Pedro Bullón
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View article: The Role of Oxidative Stress in Periodontitis
The Role of Oxidative Stress in Periodontitis Open
Periodontitis and noncommunicable diseases share an overall inflammatory state often sustained by concomitant oxidative stress as one of the main processes involved. A huge amount of literature supports such a main pathogenic process, whic…
View article: Association of specific nutritional intake with periodontitis
Association of specific nutritional intake with periodontitis Open
Background The present study aimed to evaluate nutritional intake among a group of male patients in the dental clinic with and without periodontal disease to search for associations between nutritional profile and periodontal health. Metho…
View article: Review of: "Periodontal disease in association with Myocardial Infarction with Non-Obstructive Coronary Arteries and Microvascular Coronary Artery Disease"
Review of: "Periodontal disease in association with Myocardial Infarction with Non-Obstructive Coronary Arteries and Microvascular Coronary Artery Disease" Open
View article: Review of: "Periodontal disease in association with Myocardial Infarction with Non-Obstructive Coronary Arteries and Microvascular Coronary Artery Disease"
Review of: "Periodontal disease in association with Myocardial Infarction with Non-Obstructive Coronary Arteries and Microvascular Coronary Artery Disease" Open
View article: Prevalence of undiagnosed diabetes and prediabetes related to periodontitis and its risk factors in elderly individuals
Prevalence of undiagnosed diabetes and prediabetes related to periodontitis and its risk factors in elderly individuals Open
View article: Review of: "Evaluating the clinico-biochemical association between stress and chronic periodontitis by estimation of serum cortisol and serum chromogranin-A levels"
Review of: "Evaluating the clinico-biochemical association between stress and chronic periodontitis by estimation of serum cortisol and serum chromogranin-A levels" Open
View article: Periodontitis and Other Risk Factors Related to Myocardial Infarction and Its Follow-Up
Periodontitis and Other Risk Factors Related to Myocardial Infarction and Its Follow-Up Open
The main issue in the prevention of myocardial infarction (MI) is to reduce risk factors. Periodontal disease is related to cardiovascular disease and both share risk factors. The purpose of this study is to investigate whether periodontit…
View article: Incidence of Peri-Implantitis and Relationship with Different Conditions: A Retrospective Study
Incidence of Peri-Implantitis and Relationship with Different Conditions: A Retrospective Study Open
Articles on the prevalence of peri-implant diseases showed that 90% of peri-implant tissues had some form of inflammatory response and a prevalence of peri-implantitis from 28% to 51% according to various publications. Objective: To provid…
View article: An Olive-Derived Extract 20% Rich in Hydroxytyrosol Prevents β-Amyloid Aggregation and Oxidative Stress, Two Features of Alzheimer Disease, via SKN-1/NRF2 and HSP-16.2 in Caenorhabditis elegans
An Olive-Derived Extract 20% Rich in Hydroxytyrosol Prevents β-Amyloid Aggregation and Oxidative Stress, Two Features of Alzheimer Disease, via SKN-1/NRF2 and HSP-16.2 in Caenorhabditis elegans Open
Olive milling produces olive oil and different by-products, all of them very rich in different bioactive compounds like the phenolic alcohol hydroxytyrosol. The aim of the present study was to investigate the effects of an olive fruit extr…
View article: An oleuropein rich-olive (Olea europaea L.) leaf extract reduces β-amyloid and tau proteotoxicity through regulation of oxidative- and heat shock-stress responses in Caenorhabditis elegans
An oleuropein rich-olive (Olea europaea L.) leaf extract reduces β-amyloid and tau proteotoxicity through regulation of oxidative- and heat shock-stress responses in Caenorhabditis elegans Open
View article: Diabetes Mellitus and Periodontitis Share Intracellular Disorders as the Main Meeting Point
Diabetes Mellitus and Periodontitis Share Intracellular Disorders as the Main Meeting Point Open
Diabetes and periodontitis are two of the most prevalent diseases worldwide that negatively impact the quality of life of the individual suffering from them. They are part of the chronic inflammatory disease group or, as recently mentioned…
View article: Noncomunicable/Aging Diseases with the Perspective of Quantum Physics
Noncomunicable/Aging Diseases with the Perspective of Quantum Physics Open
The leading cause of illness in aging is a group known as Noncommunicable Diseases. There should be some meeting points that modify the cells homeostasis and impaired the cell physiology developing different diseases. Quantum physics studi…
View article: L-arginine ameliorates defective autophagy in GM2 gangliosidoses by mTOR modulation
L-arginine ameliorates defective autophagy in GM2 gangliosidoses by mTOR modulation Open
Tay-Sachs and Sandhoff diseases (GM2 gangliosidosis) are autosomal recessive disorders of lysosomal function that cause fatal and progressive neurodegeneration in infants and young children. Impaired hydrolysis catalysed by β-hexosaminidas…
View article: Sinus Floor Elevation via an Osteotome Technique without Biomaterials
Sinus Floor Elevation via an Osteotome Technique without Biomaterials Open
According to classic Hirschfeld studies, the first teeth to be lost are the first and second maxillary molars. After the teeth are extracted and the alveolar process is developed, the maxillary sinus is reabsorbed and pneumatized with a de…
View article: Influence of Removing or Leaving the Prosthesis after Regenerative Surgery in Peri-Implant Defects: Retrospective Study: 32 Clinical Cases with 2 to 8 Years of Follow-Up
