Payam Zahedi
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View article: Melphalan delivery and co-delivery nanoformulations for cancer therapy: A comprehensive review
Melphalan delivery and co-delivery nanoformulations for cancer therapy: A comprehensive review Open
Regardless of the area or the socio-economic status, cancer is currently the second or third prevalent cause of mortality ahead of stroke and coronary heart disease. Melphalan anticancer medication is the phenylalanine derivative of nitrog…
View article: Potential use of a bone tissue engineering scaffold based on electrospun poly (ɛ-caprolactone) - Poly (vinyl alcohol) hybrid nanofibers containing modified cockle shell nanopowder
Potential use of a bone tissue engineering scaffold based on electrospun poly (ɛ-caprolactone) - Poly (vinyl alcohol) hybrid nanofibers containing modified cockle shell nanopowder Open
Today, the construction of scaffolds promoting the differentiation of stem cells is an intelligent innovation that accelerates the differentiation toward the target tissue. The use of calcium and phosphate compounds is capable of elevating…
View article: Experimental Evaluation and Simulation of Myoblast Cell Alignment on the Uv-Irradiated Liquid Crystalline Elastomers as a Versatile Tissue-Engineered Scaffolding Material
Experimental Evaluation and Simulation of Myoblast Cell Alignment on the Uv-Irradiated Liquid Crystalline Elastomers as a Versatile Tissue-Engineered Scaffolding Material Open
View article: Improvement of Intracellular Interactions through Liquid Crystalline Elastomer Scaffolds by the Alteration of Topology
Improvement of Intracellular Interactions through Liquid Crystalline Elastomer Scaffolds by the Alteration of Topology Open
Preparation of inherently bioactive scaffolds has become a challenging issue owing to their complicated synthesis and nonrobust modified cell-actuating property. Liquid crystalline elastomers (LCEs), due to their combined specialties of li…
View article: Red cabbage extract contained sodium alginate/poly (vinyl alcohol) nanofibers as pH-responsive food packaging
Red cabbage extract contained sodium alginate/poly (vinyl alcohol) nanofibers as pH-responsive food packaging Open
Red cabbage extract is a natural pH indicator and its use in polysaccharides is applicable to provide smart food packaging. In this study, we investigated the performance of sodium alginate (SA)/poly (vinyl alcohol) (PVA) nanofibers contai…
View article: Synthesis and Characterization of Bio-nanocomposites Based on Poly(Glycerol Itaconic acid) (PGIt) and Using Poly(ɛ- caprolactone) diol (PCL-diol) as Macro Crosslinkers containing Cloisite Na + to application in Tissue engineering
Synthesis and Characterization of Bio-nanocomposites Based on Poly(Glycerol Itaconic acid) (PGIt) and Using Poly(ɛ- caprolactone) diol (PCL-diol) as Macro Crosslinkers containing Cloisite Na + to application in Tissue engineering Open
Biomaterials are a crucial issue in the field of tissue engineering. Two types of polymeric biomaterials, such as Poly(glycerol Itaconic acid) (PGIt) and Poly(ɛ-caprolactone) diol (PCL-diol), were synthesized by polycondensation and ring o…
View article: Green synthesis of chitosan/polyacrylic acid/graphitic carbon nitride nanocarrier as a potential pH-sensitive system for curcumin delivery to MCF-7 breast cancer cells
Green synthesis of chitosan/polyacrylic acid/graphitic carbon nitride nanocarrier as a potential pH-sensitive system for curcumin delivery to MCF-7 breast cancer cells Open
A novel pH-sensitive nanocarrier containing chitosan (CS), polyacrylic acid (PAA), and graphitic carbon nitride (g-C3N4) was designed via water/oil/water (W/O/W) emulsification to administer curcumin (CUR) drug. g-C
View article: Data from Chemotherapy Dosing Schedule Influences Drug Resistance Development in Ovarian Cancer
Data from Chemotherapy Dosing Schedule Influences Drug Resistance Development in Ovarian Cancer Open
