Paul C. Adamson
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View article: Impact of changing pre‐exposure prophylaxis regimens on retention among men who have sex with men in Hanoi, Vietnam (2020−2023): a cohort study
Impact of changing pre‐exposure prophylaxis regimens on retention among men who have sex with men in Hanoi, Vietnam (2020−2023): a cohort study Open
Introduction We examined the association of pre‐exposure prophylaxis (PrEP) programme retention with the use of daily, event‐driven (ED) or regimen switching reported during follow‐up at any point prior to discontinuation among men who hav…
View article: Variability of antimicrobial susceptibility of commensal Neisseria species supports its use as a marker of excessive antimicrobial consumption – reflections from the results of a four-country study
Variability of antimicrobial susceptibility of commensal Neisseria species supports its use as a marker of excessive antimicrobial consumption – reflections from the results of a four-country study Open
View article: High Prevalence of Ceftriaxone-Resistant <i>Neisseria gonorrhoeae</i> in Hanoi, Vietnam, 2023–2024
High Prevalence of Ceftriaxone-Resistant <i>Neisseria gonorrhoeae</i> in Hanoi, Vietnam, 2023–2024 Open
Ceftriaxone resistance in Neisseria gonorrhoeae is an escalating global health concern, threatening the efficacy of empiric treatment. In the Asia-Pacific region, a rapid surge in ceftriaxone resistance has been observed, primarily associa…
View article: Doxycycline prophylaxis for bacterial sexually transmitted infection prevention in Vietnam: awareness, attitudes and willingness to use among men who have sex with men using HIV-PrEP
Doxycycline prophylaxis for bacterial sexually transmitted infection prevention in Vietnam: awareness, attitudes and willingness to use among men who have sex with men using HIV-PrEP Open
Objectives Doxycycline prophylaxis shows promise for bacterial sexually transmitted infection (STI) prevention, but data primarily come from high-income countries. This study assessed awareness, willingness and factors associated with will…
View article: Doxycycline prophylaxis for sexually transmitted infection prevention in Vietnam: Awareness, attitudes, and willingness to use among men who have sex with men using HIV-PrEP
Doxycycline prophylaxis for sexually transmitted infection prevention in Vietnam: Awareness, attitudes, and willingness to use among men who have sex with men using HIV-PrEP Open
Objectives Doxycycline prophylaxis shows promise for sexually transmitted infection (STI) prevention, but data primarily come from high-income countries. This study assessed awareness, willingness and factors associated with willingness to…
View article: Antimicrobial susceptibilities of oral Neisseria from men on HIV pre-exposure prophylaxis in Hanoi, Vietnam
Antimicrobial susceptibilities of oral Neisseria from men on HIV pre-exposure prophylaxis in Hanoi, Vietnam Open
View article: Routine Testing for Chlamydia and Gonorrhea in an HIV Pre-Exposure Prophylaxis Program in Hanoi, Vietnam: Implications for Low- and Middle-Income Countries
Routine Testing for Chlamydia and Gonorrhea in an HIV Pre-Exposure Prophylaxis Program in Hanoi, Vietnam: Implications for Low- and Middle-Income Countries Open
Objectives To assess the prevalence, anatomical distribution, and correlates of Neisseria gonorrhoeae (NG) and Chlamydia trachomatis (CT) infections within an HIV pre-exposure prophylaxis (PrEP) program in Hanoi, Vietnam. Design Cross-sect…
View article: Ceftriaxone resistance in Neisseria gonorrhoeae associated with the penA-60.001 allele in Hanoi, Viet Nam
Ceftriaxone resistance in Neisseria gonorrhoeae associated with the penA-60.001 allele in Hanoi, Viet Nam Open
View article: Novel lateral flow assay for point-of-care detection of Neisseria gonorrhoeae infection in syndromic management settings: a cross-sectional performance evaluation
Novel lateral flow assay for point-of-care detection of Neisseria gonorrhoeae infection in syndromic management settings: a cross-sectional performance evaluation Open
View article: The Role of Emergency and Primary Care in Combating the Rise of Gonorrhea: Another Purview Paradox?
