Pei‐Gen Xiao
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View article: Pharmacophylogenetic insights into Scutellaria strigillosa Hemsl.: chloroplast genome and untargeted metabolomics, quantitative analysis and antibacterial analysis
Pharmacophylogenetic insights into Scutellaria strigillosa Hemsl.: chloroplast genome and untargeted metabolomics, quantitative analysis and antibacterial analysis Open
Scutellaria strigillosa Hemsl., known for its traditional use in Chinese herbal medicine, is valued for heat-clearing and detoxifying, promoting diuresis, reducing swelling, alleviating pain, and preventing miscarriage. Despite its histori…
View article: Exploring new therapeutic potential of five commonly used Pteris medicinal plants through pharmaphylogenomics and network pharmacology
Exploring new therapeutic potential of five commonly used Pteris medicinal plants through pharmaphylogenomics and network pharmacology Open
View article: Applications and challenges of DNA barcoding in rapid radiation groups: Rhodiola (Crassulaceae) as a case study
Applications and challenges of DNA barcoding in rapid radiation groups: Rhodiola (Crassulaceae) as a case study Open
ITS2 and psbA-trnH barcodes can identify monophyletic groups represented by R. crenulata. However, for non-monophyletic species, it is necessary to collect as many samples as possible and combine them with multiple markers fo…
View article: Phylogenetic and spatial patterns of herbal medicine compounds: Which medicinal plants are phytochemically characterized?
Phylogenetic and spatial patterns of herbal medicine compounds: Which medicinal plants are phytochemically characterized? Open
These results provide new dimensions and perspectives in the context of pharmacophylogeny for perceiving and evaluating research trends and flashpoints in medicinal phytochemistry.
View article: Comparative chloroplast genomes: insights into the identification and phylogeny of rapid radiation genus Rhodiola
Comparative chloroplast genomes: insights into the identification and phylogeny of rapid radiation genus Rhodiola Open
Rhodiola L. is a genus exhibiting rapid radiation and represents a typical case for studying plastid gene adaptation in species that spread from high altitudes to low altitudes. In this study, 23 samples of 18 Rhodiola species were collect…
View article: Rhizosphere microbial markers (micro-markers): A new physical examination indicator for traditional Chinese medicines
Rhizosphere microbial markers (micro-markers): A new physical examination indicator for traditional Chinese medicines Open
View article: A Novel Bacillus-Shaped Coni Zif-Mxene@Mwcnt Cc Electrochemical Sensor for Sensitive Detection of Salidroside
A Novel Bacillus-Shaped Coni Zif-Mxene@Mwcnt Cc Electrochemical Sensor for Sensitive Detection of Salidroside Open
View article: Transcriptome-wide analysis of PIP reductase gene family identified a phenylpropene synthase crucial for the biosynthesis of dibenzocyclooctadiene lignans in Schisandra chinensis
Transcriptome-wide analysis of PIP reductase gene family identified a phenylpropene synthase crucial for the biosynthesis of dibenzocyclooctadiene lignans in Schisandra chinensis Open
Phenylpropenes, such as isoeugenol and eugenol, are produced as defend compounds, floral attractants, and flavor constituents by phenylpropene synthases belonging to the PIP reductase family. Moreover, isoeugenol is proposed to be involved…
View article: Comprehensive comparison of different parts of Paeonia ostii, a food-medicine plant, based on untargeted metabolomics, quantitative analysis, and bioactivity analysis
Comprehensive comparison of different parts of Paeonia ostii, a food-medicine plant, based on untargeted metabolomics, quantitative analysis, and bioactivity analysis Open
Introduction Paeonia ostii T. Hong & J.X. Zhang (s.s.) (Chinese name, Fengdan) is a widely cultivated food-medicine plant in China, in which root bark, seed kernels, and flowers are utilized for their medicinal and edible values. Howev…
View article: Conservation Tillage in Medicinal Plant Cultivation in China: What, Why, and How
Conservation Tillage in Medicinal Plant Cultivation in China: What, Why, and How Open
Ecological cultivation is a promising regime for medicinal plant production. For a long time, unreasonable farming methods have threatened soil health and medicinal agriculture and restricted the sustainable development of ecological agric…