Influence of Removing or Leaving the Prosthesis after Regenerative Surgery in Peri-Implant Defects: Retrospective Study: 32 Clinical Cases with 2 to 8 Years of Follow-Up Open
Purpose: The aim of this retrospective study was to compare the influence of removing or not removing a prosthesis after regenerative surgery on peri-implant defects. Methods: Two different groups were compared (Group 1: removing the prost…
View article: Potential Role of the Mitochondria for the Dermatological Treatment of Papillon-Lefèvre
Potential Role of the Mitochondria for the Dermatological Treatment of Papillon-Lefèvre Open
The Papillon–Lefèvre syndrome (PLS) is a rare autosomal recessive disorder caused by mutations in the Cathepsin C (CTSC) gene, characterized by periodontitis and palmoplantar hyperkeratosis. The main inflammatory deficiencies include oxida…
View article: Honey quality parameters, chemical composition and antimicrobial activity in twelve Ecuadorian stingless bees (Apidae: Apinae: Meliponini) tested against multiresistant human pathogens
Honey quality parameters, chemical composition and antimicrobial activity in twelve Ecuadorian stingless bees (Apidae: Apinae: Meliponini) tested against multiresistant human pathogens Open
View article: Review for "Association between periodontitis and hyperlipidemia: a systematic review and meta‐analysis"
Review for "Association between periodontitis and hyperlipidemia: a systematic review and meta‐analysis" Open
View article: Review for "Association between periodontitis and hyperlipidemia: a systematic review and meta‐analysis"
Review for "Association between periodontitis and hyperlipidemia: a systematic review and meta‐analysis" Open
View article: A Diet Rich in Saturated Fat and Cholesterol Aggravates the Effect of Bacterial Lipopolysaccharide on Alveolar Bone Loss in a Rabbit Model of Periodontal Disease
A Diet Rich in Saturated Fat and Cholesterol Aggravates the Effect of Bacterial Lipopolysaccharide on Alveolar Bone Loss in a Rabbit Model of Periodontal Disease Open
Increasing evidence connects periodontitis with a variety of systemic diseases, including metabolic syndrome, atherosclerosis, and non-alcoholic fatty liver disease (NAFLD). The proposal of this study was to evaluate the role of diets rich…
View article: Quantum Physics, Quantum Biology, Quantum Medicine?
Quantum Physics, Quantum Biology, Quantum Medicine? Open
The leading cause and foremost reason for mortality and morbidity in the world is a group known as Noncommunicable Diseases. The best approach to treat them is to evaluate and control the risk factors. There are shared by all these disease…
View article: Inhibition of the NLRP3 inflammasome prevents ovarian aging
Inhibition of the NLRP3 inflammasome prevents ovarian aging Open
Inflammation is a hallmark of many processes during aging and reproductive physiology, negatively affecting female fertility. The goal of this study was to evaluate the role of the NLRP3 inflammasome in ovarian aging and female fertility. …
View article: Molecular inflammation and oxidative stress are shared mechanisms involved in both myocardial infarction and periodontitis
Molecular inflammation and oxidative stress are shared mechanisms involved in both myocardial infarction and periodontitis Open
Background and Objective Our aims were to improve the understanding of the pathogenic relationship between cardiovascular diseases and periodontitis and to generate new perspectives in the prevention and treatment of acute myocardial infar…
View article: Blockade of the NLRP3 inflammasome improves metabolic health and lifespan in obese mice
Blockade of the NLRP3 inflammasome improves metabolic health and lifespan in obese mice Open
View article: Quantum Physic, Quantum Biology, Quantum Medicine?
Quantum Physic, Quantum Biology, Quantum Medicine? Open
View article: Twenty‐four Months Feeding on Unsaturated Dietary Fats (Virgin Olive, Sunflower, or Fish Oil) Differentially Modulate Gingival Mitochondria in the Rat
Twenty‐four Months Feeding on Unsaturated Dietary Fats (Virgin Olive, Sunflower, or Fish Oil) Differentially Modulate Gingival Mitochondria in the Rat Open
This study investigated the effects of feeding rats for 24 months on different unsaturated fats (virgin olive, sunflower, or fish oil) on gingival mitochondrial ultrastructure and expression of genes related to mitochondrial biology as wel…
View article: Fibroblasts Collagen Production and Histological Alterations in Hereditary Gingival Fibromatosis
Fibroblasts Collagen Production and Histological Alterations in Hereditary Gingival Fibromatosis Open
Hereditary gingival fibromatosis is a disorder for which the etiology remains unknown. We aimed to evaluate the fibroblasts and histological alterations to give new clues. A father and a daughter of a family showing gingival hereditary fib…
View article: A review of the influence of periodontal treatment in systemic diseases
A review of the influence of periodontal treatment in systemic diseases Open
The effects and consequences of periodontal diseases might not be confined to the oral cavity. A great body of evidence has arisen supporting the claim demonstrating an association with several systemic conditions and diseases. With differ…
View article: Nutraceuticals in Periodontal Health: A Systematic Review on the Role of Vitamins in Periodontal Health Maintenance
Nutraceuticals in Periodontal Health: A Systematic Review on the Role of Vitamins in Periodontal Health Maintenance Open
Periodontal disease, a relevant public health problem worldwide, is generally considered a common pathology of elderly people. In this respect, there is agreement about that nutritional status may be a modifying factor in the progression a…
View article: Cardiovascular diseases, NLRP3 inflammasome, and western dietary patterns
Cardiovascular diseases, NLRP3 inflammasome, and western dietary patterns Open