Peilin Lu
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View article: Structural rather than functional brain alterations that characterize the differences between major depressive disorder and primary insomnia: a comparative meta-analysis
Structural rather than functional brain alterations that characterize the differences between major depressive disorder and primary insomnia: a comparative meta-analysis Open
Common increased resting-state activation in limbic and temporal circuits may underlie overlapping neurobiological mechanisms between MDD and PI and represent potential transdiagnostic phenotypes. Distinct patterns of structural changes in…
View article: Non-obtrusive monitoring of obstructive sleep apnea syndrome based on ballistocardiography: a preliminary study
Non-obtrusive monitoring of obstructive sleep apnea syndrome based on ballistocardiography: a preliminary study Open
Introduction Obstructive sleep apnea syndrome (OSAS) degrades sleep quality and is associated with serious health conditions. Instead of the gold-standard polysomnography requiring complex equipment and expertise, a non-obtrusive device su…
View article: The effect of stored autologous blood transfusion on IL-1, IL-6, TNF-α and liver function recovery in patients undergoing liver cancer surgery
The effect of stored autologous blood transfusion on IL-1, IL-6, TNF-α and liver function recovery in patients undergoing liver cancer surgery Open
The research outcomes showcase that stored autologous blood transfusion can reduce the levels of inflammatory factors after surgery and promote the recovery of liver function;Research suggests important references for further understanding…
View article: Diagnostic value of isolated plasma biomarkers and its combination in neurodegenerative dementias: A multicenter cohort study
Diagnostic value of isolated plasma biomarkers and its combination in neurodegenerative dementias: A multicenter cohort study Open
Our results confirmed the diagnostic performance of individual plasma biomarkers Aβ42/Aβ40, p-tau181, NfL, and GFAP in Chinese dementia patients and noted that a combination of these biomarkers may be more accurate in identifying FTD/PSP p…
View article: Increased apparent blood flow and volume of the choroid plexus in the Alzheimer’s Disease patients
Increased apparent blood flow and volume of the choroid plexus in the Alzheimer’s Disease patients Open
Background Recent works suggested the association between the dysfunctional glymphatic system and Alzheimer's Disease, which shows as alternated cerebrospinal fluid production. It is believed that the choroid plexus is the major site of CS…
View article: Traumatic intracranial aneurysm in blast penetrating brain injury: 1 case report and literature review
Traumatic intracranial aneurysm in blast penetrating brain injury: 1 case report and literature review Open
Objective To analyze our treatment experience of a case of traumatic intracranial aneurysm complicated with blast penetrating brain injury. Methods A case of traumatic brain injury (TBI) wounded by shrapnel was admitted in our department i…
View article: Atrial Fibrillation Detection Based on a Residual CNN Using BCG Signals
Atrial Fibrillation Detection Based on a Residual CNN Using BCG Signals Open
Atrial fibrillation (AF) is the most common arrhythmia and can seriously threaten patient health. Research on AF detection carries important clinical significance. This manuscript proposes an AF detection method based on ballistocardiogram…
View article: Statistical Analysis of the Consistency of HRV Analysis Using BCG or Pulse Wave Signals
Statistical Analysis of the Consistency of HRV Analysis Using BCG or Pulse Wave Signals Open
Ballistocardiography (BCG) is considered a good alternative to HRV analysis with its non-contact and unobtrusive acquisition characteristics. However, consensus about its validity has not yet been established. In this study, 50 healthy sub…
View article: Reversible Splenial Lesion Syndrome with Some Novel Causes and Clinical Manifestations
Reversible Splenial Lesion Syndrome with Some Novel Causes and Clinical Manifestations Open
Objective Reversible splenial lesion syndrome (RESLES) is a clinical radiological syndrome characterized by a reversible lesion of the splenium of the corpus callosum with a decreased apparent diffusion coefficient (ADC) value. The clinica…
View article: Individualized clinical management of patients at risk for Alzheimer's dementia
Individualized clinical management of patients at risk for Alzheimer's dementia Open
Introduction Multidomain intervention for Alzheimer's disease (AD) risk reduction is an emerging therapeutic paradigm. Methods Patients were prescribed individually tailored interventions (education/pharmacologic/nonpharmacologic) and rate…
View article: O4‐06‐04: PRECISION MEDICINE INTERVENTION IN PATIENTS AT RISK FOR ALZHEIMER'S DEMENTIA
O4‐06‐04: PRECISION MEDICINE INTERVENTION IN PATIENTS AT RISK FOR ALZHEIMER'S DEMENTIA Open
This clinical trial investigated the comparative effectiveness of multidomain precision medicine interventions in patients at-risk for Alzheimer's disease (AD) dementia. Patients aged 25–86 were recruited from an AD prevention clinic and c…
View article: Alzheimer's “Prevention” vs. “Risk Reduction”: Transcending Semantics for Clinical Practice
Alzheimer's “Prevention” vs. “Risk Reduction”: Transcending Semantics for Clinical Practice Open
The terms "prevention" and "risk reduction" are often used interchangeably in medicine. There is considerable debate, however, over the use of these terms in describing interventions that aim to preserve cognitive health and/or delay disea…
View article: CJN volume 44 issue 5 Cover and Front matter
CJN volume 44 issue 5 Cover and Front matter Open
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View article: Video Head Impulse Test for Early Diagnosis of Vestibular Neuritis Among Acute Vertigo
Video Head Impulse Test for Early Diagnosis of Vestibular Neuritis Among Acute Vertigo Open
Background: This study assesses the value of the video head impulse test (vHIT) for early diagnosis of vestibular neuritis (VN) among acute vertigo. Methods: Thirty-three cases of vestibular neuritis (VN), 96 patients with other acute vert…