Peggy Perrin
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View article: Impact of SGLT2 inhibitors on blood pressure among kidney transplant recipients: insights from a French multicentric cohort (GREAT ASTRE)
Impact of SGLT2 inhibitors on blood pressure among kidney transplant recipients: insights from a French multicentric cohort (GREAT ASTRE) Open
In KTRs newly treated with SGLT2i, BP decreased at 3 and 6 months, while the overall antihypertensive load, as assessed by DDD, remained stable. Similar effects were observed on HTi. These findings suggest SGLT2i as an effective adjunctive…
View article: Sodium-Glucose Cotransporter-2 Inhibitor in Diabetic and Nondiabetic Renal Transplant Recipients
Sodium-Glucose Cotransporter-2 Inhibitor in Diabetic and Nondiabetic Renal Transplant Recipients Open
View article: Epidemiology of <i>Campylobacter</i> Species Infection in Kidney Transplant Recipients: A Retrospective Multicentric Case-Control Study in France
Epidemiology of <i>Campylobacter</i> Species Infection in Kidney Transplant Recipients: A Retrospective Multicentric Case-Control Study in France Open
Background Campylobacteriosis in kidney transplant recipients (KTRs) is the most common identified bacterial cause of diarrhea. Risk factors in KTRs are unknown. Methods A 10-year multicentric, retrospective 1:1 case-control study was perf…
View article: Assessment of SGLT2 inhibitors' safety and discontinuation causes in patients with advanced chronic kidney disease: insights from a real-world data analysis
Assessment of SGLT2 inhibitors' safety and discontinuation causes in patients with advanced chronic kidney disease: insights from a real-world data analysis Open
To the Editor, Recent randomized trials [1 , 2 ] have demonstrated the renal and cardiovascular benefit of sodium-glucose cotransporter 2 inhibitors ( SGLT2i) in chronic kidney disease ( CKD) patients, irrespective of diabetes status.Howev…
View article: #1940 Plasma complement activation profile in kidney transplant recipients with IgAN supports the importance of the complement alternative pathway in IgAN
#1940 Plasma complement activation profile in kidney transplant recipients with IgAN supports the importance of the complement alternative pathway in IgAN Open
Background and Aims The alternative complement and lectin pathways are key players in IgA nephropathy (IgAN). However, the precise dynamics of complement activation in IgAN remain poorly understood. Non-invasive complement biomarkers are u…
View article: Urinary collagen peptides: Source of markers for bone metabolic processes in kidney transplant recipients
Urinary collagen peptides: Source of markers for bone metabolic processes in kidney transplant recipients Open
Introduction: Kidney transplant recipients (KTRs) are at an increased risk of fractures. Total urinary hydroxyproline excretion served as marker for bone resorption (BR) but was replaced by β‐CrossLaps (CTX), a C‐terminal collagen α‐1(I) c…
View article: Tixagevimab-cilgavimab as an Early Treatment for COVID-19 in Kidney Transplant Recipients
Tixagevimab-cilgavimab as an Early Treatment for COVID-19 in Kidney Transplant Recipients Open
The concomitant use of the monoclonal antibodies (mAbs) tixagevimab-cilgavimab has been originally authorized for pre-exposure prophylaxis of COVID-19.1 Although limited by a weak neutralizing activity,2 tixagevimab-cilgavimab has been the…
View article: 18F-Fluorocholine PET/CT Compared with Current Imaging Procedures for Preoperative Localization of Hyperfunctioning Parathyroids in Patients with Chronic Kidney Disease
18F-Fluorocholine PET/CT Compared with Current Imaging Procedures for Preoperative Localization of Hyperfunctioning Parathyroids in Patients with Chronic Kidney Disease Open
Hyperparathyroidism (HPT) in patients with chronic kidney disease (CKD) includes secondary (sHPT) and tertiary hyperparathyroidism (tHPT). Considering that the role of preoperative imaging in the clinical setting is controversial, in the p…
