burn injury: a pilot study. Open
Systemic inflammatory response syndrome (SIRS) is initiated during the acute phase of thermal injury. The objective was to determine the SIRS impact on cytokine and Antithrombin (AT) levels in smoke inhalation and burn injury. This observa…