Paul L. Plener
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View article: Off-label drug use in children and adolescents treated with antidepressants and antipsychotics: results from a prospective multicenter trial
Off-label drug use in children and adolescents treated with antidepressants and antipsychotics: results from a prospective multicenter trial Open
Background/Objectives Off-label psychopharmacologic medication use is widespread in child and adolescent psychiatry, but little is known about its associated factors. This study aimed to assess frequency and determinants of off-label use o…
View article: Prevalence and risk factors of suicidal ideation amongst unaccompanied young refugees: a machine learning approach
Prevalence and risk factors of suicidal ideation amongst unaccompanied young refugees: a machine learning approach Open
Background Suicidality is a major public health concern worldwide. Evidence on the prevalence and risk factors of suicidality amongst unaccompanied young refugees (UYRs), a population already at risk for mental health disorders, is scarce.…
View article: Effects of a Whole-School Prevention Program Targeting Mental Health and Nonsuicidal Self-Injury in Swedish Adolescents: A Cluster-Randomized Experimental Study with Longitudinal Follow-Up
Effects of a Whole-School Prevention Program Targeting Mental Health and Nonsuicidal Self-Injury in Swedish Adolescents: A Cluster-Randomized Experimental Study with Longitudinal Follow-Up Open
Rising rates of mental health problems and nonsuicidal self-injury (NSSI) among adolescents highlight the need for preventive interventions and the lack of evidence regarding such measures. To date, few studies have investigated school-bas…
View article: Empathy and event related potentials before and after EEG based neurofeedback training in autistic adolescents
Empathy and event related potentials before and after EEG based neurofeedback training in autistic adolescents Open
Autism Spectrum Disorder (ASD) is often characterized by deficits in emotion regulation and empathic abilities, potentially linked to alterations in prefrontal brain regions. This randomized, controlled clinical trial examines the efficacy…
View article: An online vignette experiment on stigma and help-seeking attitudes towards five mental health problems in adolescents and emerging adults
An online vignette experiment on stigma and help-seeking attitudes towards five mental health problems in adolescents and emerging adults Open
Public attitudes vary across mental health (MH) problems. However, research on young people and certain MH conditions is limited. This online-experiment examined stigma and potential help-seeking among 554 adolescents and emerging adults a…
View article: Correction: Water temperature and biological sex influence cold pressor pain in healthy adults: a randomized within-subjects trial
Correction: Water temperature and biological sex influence cold pressor pain in healthy adults: a randomized within-subjects trial Open
[This corrects the article DOI: 10.3389/fphys.2025.1628111.].
View article: Stress reactivity during short trauma narratives in adolescents with post-traumatic stress disorder (PTSD) and complex PTSD
Stress reactivity during short trauma narratives in adolescents with post-traumatic stress disorder (PTSD) and complex PTSD Open
Background: Psychophysiological dysregulations and negative alterations in cognitions and mood characterize post traumatic stress disorder (PTSD) and complex PTSD (C-PTSD), contributing to an increased risk of disorder persistence and chro…
View article: Sex-Specific Differences in Antidepressant and Antipsychotic Treatment Outcomes and Serum Levels in Children and Adolescents
Sex-Specific Differences in Antidepressant and Antipsychotic Treatment Outcomes and Serum Levels in Children and Adolescents Open
Introduction: Sex-specific differences in psychopharmacological treatment have gained increasing attention in adults, with studies showing that women often have higher serum concentrations of psychotropic drugs due to biological difference…
View article: Water temperature and biological sex influence cold pressor pain in healthy adults: a randomized within-subjects trial
Water temperature and biological sex influence cold pressor pain in healthy adults: a randomized within-subjects trial Open
The Cold Pressor Test (CPT) is an established method for evaluating pain perception and stress responses; evidence indicates that females perceive the CPT as more painful than males. However, methodological variations—particularly in water…
View article: Medication Nonadherence in Children and Adolescents with ADHD
Medication Nonadherence in Children and Adolescents with ADHD Open
Objective: Attention-deficit/hyperactivity disorder (ADHD) affects 6–10 % of children and adolescents worldwide. While psychopharmacological treatments effectively reduce symptoms, incomplete adherence is common, diminishing their effectiv…
View article: Neurotherapy for children and adolescents with psychiatric disorders: a state-of-the-art umbrella review of selected clinical methodologies
Neurotherapy for children and adolescents with psychiatric disorders: a state-of-the-art umbrella review of selected clinical methodologies Open
This umbrella review focuses on the clinical application of four neurotherapeutic treatment approaches, namely (1) Electroconvulsive Therapy (ECT), (2) Transcranial Direct Current Stimulation (tDCS), (3) Transcranial Magnetic Stimulation (…
View article: Narrative analysis of interviews conducted with African unaccompanied refugee minors
Narrative analysis of interviews conducted with African unaccompanied refugee minors Open
The results of this study suggest that URM narratives are highly complex and that URM require supportive networks and psychotherapeutic care.
