Pengfei Zheng
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View article: Fate of Tebuconazole and Trifloxystrobin in Edible Rose Petals: Storage Stability and Human Health Risk Assessment
Fate of Tebuconazole and Trifloxystrobin in Edible Rose Petals: Storage Stability and Human Health Risk Assessment Open
This study addresses the absence of maximum residue limits (MRLs) for tebuconazole and trifloxystrobin in edible rose petals in China by systematically evaluating the residue behavior and dietary exposure risks of these fungicides. An anal…
View article: FLT3L combined with GM-CSF induced dendritic cells drive broad tumor-specific CD8+ T cell responses and remodel the tumor microenvironment to enhance anti-tumor efficacy
FLT3L combined with GM-CSF induced dendritic cells drive broad tumor-specific CD8+ T cell responses and remodel the tumor microenvironment to enhance anti-tumor efficacy Open
Background Dendritic cells (DCs) play a crucial role in anti-tumor immunity by capturing, processing, and presenting tumor antigens to T cells, making DC-based immunotherapy a promising approach for cancer treatment. However, the most comm…
View article: Recommended dosage and environmental risk assessment of insecticides registered on main pyralid borers in China
Recommended dosage and environmental risk assessment of insecticides registered on main pyralid borers in China Open
This study aims to provide data support for pesticide risk management and scientific use on main pyralid borers. Based on the data registered for controlling nine key borers, active ingredients with high dosages were identified and analyze…
View article: Dissipation, metabolism, processing factors and risk assessment of pesticides in peaches from field cultivation to crisp processing
Dissipation, metabolism, processing factors and risk assessment of pesticides in peaches from field cultivation to crisp processing Open
View article: Harnessing artificial intelligence for brain disease: advances in diagnosis, drug discovery, and closed-loop therapeutics
Harnessing artificial intelligence for brain disease: advances in diagnosis, drug discovery, and closed-loop therapeutics Open
Brain diseases pose a significant global health challenge due to their complexity and the limitations of traditional medical strategies. Recent advancements in artificial intelligence (AI), especially deep learning models like Convolutiona…
View article: Multimodal analysis stratifies genetic susceptibility and reveals the pathogenic mechanism of kidney injury in diabetic nephropathy
Multimodal analysis stratifies genetic susceptibility and reveals the pathogenic mechanism of kidney injury in diabetic nephropathy Open
The genetic etiology of diabetic nephropathy (DN) is masked by inaccurate phenotyping and ethnic disparities. Here, we conduct a stepwise genome-wide association study (GWAS) in the Chinese Han population, using a precise phenotype of biop…
View article: Genomic insights into deleterious mutations and their impact on agronomic traits during pear domestication
Genomic insights into deleterious mutations and their impact on agronomic traits during pear domestication Open
The pear (Pyrus spp.), a perennial fruit tree, is subjected to genetic alterations over decades or even centuries to adapt to complex climatic and cultivation conditions. Genome-wide studies of deleterious mutations remain limited in peren…
View article: Sensitive and portable intelligent detection of imidacloprid in agricultural products using smartphone‐integrated test strips
Sensitive and portable intelligent detection of imidacloprid in agricultural products using smartphone‐integrated test strips Open
The detection rate of imidacloprid (IMI) in agro‐products are increasing annually, posing negative effects on food safety and human health. A sensitive and portable dual‐mode lateral flow immunoassay (LFIA) method, combined with the smartp…
View article: Fabrication of Dual Vertical C-Shaped-Channel Nanosheet FETs via a Novel Integration Process for High-Density, Scalable CMOS Applications
Fabrication of Dual Vertical C-Shaped-Channel Nanosheet FETs via a Novel Integration Process for High-Density, Scalable CMOS Applications Open
View article: Association between alkaline phosphatase to albumin ratio and 28-day mortality among geriatric patients with sepsis: a cohort study
Association between alkaline phosphatase to albumin ratio and 28-day mortality among geriatric patients with sepsis: a cohort study Open
The primary objective of our study was to investigate the relationship between alkaline phosphatase to albumin ratio (APAR) and the risk of 28-day mortality in geriatric patients with sepsis. This was a retrospective cohort study of patien…
View article: The association of phenotypic age acceleration with erectile dysfunction among adult males in the United States: A cross-sectional study based on NHANES 2001-2004 database
The association of phenotypic age acceleration with erectile dysfunction among adult males in the United States: A cross-sectional study based on NHANES 2001-2004 database Open
Objective The purpose of this study is to examine the relationship between phenotypic age acceleration (PhenoAgeAccel) and erectile dysfunction (ED) in US males, utilizing data from the National Health and Nutrition Examination Survey (NHA…
View article: Nonlinear relationship between phenotypic age acceleration and testosterone deficiency in the US population: A cross-sectional NHANES study
Nonlinear relationship between phenotypic age acceleration and testosterone deficiency in the US population: A cross-sectional NHANES study Open
Objective This study aims to assess the relationship between Phenotypic age acceleration (PhenoAgeAccel) and testosterone deficiency (TD) in US male, using National Health and Nutrition Examination Survey (NHANES) data from 2015 to 2016. M…
View article: A soft, ultra-tough and multifunctional artificial muscle for volumetric muscle loss treatment
A soft, ultra-tough and multifunctional artificial muscle for volumetric muscle loss treatment Open
The escalating prevalence of skeletal muscle disorders highlights the critical need for innovative treatments for severe injuries such as volumetric muscle loss. Traditional treatments, such as autologous transplants, are constrained by li…