Drug resistance leads to chemotherapy failure and is responsible for the death of a great majority of patients with metastatic, late-stage ovarian cancer. The present study addressed whether changes in the chemotherapy dosing schedule affe…
View article: Supplementary Figure 1 from Chemotherapy Dosing Schedule Influences Drug Resistance Development in Ovarian Cancer
Supplementary Figure 1 from Chemotherapy Dosing Schedule Influences Drug Resistance Development in Ovarian Cancer Open
Supplementary Figure 1 from Chemotherapy Dosing Schedule Influences Drug Resistance Development in Ovarian Cancer
View article: Data from Chemotherapy Dosing Schedule Influences Drug Resistance Development in Ovarian Cancer
Data from Chemotherapy Dosing Schedule Influences Drug Resistance Development in Ovarian Cancer Open
Drug resistance leads to chemotherapy failure and is responsible for the death of a great majority of patients with metastatic, late-stage ovarian cancer. The present study addressed whether changes in the chemotherapy dosing schedule affe…
View article: Supplementary Figure 1 from Chemotherapy Dosing Schedule Influences Drug Resistance Development in Ovarian Cancer
Supplementary Figure 1 from Chemotherapy Dosing Schedule Influences Drug Resistance Development in Ovarian Cancer Open
Supplementary Figure 1 from Chemotherapy Dosing Schedule Influences Drug Resistance Development in Ovarian Cancer
View article: Data from Continuous Docetaxel Chemotherapy Improves Therapeutic Efficacy in Murine Models of Ovarian Cancer
Data from Continuous Docetaxel Chemotherapy Improves Therapeutic Efficacy in Murine Models of Ovarian Cancer Open
Ovarian cancer is known as the silent killer for being asymptomatic until late stages. Current first-line treatment consists of debulking surgery followed by i.v. chemotherapeutics administered intermittently, which leads to insufficient d…
View article: Supplementary Data from Continuous Docetaxel Chemotherapy Improves Therapeutic Efficacy in Murine Models of Ovarian Cancer
Supplementary Data from Continuous Docetaxel Chemotherapy Improves Therapeutic Efficacy in Murine Models of Ovarian Cancer Open
Supplementary Data from Continuous Docetaxel Chemotherapy Improves Therapeutic Efficacy in Murine Models of Ovarian Cancer
View article: Data from Continuous Docetaxel Chemotherapy Improves Therapeutic Efficacy in Murine Models of Ovarian Cancer
Data from Continuous Docetaxel Chemotherapy Improves Therapeutic Efficacy in Murine Models of Ovarian Cancer Open
Ovarian cancer is known as the silent killer for being asymptomatic until late stages. Current first-line treatment consists of debulking surgery followed by i.v. chemotherapeutics administered intermittently, which leads to insufficient d…
View article: Supplementary Data from Continuous Docetaxel Chemotherapy Improves Therapeutic Efficacy in Murine Models of Ovarian Cancer
Supplementary Data from Continuous Docetaxel Chemotherapy Improves Therapeutic Efficacy in Murine Models of Ovarian Cancer Open
Supplementary Data from Continuous Docetaxel Chemotherapy Improves Therapeutic Efficacy in Murine Models of Ovarian Cancer
View article: Synthesis, Solvatochromism and Fluorescence Quenching Studies of Naphthalene Diimide Dye by Nanographene Oxide
Synthesis, Solvatochromism and Fluorescence Quenching Studies of Naphthalene Diimide Dye by Nanographene Oxide Open
A naphthalene diimide dye with two side amine arm was prepared. Uv-Vis and fluorescence spectroscopic techniques studied its photophysical and solvatochromic characteristics in different solvents. Its fluorescence quenching mechanism has b…
View article: Kiwi extract-incorporated poly(ɛ-caprolactone)/cellulose acetate blend nanofibers for healing acceleration of burn wounds
Kiwi extract-incorporated poly(ɛ-caprolactone)/cellulose acetate blend nanofibers for healing acceleration of burn wounds Open
Kiwi extract (KE) including different components such as quercetin, vitamins C and E, and actinides has been known as a debridement agent for burn wounds. In this study, electrospun poly(ɛ-caprolactone)/cellulose acetate blend nanofibers i…
