Pei Shen
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View article: Orosomucoid 1 Ameliorates Temporomandibular Joint Osteoarthritis by Maintaining Cartilage Homeostasis
Orosomucoid 1 Ameliorates Temporomandibular Joint Osteoarthritis by Maintaining Cartilage Homeostasis Open
Temporomandibular joint osteoarthritis (TMJOA) is one of the most complex temporomandibular disorders. Cartilage matrix degradation results in the infiltration of nerves, blood vessels, and inflammatory cells, which disrupts chondrocyte fu…
View article: The impact of urbanization on regional carbon sequestration in arid areas: A case study of Altay Region, Xinjiang, China
The impact of urbanization on regional carbon sequestration in arid areas: A case study of Altay Region, Xinjiang, China Open
Scientifically exploring the spatiotemporal variation patterns of carbon storage and accurately identifying its major influencing factors hold practical significance for China to achieve the “dual carbon” goals of peaking carbon emissions …
View article: Calcified apoptotic vesicles from PROCR<sup>+</sup> fibroblasts initiate heterotopic ossification
Calcified apoptotic vesicles from PROCR<sup>+</sup> fibroblasts initiate heterotopic ossification Open
Heterotopic ossification (HO) comprises the abnormal formation of ectopic bone in extraskeletal soft tissue. The factors that initiate HO remain elusive. Herein, we found that calcified apoptotic vesicles (apoVs) led to increased calcifica…
View article: Metabolic profiling of synovial fluid in human temporomandibular joint osteoarthritis
Metabolic profiling of synovial fluid in human temporomandibular joint osteoarthritis Open
Introduction Temporomandibular joint (TMJ) osteoarthritis (OA) is a common TMJ degenerative disease with an unclear mechanism. Synovial fluid (SF), an important component of TMJ, contains various proteins and metabolites that may directly …
View article: Imaging evaluation of disc position and status after temporomandibular joint arthroscopic disc repositioning and suturing surgery
Imaging evaluation of disc position and status after temporomandibular joint arthroscopic disc repositioning and suturing surgery Open
After arthroscopic disc repositioning and suturing surgery for ADD patients, the repositioned disc showed tendency to move forward. 12 to 1 o'clock was optional disc site for repositioning while excessive over-correction was not recommende…
View article: Single-cell RNA sequencing reveals neurovascular-osteochondral network crosstalk during temporomandibular joint osteoarthritis: Pilot study in a human condylar cartilage
Single-cell RNA sequencing reveals neurovascular-osteochondral network crosstalk during temporomandibular joint osteoarthritis: Pilot study in a human condylar cartilage Open
Our study marks the first time scRNA-seq was used to identify the cells and genes in a human TMJ-OA condylar cartilage, and neurovascular-osteochondral network crosstalk during the human TMJ-OA process was demonstrated. Targeting the cross…
View article: Risk factors of temporomandibular joint anterior disc displacement associated with dental malocclusion: a cross-sectional study
Risk factors of temporomandibular joint anterior disc displacement associated with dental malocclusion: a cross-sectional study Open
Objective This study aimed to investigate the risk factors associated with temporomandibular joint (TMJ) anterior disc displacement (ADD) in relation to dental malocclusion. Methods In this cross-sectional study, a clinical examination was…
View article: Efficacy of Arthroscopic Diskopexy on Condylar Growth in Temporomandibular Joint Anterior Disk Displacement: A Randomized Clinical Trial
Efficacy of Arthroscopic Diskopexy on Condylar Growth in Temporomandibular Joint Anterior Disk Displacement: A Randomized Clinical Trial Open
Background: Adolescents with temporomandibular joint (TMJ) anterior disk displacement (ADD) frequently develop dentofacial deformities. It is unknown whether adjunctive arthroscopic diskopexy compared with orthodontic treatment alone incre…
View article: The Relationship between Dental Caries, Bone Mineral Density, and Bone Metabolism among Adolescents
The Relationship between Dental Caries, Bone Mineral Density, and Bone Metabolism among Adolescents Open
Background: Bone development, particularly important during adolescence, can be affected by a variety of factors that can lead to the development of bone diseases such as osteoporosis or fractures. Whether dental caries is related to skele…
View article: Rapid induction and long-term self-renewal of neural crest-derived ectodermal chondrogenic cells from hPSCs
Rapid induction and long-term self-renewal of neural crest-derived ectodermal chondrogenic cells from hPSCs Open
Articular cartilage is highly specific and has limited capacity for regeneration if damaged. Human pluripotent stem cells (hPSCs) have the potential to generate any cell type in the body. Here, we report the dual-phase induction of ectoder…
View article: Prognostic Indicators of Yang’s Arthroscopic Technique for Management of Temporomandibular Joint Anterior Disc Displacement: Part 1- Clinical Predictors.
Prognostic Indicators of Yang’s Arthroscopic Technique for Management of Temporomandibular Joint Anterior Disc Displacement: Part 1- Clinical Predictors. Open
In order to optimize the patient selection for specific treatment modality and to achieve favorable treatment outcomes, prognostic indicators impacting the results are important to analyze. This longitudinal retrospective study aimed to an…
View article: Diagnostic accuracy of synovial chondromatosis of the temporomandibular joint on magnetic resonance imaging
Diagnostic accuracy of synovial chondromatosis of the temporomandibular joint on magnetic resonance imaging Open
The purpose of this study was to evaluate the diagnostic accuracy of magnetic resonance imaging (MRI) for synovial chondromatosis (SC) of the temporomandibular joint (TMJ). In this study, 1415 patients (2109 joints) with temporomandibular …
View article: Kaempferide Prevents Titanium Particle Induced Osteolysis by Suppressing JNK Activation during Osteoclast Formation
Kaempferide Prevents Titanium Particle Induced Osteolysis by Suppressing JNK Activation during Osteoclast Formation Open
Kaempferide (KF) is an O-methylated flavonol, a natural plant extract, which is often found in Kaempferia galanga. It has a variety of effects including anti-carcinogenic, anti-inflammatory, anti-oxidant, anti-bacterial and anti-viral prop…
View article: COMBINED JOINT-JAW-OCCLUSION THERAPY: A NEW THEORY AND OUR PROTOCOL
COMBINED JOINT-JAW-OCCLUSION THERAPY: A NEW THEORY AND OUR PROTOCOL Open
Temporomandibular joint (TMJ) internal derangements, or TMJ disc displacement, is a commonly seen disease among adults, as well as children. It interacts with facial deformities and occlusion etiologically and pathologically, and the treat…
View article: Effectiveness of different surgical modalities in the management of temporomandibular joint ankylosis: a meta-analysis.
Effectiveness of different surgical modalities in the management of temporomandibular joint ankylosis: a meta-analysis. Open
The analysis showed that IPG was more effective and displayed a lower recurrence rate, followed by AR and GA, in treating TMJ ankylosis. Thus, this analysis provides strong evidence supporting IPG as a first-line therapy for TMJ ankylosis.
View article: Case studies on local orthodontic traction by minis-implants before implant rehabilitation.
Case studies on local orthodontic traction by minis-implants before implant rehabilitation. Open
In conclusion local orthodontic traction by mini-implants was a less-invasive and short-term method with favorable effects and less necessary occlusal adjustments.