View article: Chronic stress and post-traumatic stress in long COVID: a comparative survey study
Chronic stress and post-traumatic stress in long COVID: a comparative survey study Open
Long COVID (LC) is a prevalent condition among SARS-CoV-2 infections. Yet, in-depth research on adverse stress responses in LC remains limited. The primary aim of this study was to investigate chronic stress and post-traumatic stress due t…
View article: Impact of social media on triggering nonsuicidal self-injury in adolescents: a comparative ambulatory assessment study
Impact of social media on triggering nonsuicidal self-injury in adolescents: a comparative ambulatory assessment study Open
Background Nonsuicidal self-injury (NSSI) is a prevalent and concerning behavior among adolescents, often triggered by negative interpersonal events. As social media is essential in the daily life of adolescents, gaining a better understan…
View article: Characterizing of dropouts in the mental health of refugees and asylum seekers (MEHIRA) study examining the effects of a stepped and collaborative care model – a multicentered rater-blinded randomized controlled trial
Characterizing of dropouts in the mental health of refugees and asylum seekers (MEHIRA) study examining the effects of a stepped and collaborative care model – a multicentered rater-blinded randomized controlled trial Open
Background Dropout from healthcare interventions can negatively affect patients and healthcare providers through impaired trust in the healthcare system and ineffective use of resources. Research on this topic is still largely missing on r…
View article: The STAR collaborative nonsuicidal self-injury study: methods and sample description of the face-to-face sample
The STAR collaborative nonsuicidal self-injury study: methods and sample description of the face-to-face sample Open
Background Nonsuicidal self-injury (NSSI) is highly prevalent in adolescents and young adults worldwide. It is linked to a broad variety of mental disorders and an increased suicide risk. Despite its high prevalence, research on the underl…
View article: Predictors of symptom change in the mental health of refugees and asylum seekers (MEHIRA) study examining the effects of a stepped and collaborative care model – A multicentered rater-blinded randomized controlled trial
Predictors of symptom change in the mental health of refugees and asylum seekers (MEHIRA) study examining the effects of a stepped and collaborative care model – A multicentered rater-blinded randomized controlled trial Open
These outcomes indicate that trauma-related elements as well as content on refugee identity and post-migration social status changes should be included in depression interventions for refugees. Further, recommendations for future outcome p…
View article: A systematic review and meta-analysis on the efficacy of dialectical behavior therapy variants for the treatment of post-traumatic stress disorder
A systematic review and meta-analysis on the efficacy of dialectical behavior therapy variants for the treatment of post-traumatic stress disorder Open
Background: While there are well-established treatments for post-traumatic stress disorder (PTSD), these interventions appear to be less effective for individuals with comorbid borderline personality disorder (BPD) symptoms. Dialectical Be…
View article: Multisession tDCS combined with intrastimulation training improves emotion recognition in adolescents with autism spectrum disorder
Multisession tDCS combined with intrastimulation training improves emotion recognition in adolescents with autism spectrum disorder Open
Previous studies indicate that transcranial direct current stimulation (tDCS) is a promising emerging treatment option for autism spectrum disorder (ASD) and its efficacy could be augmented using concurrent training. However, no intrastimu…
View article: Training approaches for the dissemination of clinical guidelines for NSSI: a quasi-experimental trial
Training approaches for the dissemination of clinical guidelines for NSSI: a quasi-experimental trial Open
Background Non-suicidal self-injury (NSSI) is of high clinical relevance due to its high prevalence and negative long-term implications. In 2016, the German consensus-based clinical guidelines for diagnostic, assessment and treatment of NS…
View article: Attentional Biases and Nonsuicidal Self-Injury Urges in Adolescents
Attentional Biases and Nonsuicidal Self-Injury Urges in Adolescents Open
Importance Nonsuicidal self-injury (NSSI) is a significant clinical concern among adolescents. Exposure to NSSI-related content on social media platforms has been suspected to potentially act as a trigger for NSSI. Objective To use free-vi…