View article: Performance Evaluation of Lawsonia Inermis-Loaded Poly (L-Lactide-Co-D, L-Lactide) Nanofibers as a Bioactive Burn Wound Dressing
Performance Evaluation of Lawsonia Inermis-Loaded Poly (L-Lactide-Co-D, L-Lactide) Nanofibers as a Bioactive Burn Wound Dressing Open
View article: Ovarian Cell Encapsulation in an Enzymatically Crosslinked Silk-Based Hydrogel with Tunable Mechanical Properties
Ovarian Cell Encapsulation in an Enzymatically Crosslinked Silk-Based Hydrogel with Tunable Mechanical Properties Open
An artificial ovary is a promising approach for preserving fertility in prepubertal girls and women who cannot undergo current cryopreservation strategies. However, this approach is in its infancy, due to the possible challenges of creatin…
View article: Osteogenesis enhancement using poly (l-lactide-co-d, l-lactide)/poly (vinyl alcohol) nanofibrous scaffolds reinforced by phospho-calcified cellulose nanowhiskers
Osteogenesis enhancement using poly (l-lactide-co-d, l-lactide)/poly (vinyl alcohol) nanofibrous scaffolds reinforced by phospho-calcified cellulose nanowhiskers Open
View article: A Novel Approach for Development of Intraocular Biodegradable Ranibizumab Implant: A Solution for Stability of Protein Activity
A Novel Approach for Development of Intraocular Biodegradable Ranibizumab Implant: A Solution for Stability of Protein Activity Open
Purpose: Ranibizumab is a monoclonal antibody fragment, targeting all isoforms of vascular endothelial growth factor A (VEGF-A), a protein involved in angiogenesis. It is used to treat age-related macular degeneration (AMD), retinal vein o…
View article: Microfluidic-Assisted Preparation of 5-Fluorouracil-Loaded PLGA Nanoparticles as a Potential System for Colorectal Cancer Therapy
Microfluidic-Assisted Preparation of 5-Fluorouracil-Loaded PLGA Nanoparticles as a Potential System for Colorectal Cancer Therapy Open
This work aims at fabricating 5-fluorouracil (5-FU)-loaded poly (lactic-co-glycolic) acid nanoparticles (PLGA NPs) using a microfluidic (MF) technique, with potential for use in colorectal cancer therapy. In order to achieve 5-FU-loaded NP…
View article: Fabrication of random and aligned-oriented cellulose acetate nanofibers containing betamethasone sodium phosphate: structural and cell biocompatibility evaluations
Fabrication of random and aligned-oriented cellulose acetate nanofibers containing betamethasone sodium phosphate: structural and cell biocompatibility evaluations Open
View article: Strategic Planning in an Academic Radiation Medicine Program
Strategic Planning in an Academic Radiation Medicine Program Open
Background: In this paper, we report on the process of strategic planning in the Radiation Medicine Program (RMP) at the Princess Margaret Cancer Centre. The RMP conducted a strategic planning exercise to ensure that program priorities ref…
View article: Sulfate removal from chlor-alkali brine using nanofiltration: Parameters investigation and optimization via Taguchi design method
Sulfate removal from chlor-alkali brine using nanofiltration: Parameters investigation and optimization via Taguchi design method Open
View article: Microfluidic-aided fabrication of nanoparticles blend based on chitosan for a transdermal multidrug delivery application
Microfluidic-aided fabrication of nanoparticles blend based on chitosan for a transdermal multidrug delivery application Open
View article: Drug release, cell adhesion and wound healing evaluations of electrospun carboxymethyl chitosan/polyethylene oxide nanofibres containing phenytoin sodium and vitamin C
Drug release, cell adhesion and wound healing evaluations of electrospun carboxymethyl chitosan/polyethylene oxide nanofibres containing phenytoin sodium and vitamin C Open
In this work, N, O‐carboxymethyl chitosan (CMCS) samples from virgin chitosan (CS) were synthesised and CMCS/polyethylene oxide (PEO) (50/50) blend nanofibrous samples were successfully electrospun from their aqueous solution. The electros…