View article: Management and Outcome After Early Renal Transplant Vein Thrombosis: A French Multicentre Observational Study of Real-Life Practice Over 24 Years
Management and Outcome After Early Renal Transplant Vein Thrombosis: A French Multicentre Observational Study of Real-Life Practice Over 24 Years Open
Early (<14 days) renal transplant vein thrombosis posttransplant (eRVTPT) is a rare but threatening complication. We aimed to assess eRVTPT management and the rate of functional renal transplantation. Of 11,172 adult patients who had un…
View article: Isolated kidney transplantation under lumasiran therapy in primary hyperoxaluria type 1: a report of five cases
Isolated kidney transplantation under lumasiran therapy in primary hyperoxaluria type 1: a report of five cases Open
Primary hyperoxaluria type 1 (PH1) is caused by a mutation in the AGXT gene, encoding the hepatic peroxisomal enzyme alanine-glyoxylate aminotransferase (AGT). Defects in AGT increase glyoxylate and oxalate production, the latter inducing …
View article: Tixagevimab-cilgavimab as an early treatment for COVID-19 in kidney transplant recipients
Tixagevimab-cilgavimab as an early treatment for COVID-19 in kidney transplant recipients Open
Objective This single-center retrospective study evaluated the use of tixagevimab-cilgavimab as an early treatment for COVID-19 in kidney transplant recipients (KTRs) during the omicron wave. Methods KTRs were deemed at high risk for moder…
View article: A rapid decline in the anti–receptor-binding domain of the SARS-CoV-2 spike protein IgG titer in kidney transplant recipients after tixagevimab–cilgavimab administration
A rapid decline in the anti–receptor-binding domain of the SARS-CoV-2 spike protein IgG titer in kidney transplant recipients after tixagevimab–cilgavimab administration Open
View article: Prediction of Vaccine Response and Development of a Personalized Anti-SARS-CoV-2 Vaccination Strategy in Kidney Transplant Recipients: Results from a Large Single-Center Study
Prediction of Vaccine Response and Development of a Personalized Anti-SARS-CoV-2 Vaccination Strategy in Kidney Transplant Recipients: Results from a Large Single-Center Study Open
Kidney transplant recipients (KTRs) displays marked inter-individual variations in magnitude of immune responses to anti-SARS-CoV-2 vaccination. The aim of this large single-center study was to identify the predictive factors for serologic…
View article: Breakthrough COVID-19 cases despite prophylaxis with 150 mg of tixagevimab and 150 mg of cilgavimab in kidney transplant recipients
Breakthrough COVID-19 cases despite prophylaxis with 150 mg of tixagevimab and 150 mg of cilgavimab in kidney transplant recipients Open
View article: The MHC class I MICA gene is a histocompatibility antigen in kidney transplantation
The MHC class I MICA gene is a histocompatibility antigen in kidney transplantation Open
View article: Urinary collagen-derived peptides as sensitive markers for bone resorption and bisphosphonate treatment in kidney transplant patients
Urinary collagen-derived peptides as sensitive markers for bone resorption and bisphosphonate treatment in kidney transplant patients Open
Kidney transplant recipients (KTR) are at increased risk of fractures. Total urinary hydroxyproline excretion used to be a marker for bone resorption (BR) but faded into the background when more specific markers like Beta-CrossLaps (CTX) b…
View article: In Reply to “Letter Regarding ‘Granulomatous Inflammation and Hypercalcemia in Patients With Severe Systemic Oxalosis’”
In Reply to “Letter Regarding ‘Granulomatous Inflammation and Hypercalcemia in Patients With Severe Systemic Oxalosis’” Open
International audience
View article: Infection or a third dose of mRNA vaccine elicits neutralizing antibody responses against SARS-CoV-2 in kidney transplant recipients
Infection or a third dose of mRNA vaccine elicits neutralizing antibody responses against SARS-CoV-2 in kidney transplant recipients Open