View article: Investigating the chemical profile of Rheum lhasaense and its main ingredient of piceatannol-3′-O-β-D-glucopyranoside on ameliorating cognitive impairment
Investigating the chemical profile of Rheum lhasaense and its main ingredient of piceatannol-3′-O-β-D-glucopyranoside on ameliorating cognitive impairment Open
Rheum lhasaense A. J. Li et P. K. Hsiao, a stout herb plant from the Polygonaceae, is a typical Tibetan folk herb with heat-clearing and detoxifying effects, but does not have the typical laxative effect compared with other rhubarb plants.…
View article: Bibliometric Study of Adaptogens in Dermatology: Pharmacophylogeny, Phytochemistry, and Pharmacological Mechanisms
Bibliometric Study of Adaptogens in Dermatology: Pharmacophylogeny, Phytochemistry, and Pharmacological Mechanisms Open
The plant adaptogens can repair the skin barrier and maintain skin homeostasis by regulating the skin HPA-like axis, influencing the oxidative stress pathway to inhibit inflammation, and regulating the extracellular matrix (ECM) components…
View article: Editorial: Plant-derived natural compounds in drug discovery: The prism perspective between plant phylogeny, chemical composition, and medicinal efficacy
Editorial: Plant-derived natural compounds in drug discovery: The prism perspective between plant phylogeny, chemical composition, and medicinal efficacy Open
EDITORIAL article Front. Plant Sci., 07 October 2022Sec. Plant Metabolism and Chemodiversity Volume 13 - 2022 | https://doi.org/10.3389/fpls.2022.1042695
View article: Novel active compounds and the anti-diabetic mechanism of mulberry leaves
Novel active compounds and the anti-diabetic mechanism of mulberry leaves Open
Mulberry ( Morus alba L.) leaves have long been considered beneficial in traditional Chinese medicine to treat infectious and internal diseases. Recently studies have discovered that the mulberry leaf’s total flavonoids (MLF) display excel…
View article: Anti-asthmatic fraction screening and mechanisms prediction of Schisandrae Sphenantherae Fructus based on a combined approach
Anti-asthmatic fraction screening and mechanisms prediction of Schisandrae Sphenantherae Fructus based on a combined approach Open
Objective: Schisandrae Sphenantherae Fructus (SSF) is a traditional Chinese medicine used to treat coughs and pulmonary inflammatory diseases. However, the pharmacodynamic material basis and mechanisms for SSF in asthma treatment remain un…
View article: Mining Therapeutic Efficacy from Treasure Chest of Biodiversity and Chemodiversity: Pharmacophylogeny of Ranunculales Medicinal Plants
Mining Therapeutic Efficacy from Treasure Chest of Biodiversity and Chemodiversity: Pharmacophylogeny of Ranunculales Medicinal Plants Open
View article: Plant metabolomics: a new strategy and tool for quality evaluation of Chinese medicinal materials
Plant metabolomics: a new strategy and tool for quality evaluation of Chinese medicinal materials Open
View article: Research progress of Chinese herbal medicine compounds and their bioactivities: Fruitful 2020
Research progress of Chinese herbal medicine compounds and their bioactivities: Fruitful 2020 Open
Traditional Chinese medicines (TCMs) have continued to be a treasure trove. The study of chemodiversity and versatility of bioactivities has always been an important content of pharmacophylogeny. There is amazing progress in the discovery …
View article: The Neuroprotective Effects of Coreopsis tinctoria and Its Mechanism: Interpretation of Network Pharmacological and Experimental Data
The Neuroprotective Effects of Coreopsis tinctoria and Its Mechanism: Interpretation of Network Pharmacological and Experimental Data Open
Background: Coreopsis tinctoria Nutt. (CT), an annual herb in the genus Coreopsis , is an important traditional medicine to be used for antidiabetes and antioxidation. Objective: The antioxidant compounds from CT may affect mitochondrial f…
View article: Distribution patterns and industry planning of commonly used traditional Chinese medicinal plants in China
Distribution patterns and industry planning of commonly used traditional Chinese medicinal plants in China Open
Medicinal plants are the primary material basis for disease prevention and treatment in traditional Chinese medicine (TCM). The conservation and sustainable utilization of these medicinal plants is critical for the development of the TCM i…
