Paul E. Constanthin
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View article: Identification of a T2-hyperintense Perivascular Space in Brain Arteriovenous Malformations
Identification of a T2-hyperintense Perivascular Space in Brain Arteriovenous Malformations Open
The identification of T2-hypertinense perivascular spaces surrounding brain AVMs on neuroradiological imaging may provide insights into the anatomico-radiological relationships of brain AVMs and the surrounding grey and white matter parenc…
View article: Urinary oxytocin secretion after pituitary surgery, early arginine vasopressin deficiency and syndrome of inappropriate antidiuresis
Urinary oxytocin secretion after pituitary surgery, early arginine vasopressin deficiency and syndrome of inappropriate antidiuresis Open
View article: Sex‐Dependent Manifestations of Intracranial Aneurysms
Sex‐Dependent Manifestations of Intracranial Aneurysms Open
Background Intracranial aneurysms (IAs) are more common in women than in men; however, there is still limited knowledge on sex‐dependent differences regarding aneurysm location, multiplicity, rupture risk, risk factors, and histopathology.…
View article: Ultrasound-Targeted Microbubble Destruction Increases BBB Permeability and Promotes Stem Cell–Induced Regeneration of Stroke by Downregulating MMP8
Ultrasound-Targeted Microbubble Destruction Increases BBB Permeability and Promotes Stem Cell–Induced Regeneration of Stroke by Downregulating MMP8 Open
The objective of this study was to evaluate the feasibility, safety, and effectiveness of intravenous stem cell delivery utilizing ultrasound-targeted microbubble destruction (UTMD) in a rat model of middle cerebral artery occlusion (MCAO)…
View article: Ultrasound-targeted microbubble destruction improves the suppression and magnetic resonance imaging of pancreatic cancer with polyethyleneimine nanogels
Ultrasound-targeted microbubble destruction improves the suppression and magnetic resonance imaging of pancreatic cancer with polyethyleneimine nanogels Open
The chemoresistance of pancreatic cancer tumors urgently needs to be addressed. Pancreatic cancer is characterized by an abundant stroma, with significant fibrous connective tissue formation that encapsulates the tumor parenchyma and forms…
View article: Comparison of two segmentation software tools for deep brain stimulation of the subthalamic and ventro-intermedius nuclei
Comparison of two segmentation software tools for deep brain stimulation of the subthalamic and ventro-intermedius nuclei Open
View article: Sex-dependent manifestations of intracranial aneurysms
Sex-dependent manifestations of intracranial aneurysms Open
Background Intracranial aneurysms (IAs) are more common in females than in males, however, there is still very limited knowledge on sex-dependent differences regarding aneurysm location, multiplicity, rupture risk, risk factors and histopa…
View article: Application of virtual reality in neurosurgery: Patient missing. A systematic review
Application of virtual reality in neurosurgery: Patient missing. A systematic review Open
Virtual reality (VR) technology had its earliest developments in the 1970s in the U.S. Air Force and has since evolved into a budding area of scientific research with many practical medical purposes. VR shows a high potential to benefit to…
View article: Use of Virtual Reality to Improve the Quality of the Hospital Stay for Patients in Neurosurgery
Use of Virtual Reality to Improve the Quality of the Hospital Stay for Patients in Neurosurgery Open
Background : Virtual Reality (VR) technologies have numerous beneficial applications for patients during hospitalization (through complete immersion in a virtual, distant place allowing to “escape” from the context of hospitalization). The…
View article: Current state of social media utilization in neurosurgery amongst European Association of Neurosurgical Societies (EANS) member countries
Current state of social media utilization in neurosurgery amongst European Association of Neurosurgical Societies (EANS) member countries Open
View article: Neuropsychological Outcomes after Surgery for Olfactory Groove Meningiomas
Neuropsychological Outcomes after Surgery for Olfactory Groove Meningiomas Open
Background: In recent years, several studies have reported abnormal pre- and postoperative neuropsychological functioning in patients with meningiomas located in the prefrontal cortex (notably the ventromedial region). In the case of olfac…
