Peggy Provent
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View article: Abstract 1825: Pharmacological evaluation of bioconjugated trastuzumab using the AbYlinkTM regio-selective conjugation technology in gastric cancer expressing HER2+
Abstract 1825: Pharmacological evaluation of bioconjugated trastuzumab using the AbYlinkTM regio-selective conjugation technology in gastric cancer expressing HER2+ Open
Purpose/introduction: Bioconjugation is a critical step in the development of Antibody Drug Conjugates with two main strategies dominating the field. One approach employs covalent chemistry to randomly bind a drug to the accessible Lysines…