Paul Henry Láng
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View article: An enzyme activity-based workflow for the identification and characterization of covalent inhibitors
An enzyme activity-based workflow for the identification and characterization of covalent inhibitors Open
The field of covalent drug development has advanced rapidly, offering promising therapeutic potential due to the ability of these drugs to form slowly reversible or irreversible bonds with target proteins, resulting in prolonged pharmacody…
View article: Automation of multiplex biochemical assays to enhance productivity and reduce cycle time using a modular robotic platform
Automation of multiplex biochemical assays to enhance productivity and reduce cycle time using a modular robotic platform Open
Pharmaceutical and biotechnology companies are increasingly being challenged to shorten the cycle time between design, make, test, and analyze (DMTA) compounds. Automation of multiplex assays to obtain multiparameter data on the same robot…
View article: Antigens Varying in Affinity for the B Cell Receptor Induce Differential B Lymphocyte Responses
Antigens Varying in Affinity for the B Cell Receptor Induce Differential B Lymphocyte Responses Open
The B cell receptor (BCR) triggers a variety of biological responses that differ depending upon the properties of the antigen. A panel of M13 phage-displayed peptide ligands with varying affinity for the 3-83 antibody was generated to expl…