Pauline Rozier
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View article: Cancer incidence in primary Sjögren's syndrome: Data from the French hospitalization database
Cancer incidence in primary Sjögren's syndrome: Data from the French hospitalization database Open
View article: Lung Fibrosis Is Improved by Extracellular Vesicles from IFNγ-Primed Mesenchymal Stromal Cells in Murine Systemic Sclerosis
Lung Fibrosis Is Improved by Extracellular Vesicles from IFNγ-Primed Mesenchymal Stromal Cells in Murine Systemic Sclerosis Open
Background: Systemic sclerosis (SSc) is a severe autoimmune disease for which mesenchymal stromal cells (MSCs)-based therapy was reported to reduce SSc-related symptoms in pre-clinical studies. Recently, extracellular vesicles released by …
View article: Extracellular Vesicles Are More Potent Than Adipose Mesenchymal Stromal Cells to Exert an Anti-Fibrotic Effect in an In Vitro Model of Systemic Sclerosis
Extracellular Vesicles Are More Potent Than Adipose Mesenchymal Stromal Cells to Exert an Anti-Fibrotic Effect in an In Vitro Model of Systemic Sclerosis Open
Systemic sclerosis (SSc) is a complex disorder resulting from dysregulated interactions between the three main pathophysiological axes: fibrosis, immune dysfunction, and vasculopathy, with no specific treatment available to date. Adipose t…
View article: Mesenchymal stromal cells-derived extracellular vesicles alleviate systemic sclerosis via miR-29a-3p
Mesenchymal stromal cells-derived extracellular vesicles alleviate systemic sclerosis via miR-29a-3p Open
View article: Therapeutic effect of extracellular vesicles derived from mesenchymal stromal cells in systemic sclerosis
Therapeutic effect of extracellular vesicles derived from mesenchymal stromal cells in systemic sclerosis Open
La sclérodermie systémique (ScS) est une maladie rare et sévère, caractérisée par une dérégulation des cellules immunitaires, une fibrose et une vasculopathie généralisées. Aucun traitement curatif n’est validé à ce jour. Les cellules stro…
View article: Effet thérapeutique des vésicules extracellulaires isolées à partir de cellules stromales mésenchymateuses dans la sclérodermie systémique
Effet thérapeutique des vésicules extracellulaires isolées à partir de cellules stromales mésenchymateuses dans la sclérodermie systémique Open
Systemic sclerosis (SSc) is a rare and severe disease characterized by generalized fibrosis, vasculopathy and deregulation of immune cells. No curative treatment is validated to date. Mesenchymal stromal cells (MSCs) are being evaluated in…
View article: Mesenchymal Stem Cell-Derived Extracellular Vesicles: Opportunities and Challenges for Clinical Translation
Mesenchymal Stem Cell-Derived Extracellular Vesicles: Opportunities and Challenges for Clinical Translation Open
Extracellular vesicles (EVs), including exosomes and microvesicles, derived from mesenchymal stem/stromal cells (MSCs) exert similar effects as their parental cells, and are of interest for various therapeutic applications. EVs can act thr…
View article: Mesenchymal Stem Cell Derived Extracellular Vesicles in Aging
Mesenchymal Stem Cell Derived Extracellular Vesicles in Aging Open
Aging is associated with high prevalence of chronic degenerative diseases that take a large part of the increasing burden of morbidities in a growing demographic of elderly people. Aging is a complex process that involves cell autonomous a…
View article: De la fibrogenèse à la fibrose : mécanismes physiopathologiques et présentations cliniques
De la fibrogenèse à la fibrose : mécanismes physiopathologiques et présentations cliniques Open
View article: TGFBI secreted by mesenchymal stromal cells ameliorates osteoarthritis and is detected in extracellular vesicles
TGFBI secreted by mesenchymal stromal cells ameliorates osteoarthritis and is detected in extracellular vesicles Open
View article: Intriguing Relationships Between Cancer and Systemic Sclerosis: Role of the Immune System and Other Contributors
Intriguing Relationships Between Cancer and Systemic Sclerosis: Role of the Immune System and Other Contributors Open
Systemic sclerosis (SSc) is an autoimmune connective tissue disorder, characterized by multisystem involvement, vasculopathy, and fibrosis. An increased risk of malignancy is observed in SSc (including breast and lung cancers), and in a su…
View article: iNOS Activity Is Required for the Therapeutic Effect of Mesenchymal Stem Cells in Experimental Systemic Sclerosis
iNOS Activity Is Required for the Therapeutic Effect of Mesenchymal Stem Cells in Experimental Systemic Sclerosis Open
Objectives: Fibrosis is a hallmark of systemic sclerosis (SSc), an intractable disease where innovative strategies are still being sought. Among novel anti-fibrotic approaches, mesenchymal stromal/stem cell (MSC)-based therapy appea…
View article: Mesenchymal Stem Cells in Systemic Sclerosis: Allogenic or Autologous Approaches for Therapeutic Use?
Mesenchymal Stem Cells in Systemic Sclerosis: Allogenic or Autologous Approaches for Therapeutic Use? Open
Systemic sclerosis (SSc) is a rare autoimmune disease, which is potentially lethal. The physiopathology of the disease is still incompletely elucidated although the role of fibroblasts, endothelial cells (ECs), immune cells. and the enviro…
View article: Fibrosis Development in HOCl-Induced Systemic Sclerosis: A Multistage Process Hampered by Mesenchymal Stem Cells
Fibrosis Development in HOCl-Induced Systemic Sclerosis: A Multistage Process Hampered by Mesenchymal Stem Cells Open
Objectives: Skin fibrosis is the hallmark of systemic sclerosis (SSc) a rare intractable disease with unmet medical need. We previously reported the anti-fibrotic potential of mesenchymal stem cells (MSCs) in a murine model of SSc. …
View article: O021 Mesenchymal stem cell-derived extracellular vesicles: a novel therapeutic option in systemic sclerosis
O021 Mesenchymal stem cell-derived extracellular vesicles: a novel therapeutic option in systemic sclerosis Open