Peiwu Ding YOU? Author Swipe

Last 10y

Qi Huang Fang improves intestinal barrier function and intestinal microbes in septic mice through NLRP3 inflammasome-mediated cellular pyroptosis Open

Tingting Shu, Jun Zhang, Ruiying Hu, Fang Zhou, Hanyong Li , et al. · 2024

QHF improves intestinal barrier function and gut microbiology in mice via NLRP3 inflammasome-mediated cellular pyroptosis.

Pathological implication of CaMKII in NF-κB pathway and SASP during cardiomyocytes senescence Open

Ting Li, Yidi Meng, Peiwu Ding, Hongfei Wang, Jie Liu , et al. · 2022

Senescence-associated secretory phenotype (SASP) could be developed during heart ageing. But the role of SASP in cardiomyocytes senescence and its molecular mechanism remains undetermined. In this study, we observed elevated Ca²⁺

CaMKII inhibition protects against hyperthyroid arrhythmias and adverse myocardial remodeling Open

Daan Nie, Chaorui Xia, Zhiyu Wang, Peiwu Ding, Yidi Meng , et al. · 2022

Hyperthyroidism can potentiate arrhythmias and cardiac hypertrophy, whereas Ca²⁺/calmodulin-dependent kinase II (CaMKII) promotes maladaptive myocardial remodeling. However, it remains unclear whether CaMKII contributes to the p…

Ca2+/calmodulin-dependent protein kinase II inhibition reduces myocardial fatty acid uptake and oxidation after myocardial infarction Open

Yidi Meng, Peiwu Ding, Hongfei Wang, Xueke Yang, Zhiyu Wang , et al. · 2022

An AMP-activated kinase (AMPK) signaling pathway is activated during myocardial ischemia and promotes cardiac fatty acid (FA) uptake and oxidation. Similarly, the multifunctional Ca²⁺/calmodulin-dependent protein kinase II (CaMK…

Sacubitril/Valsartan Alleviates Experimental Autoimmune Myocarditis by Inhibiting Th17 Cell Differentiation Independently of the NLRP3 Inflammasome Pathway Open

Wei Liang, Baikang Xie, Peiwu Ding, Min Wang, Jing Yuan , et al. · 2021

Sacubitril/valsartan (Sac/Val) is a recently approved drug that is commonly used for treatment of heart failure. Several studies indicated that Sac/Val also regulated the secretion of inflammatory factors. However, the effect and mechanism…

IL-9 Promotes the Development of Deep Venous Thrombosis by Facilitating Platelet Function Open

Yuqian Feng, Miao Yu, Feng Zhu, Shaoshao Zhang, Peiwu Ding , et al. · 2018

The development of deep venous thrombosis (DVT) is a sterile inflammatory process related to cytokines, such as interleukin (IL)-6 or IL-17. IL-9 is a cytokine involved in many inflammatory diseases, including cystic fibrosis, ulcerative c…

B10 Cells Ameliorate the Progression of Lupus Nephritis by Attenuating Glomerular Endothelial Cell Injury Open

Miao Yu, You Seon Song, Mingxin Zhu, Wei Liang, Qi Long , et al. · 2015

Background/Aim: B10 cells are generally considered to inhibit the kidney injury in systemic lupus erythematosus (SLE) mouse models, but recently this function of B10 cells was denied by the lineage-specific deletion of IL-10 from B cells. …