Peng Liang
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View article: Efficacy and safety of tranexamic acid in cardiac surgery: a systematic review and network meta-analysis
Efficacy and safety of tranexamic acid in cardiac surgery: a systematic review and network meta-analysis Open
Background Tranexamic acid (TXA) is recommended for reducing blood loss and transfusion in cardiac surgery. However, there are concerns regarding the safety profile of TXA, especially its proconvulsant effects. We conducted this study to i…
View article: Aging precipitation behavior and strengthening mechanisms of 6061 aluminum alloy with a bimodal heterostructure
Aging precipitation behavior and strengthening mechanisms of 6061 aluminum alloy with a bimodal heterostructure Open
View article: iReDev: A Knowledge-Driven Multi-Agent Framework for Intelligent Requirements Development
iReDev: A Knowledge-Driven Multi-Agent Framework for Intelligent Requirements Development Open
Requirements development is a critical phase as it is responsible for providing a clear understanding of what stakeholders need. It involves collaboration among stakeholders to extract explicit requirements and address potential conflicts,…
View article: Advances in the mechanism of small extracellular vesicles promoting the development of hepatocellular carcinoma through multi-network fusion
Advances in the mechanism of small extracellular vesicles promoting the development of hepatocellular carcinoma through multi-network fusion Open
Hepatocellular carcinoma (HCC) is a highly malignant epithelial tumor characterized by global high incidence and poor clinical prognosis. Radical surgical resection, as the standard treatment for early-stage HCC patients, has been extensiv…
View article: Evaluating the Impact of the Failure Mode and Effects Analysis Nursing Approach on Complications of Chronic Obstructive Pulmonary Disease Patients With Respiratory Failure
Evaluating the Impact of the Failure Mode and Effects Analysis Nursing Approach on Complications of Chronic Obstructive Pulmonary Disease Patients With Respiratory Failure Open
Aims/Background Noninvasive intermittent positive pressure ventilation is a widely used approach for managing Chronic obstructive pulmonary disease (COPD) complicated with respiratory failure. Treatment procedures often result in severe co…
View article: Circulating mucosal-associated invariant T cells predict early neurological deterioration in acute ischemic stroke
Circulating mucosal-associated invariant T cells predict early neurological deterioration in acute ischemic stroke Open
MAIT cell frequency was reduced in AIS patients and may serve as a predictive marker for END. Modulating these cells could be a novel AIS treatment strategy.
View article: Efficacy and safety of remimazolam for sedation of patients with end-stage renal disease: a prospective, randomized controlled clinical trial
Efficacy and safety of remimazolam for sedation of patients with end-stage renal disease: a prospective, randomized controlled clinical trial Open
Background: Procedural sedation for patients with end-stage renal disease (ESRD) is challenging due to impaired renal function, which affects drug metabolism and increases the risk of adverse events. Remimazolam, a novel, ultrashort-acting…
View article: Characterization of neuronal spiking patterns in the medial prefrontal cortex under varied general anesthetics in mice
Characterization of neuronal spiking patterns in the medial prefrontal cortex under varied general anesthetics in mice Open
Purpose The mechanisms underlying reversible unconsciousness induced by general anesthetics remain unclear. This study aimed to investigate the effects of four commonly used anesthetics on neuronal spiking patterns in layer 5 of the medial…
View article: Uptake and correlates of influenza vaccine among older adults residing in rural regions of south China: a cross-sectional study
Uptake and correlates of influenza vaccine among older adults residing in rural regions of south China: a cross-sectional study Open
Background Seasonal influenza continues to pose a substantial public health challenge for older adults residing in rural areas worldwide. Vaccination remains the most efficacious means of preventing influenza. This study aimed to investiga…
View article: Effect of acute hypervolemic hemodilution and fluid restriction on bleeding in hepatectomy: a retrospective cohort study
Effect of acute hypervolemic hemodilution and fluid restriction on bleeding in hepatectomy: a retrospective cohort study Open
BACKGROUND Reducing bleeding in hepatectomy is beneficial to patient prognosis. Restricted fluid infusion based on the low central venous pressure (LCVP) concept is often advocated in hepatectomy to reduce intraoperative bleeding, but its …
