Hsin-Pei Wang
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View article: Correction: Lacosamide Is a Novel Drug That Improves AGTPBP1 Knockout-Mediated Impairment of Neuronal and Dopaminergic Function
Correction: Lacosamide Is a Novel Drug That Improves AGTPBP1 Knockout-Mediated Impairment of Neuronal and Dopaminergic Function Open
View article: Long-Term Influence of Pediatric Long COVID Syndrome on Visual Perception and Neuropsychiatric Symptoms
Long-Term Influence of Pediatric Long COVID Syndrome on Visual Perception and Neuropsychiatric Symptoms Open
Neuropsychiatric symptoms, impaired visual perception, and gray matter volume differences are evident in pediatric long COVID cases. The severity of neuropsychiatric symptoms during the acute phase may predict the degree of chronic-phase b…
View article: Lacosamide Is a Novel Drug That Improves AGTPBP1 Knockout-Mediated Impairment of Neuronal and Dopaminergic Function
Lacosamide Is a Novel Drug That Improves AGTPBP1 Knockout-Mediated Impairment of Neuronal and Dopaminergic Function Open
AGTPBP1 regulates microtubule stabilization through post-translational modification of alpha-tubulin. Mutations in the AGTPBP1 gene are associated with clinical phenotypes such as early postnatal cerebellar atrophy, ataxia, spasticity, and…
View article: Applying machine learning to assist in the morphometric assessment of brain arteriolosclerosis through automation
Applying machine learning to assist in the morphometric assessment of brain arteriolosclerosis through automation Open
Objective quantification of brain arteriolosclerosis remains an area of ongoing refinement in neuropathology, with current methods primarily utilizing semi-quantitative scales completed through manual histological examination. These approa…
View article: The neuropathological landscape of small vessel disease and Lewy pathology in a cohort of Hispanic and non-Hispanic White decedents with Alzheimer disease
The neuropathological landscape of small vessel disease and Lewy pathology in a cohort of Hispanic and non-Hispanic White decedents with Alzheimer disease Open
Cerebrovascular and α-synuclein pathologies are frequently observed alongside Alzheimer disease (AD). The heterogeneity of AD necessitates comprehensive approaches to postmortem studies, including the representation of historically underre…
View article: High incidence of cerebrovascular lesions on magnetic resonance imaging in pediatric COVID-19 during omicron outbreak – A retrospective case series
High incidence of cerebrovascular lesions on magnetic resonance imaging in pediatric COVID-19 during omicron outbreak – A retrospective case series Open
A high proportion of vascular abnormalities was observed in pediatric patients with neurological involvements, suggesting that vascular involvement is an important mechanism of neurological manifestations in omicron variant infection.
View article: Neurological manifestations of SARS-CoV-2 infection in children in Taiwan: A cross-section, multicenter study
Neurological manifestations of SARS-CoV-2 infection in children in Taiwan: A cross-section, multicenter study Open
Neurological complications are common in pediatric COVID-19. Visual hallucination, seizure, behavior change, myoclonic jerk, decreased GCS, and hypoglycemia at admission are the most important warning signs of severe neurological involveme…
View article: The microstructural change of the brain and its clinical severity association in pediatric Tourette syndrome patients
The microstructural change of the brain and its clinical severity association in pediatric Tourette syndrome patients Open
Background Gilles de la Tourette syndrome (GTS) is a prevalent pediatric neurological disorder. Most studies point to abnormalities in the cortico-striato-thalamocortical (CSTC) circuits. Neuroimaging studies have shown GTS’s extensive imp…
View article: The neuropathological landscape of Hispanic and non-Hispanic White decedents with Alzheimer disease
The neuropathological landscape of Hispanic and non-Hispanic White decedents with Alzheimer disease Open
Despite the increasing demographic diversity of the United States’ aging population, there remain significant gaps in post-mortem research investigating the ethnoracial heterogeneity in the neuropathological landscape of Alzheimer Disease …
View article: Successful treatment of acute encephalitis and hepatitis in a child with COVID-19 infection
Successful treatment of acute encephalitis and hepatitis in a child with COVID-19 infection Open
We present the case of a 6-year-old Taiwanese boy with a fulminant course of COVID-19 manifesting as high fever, acute consciousness changes, and status epilepticus. Brain MRI showed restricted diffusion in the bilateral hemisphere. Electr…
View article: Eye motor manifestations in children with neurometabolic disorders
Eye motor manifestations in children with neurometabolic disorders Open
Neurometabolic diseases are complex group of rare neurogenetic disorders, which are difficult to diagnose. Patients may have toxic metabolite accumulation, inadequate energy supply, or neurotransmitter deficiency, resulting in a variety of…
View article: The multimodality neuroimage findings in individuals with Tourette syndrome
The multimodality neuroimage findings in individuals with Tourette syndrome Open
View article: FOXG1-Related Syndrome: From Clinical to Molecular Genetics and Pathogenic Mechanisms
FOXG1-Related Syndrome: From Clinical to Molecular Genetics and Pathogenic Mechanisms Open
Individuals with mutations in forkhead box G1 (FOXG1) belong to a distinct clinical entity, termed “FOXG1-related encephalopathy”. There are two clinical phenotypes/syndromes identified in FOXG1-related encephalopathy, duplications and del…