Transplant recipients, who receive therapeutic immunosuppression to prevent graft rejection, are characterized by high coronavirus disease 2019 (COVID-19)–related mortality and defective response to vaccines. We observed that previous infe…
View article: Granulomatous Inflammation and Hypercalcemia in Patients With Severe Systemic Oxalosis
Granulomatous Inflammation and Hypercalcemia in Patients With Severe Systemic Oxalosis Open
View article: Comparison of infected and vaccinated transplant recipients highlights the role of Tfh and neutralizing IgG in COVID-19 protection
Comparison of infected and vaccinated transplant recipients highlights the role of Tfh and neutralizing IgG in COVID-19 protection Open
Transplant recipients, which receive therapeutic immunosuppression to prevent graft rejection, are characterized by high COVID-19-related mortality and defective response to vaccines. Having observed that previous infection by SARS-CoV-2 b…
View article: Antibody Response After a Third Dose of the mRNA-1273 SARS-CoV-2 Vaccine in Kidney Transplant Recipients With Minimal Serologic Response to 2 Doses
Antibody Response After a Third Dose of the mRNA-1273 SARS-CoV-2 Vaccine in Kidney Transplant Recipients With Minimal Serologic Response to 2 Doses Open
This study examines the antibody responses to a third dose (100 μg) of the mRNA-1273 SARS-CoV-2 vaccine among kidney transplant recipients in France who had not responded to 2 doses of the vaccine.
View article: Strong antibody response after a first dose of a SARS-CoV-2 mRNA-based vaccine in kidney transplant recipients with a previous history of COVID-19
Strong antibody response after a first dose of a SARS-CoV-2 mRNA-based vaccine in kidney transplant recipients with a previous history of COVID-19 Open
View article: Gross hematuria following SARS-CoV-2 vaccination in patients with IgA nephropathy
Gross hematuria following SARS-CoV-2 vaccination in patients with IgA nephropathy Open
View article: COVID-19 in a kidney transplant recipient treated with eculizumab for atypical hemolytic uremic syndrome: a case report
COVID-19 in a kidney transplant recipient treated with eculizumab for atypical hemolytic uremic syndrome: a case report Open
View article: Low immunization rates among kidney transplant recipients who received 2 doses of the mRNA-1273 SARS-CoV-2 vaccine
Low immunization rates among kidney transplant recipients who received 2 doses of the mRNA-1273 SARS-CoV-2 vaccine Open
View article: Weak anti–SARS-CoV-2 antibody response after the first injection of an mRNA COVID-19 vaccine in kidney transplant recipients
Weak anti–SARS-CoV-2 antibody response after the first injection of an mRNA COVID-19 vaccine in kidney transplant recipients Open
View article: SARS-Cov-2 Seroprevalence in a French Kidney Transplant Center Located Within a “High-risk” Zone
SARS-Cov-2 Seroprevalence in a French Kidney Transplant Center Located Within a “High-risk” Zone Open
Background. Data on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) seroprevalence in kidney transplant recipients (KTRs) remain rare. We sought to shed further light on this issue by conducting a single-center study in a kidn…
View article: Weak anti-SARS-CoV-2 antibody response after the first injection of an mRNA COVID-19 vaccine in kidney transplant recipients
Weak anti-SARS-CoV-2 antibody response after the first injection of an mRNA COVID-19 vaccine in kidney transplant recipients Open
Data concerning the anti-SARS-CoV-2 antibody response after mRNA COVID-19 vaccine in kidney transplant recipients (KTRs) are currently lacking. Here, we sought to examine this issue by analyzing the serological response observed in 241 KTR…
View article: Subcutaneous Casirivimab/Imdevimab (Ronapreve™) Injections for Covid-19 Prophylaxis in Kidney Transplant Recipients
Subcutaneous Casirivimab/Imdevimab (Ronapreve™) Injections for Covid-19 Prophylaxis in Kidney Transplant Recipients Open
View article: Persistence of SARS-CoV-2 antibodies in kidney transplant recipients
Persistence of SARS-CoV-2 antibodies in kidney transplant recipients Open