Pauline Lagouge-Roussey
YOU?
Author Swipe
View article: Macrophage expression of P2X7 controls autoimmune uveitis
Macrophage expression of P2X7 controls autoimmune uveitis Open
View article: Splenic monocytes drive pathogenic subretinal inflammation in age-related macular degeneration
Splenic monocytes drive pathogenic subretinal inflammation in age-related macular degeneration Open
Age-related macular degeneration (AMD) is invariably associated with the chronic accumulation of activated mononuclear phagocytes in the subretinal space. The mononuclear phagocytes are composed of microglial cells but also of monocyte-der…
View article: Additional file 1 of Splenic monocytes drive pathogenic subretinal inflammation in age-related macular degeneration
Additional file 1 of Splenic monocytes drive pathogenic subretinal inflammation in age-related macular degeneration Open
Additional file 1: Table S1. Fold Changes (FC) of the 70 genes upregulated between SplMo and BMMo in scRNAseq experiment. The frequency of Ly6C+Mos in the spleen, in sham Eye and SpleX eye represents the percentage of cells with an express…
View article: Omicron BA.1 breakthrough infection drives long-term remodeling of the memory B cell repertoire in vaccinated individuals
Omicron BA.1 breakthrough infection drives long-term remodeling of the memory B cell repertoire in vaccinated individuals Open
Summary How infection by a viral variant showing antigenic drift impacts a preformed mature human memory B cell (MBC) repertoire remains an open question. Here, we studied the MBC response up to 6 months after Omicron BA.1 breakthrough inf…
View article: Human type I IFN deficiency does not impair B cell response to SARS-CoV-2 mRNA vaccination
Human type I IFN deficiency does not impair B cell response to SARS-CoV-2 mRNA vaccination Open
Inborn and acquired deficits of type I interferon (IFN) immunity predispose to life-threatening COVID-19 pneumonia. We longitudinally profiled the B cell response to mRNA vaccination in SARS-CoV-2 naive patients with inherited TLR7, IRF7, …
View article: P2X7-deficiency improves plasticity and cognitive abilities in a mouse model of Tauopathy
P2X7-deficiency improves plasticity and cognitive abilities in a mouse model of Tauopathy Open
View article: The pentose phosphate pathway constitutes a major metabolic hub in pathogenic Francisella
The pentose phosphate pathway constitutes a major metabolic hub in pathogenic Francisella Open
Metabolic pathways are now considered as intrinsic virulence attributes of pathogenic bacteria and thus represent potential targets for antibacterial strategies. Here we focused on the role of the pentose phosphate pathway (PPP) and its co…
View article: The Pentose Phosphate Pathway constitutes a major metabolic hub in pathogenic<i>Francisella</i>
The Pentose Phosphate Pathway constitutes a major metabolic hub in pathogenic<i>Francisella</i> Open
Metabolic pathways are now considered as intrinsic virulence attributes of pathogenic bacteria and hence represent potential targets for anti-bacterial strategies. Here, we addressed the role of the pentose phosphate pathway (PPP) and its …