The Role of Emergency and Primary Care in Combating the Rise of Gonorrhea: Another Purview Paradox? Open
Introduction: Drug-resistant Neisseria gonorrhoeae is an urgent threat to public health. Novel prevention and treatment strategies are emerging, including immunizations, pharmacologic post-exposure prophylaxis, rapid molecular resistance a…
View article: Rapid Diagnosis of <i>Capnocytophaga</i> Infection Made by Peripheral Blood Smear
Rapid Diagnosis of <i>Capnocytophaga</i> Infection Made by Peripheral Blood Smear Open
Dog bites causing local infection are common but seldom lead to life-threatening complications. We present a case of a 52-year-old woman who presented with septic shock and multiorgan failure after sustaining a dog bite. At presentation, s…
View article: Machine learning to predict ceftriaxone resistance using single nucleotide polymorphisms within a global database of <i>Neisseria gonorrhoeae</i> genomes
Machine learning to predict ceftriaxone resistance using single nucleotide polymorphisms within a global database of <i>Neisseria gonorrhoeae</i> genomes Open
Antimicrobial resistance (AMR) in Neisseria gonorrhoeae is an urgent global health issue. Machine learning (ML) is a powerful tool that can aid in identifying mutations and predicting their impact on AMR. The study aimed to use ML models t…
View article: Discovery of a novel sub-lineage of multi-drug resistant Shigella flexneri in Southern California
Discovery of a novel sub-lineage of multi-drug resistant Shigella flexneri in Southern California Open
Clustered outbreaks of multi-drug resistant (MDR) Shigella are on the rise among men who have sex with men (MSM). Identification of MDR sub-lineages is critical for clinical management and public health interventions. Here, we describe a n…
View article: Whole-Genome Sequencing to Predict Antimicrobial Susceptibility Profiles in <i>Neisseria gonorrhoeae</i>
Whole-Genome Sequencing to Predict Antimicrobial Susceptibility Profiles in <i>Neisseria gonorrhoeae</i> Open
Background Neisseria gonorrhoeae is a major public health problem due to increasing incidence and antimicrobial resistance. Genetic markers of reduced susceptibility have been identified; the extent to which those are representative of glo…
View article: Screening for monkeypox virus infections in men who have sex with men in a sexual health clinic in Hanoi, Viet Nam
Screening for monkeypox virus infections in men who have sex with men in a sexual health clinic in Hanoi, Viet Nam Open
In early 2022, an increase in mpox (formerly known as monkeypox) cases occurred in countries without previous mpox infections; there are now more than 81 000 cases reported from 110 countries.1WHO2022 monkeypox outbreak: global trends.http…
View article: A Position Statement on Mpox as a Sexually Transmitted Disease
A Position Statement on Mpox as a Sexually Transmitted Disease Open
The global outbreak of mpox virus constituted an international public health emergency. Reports have highlighted (1) a temporal association between sexual activity and mpox, (2) an association between specific sexual practices and location…
View article: 318. A Pain in the Neck: Cervical Pyomyositis, a Rare Case of Extraintestinal Nontyphoidal Salmonellosis Further Characterized by Whole-Genome Sequencing.
318. A Pain in the Neck: Cervical Pyomyositis, a Rare Case of Extraintestinal Nontyphoidal Salmonellosis Further Characterized by Whole-Genome Sequencing. Open
Background Nontyphoidal salmonellosis (NTS) is the second-most common foodborne illness in the US, but extraintestinal manifestations are rare. We describe a case of sternocleidomastoid (SCM) pyomyositis, a rare entity, caused by Salmonell…
View article: 2211. High prevalence of <i>Chlamydia trachomatis</i> and <i>Neisseria gonorrhoeae</i> identified through routine screening for rectal, pharyngeal, and urethral infections within a HIV pre-exposure prophylaxis program in Hanoi, Vietnam
2211. High prevalence of <i>Chlamydia trachomatis</i> and <i>Neisseria gonorrhoeae</i> identified through routine screening for rectal, pharyngeal, and urethral infections within a HIV pre-exposure prophylaxis program in Hanoi, Vietnam Open
Background Pre-exposure prophylaxis (PrEP) is highly effective for HIV prevention and is being scaled up globally. Patients on PrEP have high rates of bacterial STIs, like Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG), thus rou…
View article: Prevalence and Factors Associated With Antigen Test Positivity Following SARS-CoV-2 Infection Among Health Care Workers in Los Angeles
Prevalence and Factors Associated With Antigen Test Positivity Following SARS-CoV-2 Infection Among Health Care Workers in Los Angeles Open
Surges of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections among health care workers (HCWs) have led to critical staffing shortages. From January 4 to February 4, 2022, we implemented a return-to-work antigen testing…
View article: Endofungal <i>Mycetohabitans rhizoxinica</i> Bacteremia Associated with <i>Rhizopus microsporus</i> Respiratory Tract Infection
Endofungal <i>Mycetohabitans rhizoxinica</i> Bacteremia Associated with <i>Rhizopus microsporus</i> Respiratory Tract Infection Open