View article: Comparative Effectiveness of Minimally Invasive Surgery vs Open Surgery in neuroblastoma
Comparative Effectiveness of Minimally Invasive Surgery vs Open Surgery in neuroblastoma Open
Purpose: To explore the feasibility of minimally invasive surgery（MIS）used in the treatment of neuroblastoma. Methods: Selected NB patients were randomly assigned to the MIS group and the open surgery（OS） group. The operative details, majo…
View article: A novel technique of reverse-sequence endoscopic nipple-sparing mastectomy with direct-to-implant breast reconstruction: medium-term oncological safety outcomes and feasibility of 24-h discharge for breast cancer patients
A novel technique of reverse-sequence endoscopic nipple-sparing mastectomy with direct-to-implant breast reconstruction: medium-term oncological safety outcomes and feasibility of 24-h discharge for breast cancer patients Open
Background: Due to the short operation time and no need for special instruments, reverse-sequence endoscopic nipple-sparing mastectomy (R-E-NSM) with direct-to-implant breast reconstruction (DIBR) has been rapidly becoming popular in the l…
View article: The relationship between long-term exposure to environmental NO2 and HDL levels among middle-aged and older adults in China
The relationship between long-term exposure to environmental NO2 and HDL levels among middle-aged and older adults in China Open
Background In recent years, an increasing number of studies have confirmed that air pollution mixtures can lead to abnormal levels of lipid proteins in the body. With the continuous deepening of research, the specific effects of different …
View article: Uptake and correlates of influenza vaccine among older adults residing in rural regions of China: a cross-sectional study
Uptake and correlates of influenza vaccine among older adults residing in rural regions of China: a cross-sectional study Open
Objectives This study aimed to investigate the extent of influenza vaccine coverage and identify the factors influencing vaccine uptake among older adults in rural regions of China. Design A cross-sectional study utilizing convenience samp…
View article: Correction: Impact of total intravenous anesthesia and total inhalation anesthesia as the anesthesia maintenance approaches on blood glucose level and postoperative complications in patients with type 2 diabetes mellitus: a double-blind, randomized controlled trial
Correction: Impact of total intravenous anesthesia and total inhalation anesthesia as the anesthesia maintenance approaches on blood glucose level and postoperative complications in patients with type 2 diabetes mellitus: a double-blind, randomized controlled trial Open
View article: Posterior percutaneous endoscopic cervical foraminotomy for adjacent 2-level foraminal lesions using a single-incision sliding technique
Posterior percutaneous endoscopic cervical foraminotomy for adjacent 2-level foraminal lesions using a single-incision sliding technique Open
View article: Whether intraoperative hydrogen peroxide irrigation is effective in reducing blood loss and surgical site infection after multilevel posterior lumbar fusion surgery: A prospective case-control study of 2400 patients
Whether intraoperative hydrogen peroxide irrigation is effective in reducing blood loss and surgical site infection after multilevel posterior lumbar fusion surgery: A prospective case-control study of 2400 patients Open
View article: Effectiveness Assessment of Bispectral Index Monitoring Compared with Conventional Monitoring in General Anesthesia: A Systematic Review and Meta‐Analysis
Effectiveness Assessment of Bispectral Index Monitoring Compared with Conventional Monitoring in General Anesthesia: A Systematic Review and Meta‐Analysis Open
Background and Objective . The Bispectral Index (BIS) is utilized to guide the depth of anesthesia monitoring during surgical procedures. However, conflicting results regarding the benefits of BIS for depth of anesthesia monitoring have be…
View article: Percutaneous endoscopic-assisted direct pars repair combined with autograft and percutaneous pedicle screw fixation for the treatment of lumbar spondylolysis
Percutaneous endoscopic-assisted direct pars repair combined with autograft and percutaneous pedicle screw fixation for the treatment of lumbar spondylolysis Open
View article: Acute Pulmonary Edema Following Cardiopulmonary Bypass: A Case Report
Acute Pulmonary Edema Following Cardiopulmonary Bypass: A Case Report Open
Background: Acute pulmonary edema following cardiopulmonary bypass (CPB) is a serious complication, the etiology of which could be classified into two groups: cardiogenic and noncardiogenic. Case presentation: We present a 42-year-old male…
View article: A Case of Asymptomatic Tracheoesophageal Fistula
A Case of Asymptomatic Tracheoesophageal Fistula Open