View article: Cross-Cultural Ethnobotanical Assembly as a New Tool for Understanding Medicinal and Culinary Values–The Genus Lycium as A Case Study
Cross-Cultural Ethnobotanical Assembly as a New Tool for Understanding Medicinal and Culinary Values–The Genus Lycium as A Case Study Open
Ethnobotanical knowledge is indispensable for the conservation of global biological integrity, and could provide irreplaceable clues for bioprospecting aiming at new food crops and medicines. This biocultural diversity requires a comprehen…
View article: Genome sizes of four important medicinal species in Kadsura by flow cytometry
Genome sizes of four important medicinal species in Kadsura by flow cytometry Open
View article: A Bibliometrics Analysis of Metformin Development From 1980 to 2019
A Bibliometrics Analysis of Metformin Development From 1980 to 2019 Open
Metformin, the first-line oral blood glucose-lowering agent to manage type 2 diabetes, has gained growing popularity on both clinical application and basic research since early 1980s. A thorough and systematic knowledge map of metformin is…
View article: The Utility of Electrochemical Systems in Microbial Degradation of Polycyclic Aromatic Hydrocarbons: Discourse, Diversity and Design
The Utility of Electrochemical Systems in Microbial Degradation of Polycyclic Aromatic Hydrocarbons: Discourse, Diversity and Design Open
Polycyclic aromatic hydrocarbons (PAHs), especially high molecular weight PAHs, are carcinogenic and mutagenic organic compounds that are difficult to degrade. Microbial remediation is a popular method for the PAH removal in diverse enviro…
View article: Target RNA modification for epigenetic drug repositioning in neuroblastoma: computational omics proximity between repurposing drug and disease
Target RNA modification for epigenetic drug repositioning in neuroblastoma: computational omics proximity between repurposing drug and disease Open
RNA modifications modulate most steps of gene expression. However, little is known about its role in neuroblastoma (NBL) and the inhibitors targeting it. We analyzed the RNA-seq (n=122) and CNV data (n=78) from NBL patients in Therapeutica…
View article: Pharmaceutical resource discovery from traditional medicinal plants: Pharmacophylogeny and pharmacophylogenomics
Pharmaceutical resource discovery from traditional medicinal plants: Pharmacophylogeny and pharmacophylogenomics Open
The worldwide botanical and medicinal culture diversity are astonishing and constitute a Pierian spring for innovative drug R&D. Here, the latest awareness and the perspectives of pharmacophylogeny and pharmacophylogenomics, as well as the…
View article: Acteoside From Ligustrum robustum (Roxb.) Blume Ameliorates Lipid Metabolism and Synthesis in a HepG2 Cell Model of Lipid Accumulation
Acteoside From Ligustrum robustum (Roxb.) Blume Ameliorates Lipid Metabolism and Synthesis in a HepG2 Cell Model of Lipid Accumulation Open
We aimed to ascertain the mechanism underlying the effects of acteoside (ACT) from Ligustrum robustum (Roxb.) Blume (Oleaceae) on lipid metabolism and synthesis. ACT, a water-soluble phenylpropanoid glycoside, is the most abundant a…
View article: A Comprehensive Comparative Study for the Authentication of the Kadsura Crude Drug
A Comprehensive Comparative Study for the Authentication of the Kadsura Crude Drug Open
The stems and roots of Kadsura species have been used as the folk medicine in Traditional Chinese medicine (TCM) and have good traditional efficacy and medicinal application with a long history. Among these species, K. coccinea…
View article: Metabolomic profiling reveals effects of marein on energy metabolism in HepG2 cells
Metabolomic profiling reveals effects of marein on energy metabolism in HepG2 cells Open
Previous studies have suggested that Coreopsis tinctoria improves insulin resistance in rats fed with high-fat diet. But little is known about the antidiabetic effects of marein which is the main component of C. tinctoria . This study inve…
View article: Anemone medicinal plants: ethnopharmacology, phytochemistry and biology
Anemone medicinal plants: ethnopharmacology, phytochemistry and biology Open
The Ranunculaceae genus Anemone (order Ranunculales), comprising more than 150 species, mostly herbs, has long been used in folk medicine and worldwide ethnomedicine. Various medicinal compounds have been found in Anemone pla…