Peicheng Lu
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View article: Degradation of aflatoxin B1 by a newly isolated bacterium Paraburkholderia sp. MH-1
Degradation of aflatoxin B1 by a newly isolated bacterium Paraburkholderia sp. MH-1 Open
Aflatoxin B1 (AFB1), the most harmful mycotoxin found in food and feed, poses significant global health risks due to its toxic, mutagenic, teratogenic, and carcinogenic effects on both humans and livestock. Bacteria capable of degrading AF…
View article: Nanomedicines for the treatment of genitourinary neoplasms
Nanomedicines for the treatment of genitourinary neoplasms Open
Genitourinary neoplasms, accounting for 20-25 % of all malignant tumors, are associated with high mortality rates and pose significant challenges to clinical treatment. Especially for young patients who have reproductive demands, pharmacot…
View article: <scp>IL</scp>‐4‐<scp>JAK1</scp>‐<scp>STAT6</scp> Pathway Mediates Electroacupuncture's Effect on Microglial <scp>M2</scp> Polarization to Treat Inflammatory Bowel Disease With Comorbid Depression
<span>IL</span>‐4‐<span>JAK1</span>‐<span>STAT6</span> Pathway Mediates Electroacupuncture's Effect on Microglial <span>M2</span> Polarization to Treat Inflammatory Bowel Disease With Comorbid Depression Open
Aims Depression is prevalent in inflammatory bowel disease (IBD) and linked to neuroinflammation. However, the underlying mechanisms remain unclear. Therefore, we investigated the efficacy of electroacupuncture in mice with IBD and depress…
View article: Electroacupuncture Regulates Oxidative Stress-Mediated NLRP3/ASC/Caspase-1 Pathway to Inhibit Microglial Activation: Alleviating Neuroinflammation and Depression in IBD
Electroacupuncture Regulates Oxidative Stress-Mediated NLRP3/ASC/Caspase-1 Pathway to Inhibit Microglial Activation: Alleviating Neuroinflammation and Depression in IBD Open
Electroacupuncture significantly alleviated depressive symptoms in IBD mice by inhibiting oxidative stress and microglial activation in the PFC region, thereby ameliorating the neuroinflammatory environment. The findings can provide new th…
View article: Selection of sciatic nerve injury models: implications for pathogenesis and treatment
Selection of sciatic nerve injury models: implications for pathogenesis and treatment Open
Sciatic nerve injury is one of the most frequent peripheral nerve injuries in the world. The loss of motor and sensory function, along with chronic pain caused by sciatic nerve injury, significantly impacts patients’ quality of life. Howev…
View article: The Role of Complementary and Alternative Therapies in the Regulation of Gut Microbiota
The Role of Complementary and Alternative Therapies in the Regulation of Gut Microbiota Open
The gut microbiota constitutes a complex ecosystem, and its composition and function are intricately linked to human health. Dysbiosis of the gut microbiota is closely associated with the onset and progression of various diseases, includin…
View article: The Role of Gut Microbiota-Derived Trimethylamine N-Oxide in the Pathogenesis and Treatment of Mild Cognitive Impairment
The Role of Gut Microbiota-Derived Trimethylamine N-Oxide in the Pathogenesis and Treatment of Mild Cognitive Impairment Open
Mild cognitive impairment (MCI) represents a transitional stage between normal aging and dementia, often considered critical for dementia prevention. Despite its significance, no effective clinical treatment for MCI has yet been establishe…