The tracheoesophageal fistula (TEF) is an abnormal flow between the esophagus and the trachea. Most patients with TEF experience severe symptoms. Asymptomatic TEF is rare. In this case report, a 47-year-old woman planned to undergo orthope…
View article: Chronic remote ischemic conditioning treatment in patients with chronic stable angina (EARLY-MYO-CSA): a randomized, controlled proof-of-concept trial
Chronic remote ischemic conditioning treatment in patients with chronic stable angina (EARLY-MYO-CSA): a randomized, controlled proof-of-concept trial Open
View article: Impact of total intravenous anesthesia and total inhalation anesthesia as the anesthesia maintenance approaches on blood glucose level and postoperative complications in patients with type 2 diabetes mellitus: a double-blind, randomized controlled trial
Impact of total intravenous anesthesia and total inhalation anesthesia as the anesthesia maintenance approaches on blood glucose level and postoperative complications in patients with type 2 diabetes mellitus: a double-blind, randomized controlled trial Open
Background Diabetes mellitus is a prevalent metabolic disease in the world. Previous studies have shown that anesthetics can affect perioperative blood glucose levels which related to adverse clinical outcomes. Few studies have explored th…
View article: The volatile anesthetic isoflurane differentially inhibits voltage-gated sodium channel currents between pyramidal and parvalbumin neurons in the prefrontal cortex
The volatile anesthetic isoflurane differentially inhibits voltage-gated sodium channel currents between pyramidal and parvalbumin neurons in the prefrontal cortex Open
Background How volatile anesthetics work remains poorly understood. Modulations of synaptic neurotransmission are the direct cellular mechanisms of volatile anesthetics in the central nervous system. Volatile anesthetics such as isoflurane…
View article: The contribution of probiotics for the double-edge effect of cefazolin on postoperative neurocognitive disorders by rebalancing the gut microbiota
The contribution of probiotics for the double-edge effect of cefazolin on postoperative neurocognitive disorders by rebalancing the gut microbiota Open
Introduction Emerging data suggest that perioperative gut dysbiosis is prevalent and may be associated with postoperative neurocognitive disorders (PND). Antibiotics and probiotics are key factors influencing the microbiota. Many antibioti…
View article: Postoperative pulmonary complications after sugammadex reversal of neuromuscular blockade: a systematic review and meta-analysis with trial sequential analysis
Postoperative pulmonary complications after sugammadex reversal of neuromuscular blockade: a systematic review and meta-analysis with trial sequential analysis Open
View article: Towards Human-Bot Collaborative Software Architecting with ChatGPT
Towards Human-Bot Collaborative Software Architecting with ChatGPT Open
Architecting software-intensive systems can be a complex process. It deals with the daunting tasks of unifying stakeholders' perspectives, designers' intellect, tool-based automation, pattern-driven reuse, and so on, to sketch a blueprint …
View article: Toll-like receptor 4 signaling pathway in sensory neurons mediates remifentanil-induced postoperative hyperalgesia via transient receptor potential ankyrin 1
Toll-like receptor 4 signaling pathway in sensory neurons mediates remifentanil-induced postoperative hyperalgesia via transient receptor potential ankyrin 1 Open
Background: Remifentanil-induced postoperative hyperalgesia (RIH) refers to a state of hyperalgesia or aggravated pre-existing pain after remifentanil exposure. There has been considerable interest in understanding and preventing RIH. Howe…
View article: Comparison effects of two muscle relaxant strategies on postoperative pulmonary complications in transapical transcatheter aortic valve implantation: a propensity score-matched analysis
Comparison effects of two muscle relaxant strategies on postoperative pulmonary complications in transapical transcatheter aortic valve implantation: a propensity score-matched analysis Open
Background Prior studies have reported conflicting results on the effect of sugammadex on postoperative pulmonary complications (PPCs) and research on this topic in transapical-transcatheter aortic valve implantation (TA-TAVI) was sparse. …
View article: Efficacy and safety of ciprofol vs. propofol for the induction and maintenance of general anaesthesia
Efficacy and safety of ciprofol vs. propofol for the induction and maintenance of general anaesthesia Open
BACKGROUND HSK3486 (ciprofol) is a 2,6-disubstituted phenol derivative that acts like propofol as an agonist at the gamma-aminobutyric acid-A (GABA A ) receptor. OBJECTIVE To investigate the efficacy and safety of HSK3486 for general anaes…