View article: MRI‐Compatible and Conformal Electrocorticography Grids for Translational Research
MRI‐Compatible and Conformal Electrocorticography Grids for Translational Research Open
Intraoperative electrocorticography (ECoG) captures neural information from the surface of the cerebral cortex during surgeries such as resections for intractable epilepsy and tumors. Current clinical ECoG grids come in evenly spaced, mill…
View article: Increased oxytocin release precedes hyponatremia after pituitary surgery
Increased oxytocin release precedes hyponatremia after pituitary surgery Open
View article: Spine surgery in pregnant women: a multicenter case series and proposition of treatment algorithm
Spine surgery in pregnant women: a multicenter case series and proposition of treatment algorithm Open
Purpose Spinal diseases requiring urgent surgical treatment are rare during pregnancy. Evidence is sparse and data are only available in the form of case reports. Our aim is to provide a comprehensive guide for spinal surgery on pregnant p…
View article: Neuropsychological outcomes after surgery for olfactory groove meningiomas
Neuropsychological outcomes after surgery for olfactory groove meningiomas Open
View article: Injury to the human retrosplenial cortex: Two cases and a review of the literature
Injury to the human retrosplenial cortex: Two cases and a review of the literature Open
Background:The human retrosplenial cortex (RSC) is the cortical region of the parietal lobe that lies directly behind the splenium of the corpus callosum.While recent fundamental research in animal models has suggested a very important rol…
View article: Endogenous erythropoietin signaling regulates migration and laminar positioning of upper-layer neurons in the developing neocortex
Endogenous erythropoietin signaling regulates migration and laminar positioning of upper-layer neurons in the developing neocortex Open
Erythropoietin (EPO), the hypoxia-inducible hematopoietic hormone, has well-established neuroprotective/neurotrophic roles in the developing central nervous system and the therapeutic potential of EPO has been widely explored in clinical s…
View article: Role of erythropoietin signaling in the development and lesion induced plasticity of the mammalian cerebral cortex
Role of erythropoietin signaling in the development and lesion induced plasticity of the mammalian cerebral cortex Open
Paul Constanthin a étudié le rôle méconnu de l'hormone cytokinique érythropoïétine (EPO) durant le développement cortical en utilisant des techniques de gain et perte de fonction, mettant en évidence un rôle majeur de cette protéine lors d…
View article: Case Report on Ruptured Renal Artery Aneurysm
Case Report on Ruptured Renal Artery Aneurysm Open
Renal aneurysms are a rare entity with an incidence of 0.09% of the population. They are often asymptomatic and frequently discovered incidentally during abdominal imaging for unrelated causes. Rupture of renal artery aneurysms is a surgic…
View article: Volvulus of the Small Bowel Due to Malrotation During Pregnancy: A Case-Report
Volvulus of the Small Bowel Due to Malrotation During Pregnancy: A Case-Report Open
Volvulus occurring during pregnancy is a rare complication, still potentially lethal nowadays for both the mother and child due to several, early arising complications.We report here a case of small bowel volvulus in a 28 weeks and 4 days,…
View article: Riedel's thyroiditis
Riedel's thyroiditis Open
View article: Adenosquamous Cell Carcinoma Of The Stomach,18F-FDG PET/CT Diagnosis And Review Of Literature
Adenosquamous Cell Carcinoma Of The Stomach,18F-FDG PET/CT Diagnosis And Review Of Literature Open
Adenosquamous carcinoma of the stomach (ASCS) is extremely rare with less than one hundred cases published in the world literature.It is defined by combined adenocarcima and squamous cells carcinoma of the stomach.ASCS is clinically aggres…
View article: Loss of neuromonitoring signal during bilateral thyroidectomy: no systematic change in operative strategy according to a survey of the French Association of Endocrine Surgeons (AFCE)
Loss of neuromonitoring signal during bilateral thyroidectomy: no systematic change in operative strategy according to a survey of the French Association of Endocrine Surgeons (AFCE) Open
The majority of surgeons continued the operation contralaterally as originally planned despite a loss of IONM signal at the end of the first side.