We report Mycetohabitans rhizoxinica bacteremia in a 65-year-old woman in California, USA, who was undergoing chimeric antigen receptor T-cell therapy for multiple myeloma. Acute brain infarction and pneumonia developed; Rhizopus microspor…
View article: Machine learning to predict ceftriaxone resistance using single nucleotide polymorphisms within a global database of Neisseria gonorrhoeae genomes
Machine learning to predict ceftriaxone resistance using single nucleotide polymorphisms within a global database of Neisseria gonorrhoeae genomes Open
Antimicrobial resistance in Neisseria gonorrhoeae is an urgent global health issue 1 . Resistance to ceftriaxone, the mainstay of gonorrhea treatment, is increasing 2,3 . Many genotypic mutations are associated with decreased susceptibilit…
View article: Pharyngeal<i>Chlamydia trachomatis</i>in Men Who Have Sex With Men in a Human Immunodeficiency Virus (HIV) Pre-exposure Prophylaxis Program in Hanoi, Vietnam
Pharyngeal<i>Chlamydia trachomatis</i>in Men Who Have Sex With Men in a Human Immunodeficiency Virus (HIV) Pre-exposure Prophylaxis Program in Hanoi, Vietnam Open
to the editor—We read with great interest the report by Evers et al [1], exploring the anatomical site distribution and risk factors for pharyngeal Chlamydia trachomatis infections in a large sample of men who have sex with men (MSM) in Th…
View article: Resistance-Guided Therapy for <i>Neisseria gonorrhoeae</i>
Resistance-Guided Therapy for <i>Neisseria gonorrhoeae</i> Open
Antimicrobial-resistant Neisseria gonorrhoeae infections are a threat to public health. Novel strategies for combating such resistance include the development of molecular assays to facilitate real-time prediction of antimicrobial suscepti…
View article: Prevalence and factors associated with antigen test positivity following SARS-CoV-2 infection among healthcare workers in Los Angeles
Prevalence and factors associated with antigen test positivity following SARS-CoV-2 infection among healthcare workers in Los Angeles Open
Surges of SARS-CoV-2 infections among healthcare workers (HCWs) have led to critical staffing shortages. From January 4 to February 4, 2022, we implemented a return-to-work antigen testing program for HCWs and 870 HCWs participated. Antige…
View article: Reliability of Genetic Alterations in Predicting Ceftriaxone Resistance in Neisseria gonorrhoeae Globally
Reliability of Genetic Alterations in Predicting Ceftriaxone Resistance in Neisseria gonorrhoeae Globally Open
Antimicrobial resistance in Neisseria gonorrhoeae ( N. gonorrhoeae ), the causative agent of gonorrhea, is rising globally. Ceftriaxone is the last remaining antibiotic for empirical treatment of gonorrhea.
View article: Prevalence, Anatomic Distribution, and Correlates of Chlamydia trachomatis and Neisseria gonorrhoeae Infections Among a Cohort of Men Who Have Sex With Men in Hanoi, Vietnam
Prevalence, Anatomic Distribution, and Correlates of Chlamydia trachomatis and Neisseria gonorrhoeae Infections Among a Cohort of Men Who Have Sex With Men in Hanoi, Vietnam Open
Background Neisseria gonorrhoeae (NG) and Chlamydia trachomatis (CT) disproportionately affect men who have sex with men (MSM). Data on the prevalence, anatomical distribution, and correlates of NG and CT infections among MSM in Vietnam ar…
View article: High proportions of rectal and pharyngeal chlamydia and gonorrhoea cases among cisgender men are missed using current CDC screening recommendations
High proportions of rectal and pharyngeal chlamydia and gonorrhoea cases among cisgender men are missed using current CDC screening recommendations Open
Objectives Pharyngeal and rectal Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) infections are often undiagnosed due to their asymptomatic nature. This study aims to determine (1) the prevalence of CT/NG infections by anatomical…
View article: Lower SARS-CoV-2 viral shedding following COVID-19 vaccination among healthcare workers in Los Angeles, California
Lower SARS-CoV-2 viral shedding following COVID-19 vaccination among healthcare workers in Los Angeles, California Open
Among 880 healthcare workers with a positive SARS-CoV-2 test, 264 (30.0%) infections were identified following receipt of at least one vaccine dose. Median SARS-CoV-2 cycle threshold values were highest among individuals receiving two vacc…
View article: Diagnostic Tests for Detecting Chlamydia trachomatis and Neisseria gonorrhoeae in Rectal and Pharyngeal Specimens
Diagnostic Tests for Detecting Chlamydia trachomatis and Neisseria gonorrhoeae in Rectal and Pharyngeal Specimens Open
Chlamydia trachomatis and Neisseria gonorrhoeae are two of the most often reported bacterial infections in the United States. The rectum and oropharynx are important anatomic sites of infection and can contribute to ongoing transmission.
View article: Legislation to Increase Accessibility to Direct-to-Consumer Tests in California
Legislation to Increase Accessibility to Direct-to-Consumer Tests in California Open
Doan, Thuan-Huong Pearl; Adamson, Paul C. MD, MPH; Klausner, Jeffrey D. MD, MPH Author Information