View article: Investigating unilateral and bilateral motor imagery control using electrocorticography and fMRI in awake craniotomy
Investigating unilateral and bilateral motor imagery control using electrocorticography and fMRI in awake craniotomy Open
Our study highlights the unilateral cerebral cortex's significance in controlling bilateral limb motor imagination, offering new insights into future brain network remodeling in patients with hemiplegia. Additionally, these findings provid…
View article: Questionable accuracy of four ELISA kits in serum Netrin-1 measurement
Questionable accuracy of four ELISA kits in serum Netrin-1 measurement Open
Objectives Altered serum Netrin-1 levels have been widely reported in cancer and other clinical diseases and they are often measured by commercial ELISA kits. However, we found the questionable results using these kits and therefore perfor…
View article: Insights from the neural guidance factor Netrin-1 into neurodegeneration and other diseases
Insights from the neural guidance factor Netrin-1 into neurodegeneration and other diseases Open
Netrin-1 was initially discovered as a neuronal growth cue for axonal guidance, and its functions have later been identified in inflammation, tumorigenesis, neurodegeneration, and other disorders. We have recently found its alterations in …
View article: Quartet protein reference materials and datasets for multi-platform assessment of label-free proteomics
Quartet protein reference materials and datasets for multi-platform assessment of label-free proteomics Open
View article: Safety of SARS-CoV-2 vaccines in patients with myasthenia gravis: a meta-analysis
Safety of SARS-CoV-2 vaccines in patients with myasthenia gravis: a meta-analysis Open
View article: Dissipation, Metabolism, Accumulation, Processing and Risk Assessment of Fluopyram and Trifloxystrobin in Cucumbers and Cowpeas from Cultivation to Consumption
Dissipation, Metabolism, Accumulation, Processing and Risk Assessment of Fluopyram and Trifloxystrobin in Cucumbers and Cowpeas from Cultivation to Consumption Open
Fluopyram and trifloxystrobin are widely used for controlling various plant diseases in cucumbers and cowpeas. However, data on residue behaviors in plant cultivation and food processing are currently lacking. Our results showed that cowpe…
View article: Injectable hydrogel loaded with bilayer microspheres to inhibit angiogenesis and promote cartilage regeneration for repairing growth plate injury
Injectable hydrogel loaded with bilayer microspheres to inhibit angiogenesis and promote cartilage regeneration for repairing growth plate injury Open
Introduction: The repair and regeneration of growth plate injuries using tissue engineering techniques remains a challenge due to large bone bridge formation and low chondrogenic efficiency. Methods: In this study, a bilayer drug-loaded mi…
View article: Expanding individualized therapeutic options via genoproteomics
Expanding individualized therapeutic options via genoproteomics Open
Clinical next-generation sequencing (NGS) tests have enabled treatment recommendations for cancer patients with driver gene mutations. Targeted therapy options for patients without driver gene mutations are currently unavailable. Herein, w…
View article: Transcriptomics-proteomics Integration reveals alternative polyadenylation driving inflammation-related protein translation in patients with diabetic nephropathy
Transcriptomics-proteomics Integration reveals alternative polyadenylation driving inflammation-related protein translation in patients with diabetic nephropathy Open
Background Diabetic nephropathy (DN) is a complex disease involving the upregulation of many inflammation-related proteins. Alternative polyadenylation (APA), a crucial post-transcriptional regulatory mechanism, has been proven to play vit…
View article: Greener and Efficient Synthesis of Dimethyl Carbonate from Co2 and Methanol by Photo-Thermal Catalysis of Zirconium Dioxide
Greener and Efficient Synthesis of Dimethyl Carbonate from Co2 and Methanol by Photo-Thermal Catalysis of Zirconium Dioxide Open
View article: Additional file 6 of Quartet protein reference materials and datasets for multi-platform assessment of label-free proteomics
Additional file 6 of Quartet protein reference materials and datasets for multi-platform assessment of label-free proteomics Open
Additional file 6: Table S5. Dilution of QconCAT proteins.
View article: Additional file 4 of Quartet protein reference materials and datasets for multi-platform assessment of label-free proteomics
Additional file 4 of Quartet protein reference materials and datasets for multi-platform assessment of label-free proteomics Open
Additional file 4: Table S3. Downregulated proteins.
View article: Additional file 3 of Quartet protein reference materials and datasets for multi-platform assessment of label-free proteomics
Additional file 3 of Quartet protein reference materials and datasets for multi-platform assessment of label-free proteomics Open
Additional file 3: Table S2. Upregulated proteins.
View article: Additional file 2 of Quartet protein reference materials and datasets for multi-platform assessment of label-free proteomics
Additional file 2 of Quartet protein reference materials and datasets for multi-platform assessment of label-free proteomics Open
Additional file 2: Table S1. Metadata.
View article: Additional file 8 of Quartet protein reference materials and datasets for multi-platform assessment of label-free proteomics
Additional file 8 of Quartet protein reference materials and datasets for multi-platform assessment of label-free proteomics Open
Additional file 8: Table S7. Targeted peptides.
View article: Additional file 7 of Quartet protein reference materials and datasets for multi-platform assessment of label-free proteomics
Additional file 7 of Quartet protein reference materials and datasets for multi-platform assessment of label-free proteomics Open
Additional file 7: Table S6. Absolute quantification of the Quartet.
View article: Additional file 5 of Quartet protein reference materials and datasets for multi-platform assessment of label-free proteomics
Additional file 5 of Quartet protein reference materials and datasets for multi-platform assessment of label-free proteomics Open
Additional file 5: Table S4. Absolute quantification of the QconCAT proteins.