Per Lytsy
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View article: Heterogeneity in Blood Pressure Response to 4 Antihypertensive Drugs
Heterogeneity in Blood Pressure Response to 4 Antihypertensive Drugs Open
Importance Hypertension is the leading risk factor for premature death worldwide. Multiple blood pressure–lowering therapies are available but the potential for maximizing benefit by personalized targeting of drug classes is unknown. Objec…
View article: Misinterpretations of P-values and statistical tests persists among researchers and professionals working with statistics and epidemiology
Misinterpretations of P-values and statistical tests persists among researchers and professionals working with statistics and epidemiology Open
Background: The aim was to investigate inferences of statistically significant test results among persons with more or less statistical education and research experience. Methods: A total of 75 doctoral students and 64 statisticians/epidem…
View article: Treatment of Provoked Vulvodynia: A Systematic Review
Treatment of Provoked Vulvodynia: A Systematic Review Open
Background Treatment recommendations for provoked vulvodynia (PVD) are based on clinical experiences and there is a need for systematically summarizing the controlled trials in this field. Aim To provide an overview of randomized controlle…
View article: Factors associated with general practitioners’ contacts with sick-listed patients’ employers: A Swedish nationwide questionnaire study
Factors associated with general practitioners’ contacts with sick-listed patients’ employers: A Swedish nationwide questionnaire study Open
Background: General practitioners’ (GP) contacts with sick-listed patients’ employers have been shown to be of importance for return to work. This study aimed to explore GPs’ contacts with sick-listed patients’ employers and factors associ…
View article: Comparing the Efficacy of Multidisciplinary Assessment and Treatment, or Acceptance and Commitment Therapy, with Treatment as Usual on Health Outcomes in Women on Long-Term Sick Leave—A Randomised Controlled Trial
Comparing the Efficacy of Multidisciplinary Assessment and Treatment, or Acceptance and Commitment Therapy, with Treatment as Usual on Health Outcomes in Women on Long-Term Sick Leave—A Randomised Controlled Trial Open
Background: Chronic pain and mental disorders are common reasons for long term sick leave. The study objective was to evaluate the efficacy of a multidisciplinary assessment and treatment program including acceptance and commitment therapy…
View article: Psychosocial interventions at the workplace, a systematic literature review
Psychosocial interventions at the workplace, a systematic literature review Open
The psychosocial work environment has been shown to be of importance for the health and wellbeing of individuals as well as for the productivity, sickness absence levels, and wellbeing of an organization. The aim was to map the existing kn…
View article: Psychosocial work environmental factors and workplace health, a systematic literature review
Psychosocial work environmental factors and workplace health, a systematic literature review Open
The psychosocial work environment is of importance for the health of individuals and organizations. The aim was to map the existing knowledge, as presented in relevant and well performed systematic reviews, that have investigated associati…
View article: Experiences And Needs Concerning Health Related Information For Newly Arrived Refugees In Sweden
Experiences And Needs Concerning Health Related Information For Newly Arrived Refugees In Sweden Open
Background: Owing to communication challenges and a lack of knowledge about the health care system, refugees may be at risk of having limited health literacy, meaning that they will have problems in achieving, understanding, appraising and…
View article: Experiences and Needs Concerning Health Related Information for Newly Arrived Refugees in Sweden
Experiences and Needs Concerning Health Related Information for Newly Arrived Refugees in Sweden Open
Background Owing to communication challenges and a lack of knowledge about the health care system, refugees may be at risk of having limited health literacy, meaning that they will have problems in achieving, understanding, appraising and …
View article: Experiences And Needs Concerning Health Related Information For Newly Arrived Refugees In Sweden
Experiences And Needs Concerning Health Related Information For Newly Arrived Refugees In Sweden Open
Background Owing to communication challenges and a lack of knowledge about the health care system, refugees may be at risk of having limited health literacy, meaning that they will have problems in achieving, understanding, appraising and …
View article: Effects of apixaban compared with warfarin as gain in event-free time – a novel assessment of the results of the ARISTOTLE trial
Effects of apixaban compared with warfarin as gain in event-free time – a novel assessment of the results of the ARISTOTLE trial Open
Background A novel approach to determine the effect of a treatment is to calculate the delay of event, which estimates the gain of event-free time. The aim of this study was to estimate gains in event-free time for stroke or systemic embol…
View article: Gender differences in treatment with antidepressants during first weeks of a sick-leave spell due to depressive episode
Gender differences in treatment with antidepressants during first weeks of a sick-leave spell due to depressive episode Open
Background The incidence of depression is higher in women; women are more often on sick leave due to depression, and more women than men use antidepressants. The objective of this study was to explore possible gender differences in buying …
View article: Gender differences in healthcare management of depression: aspects of sick leave and treatment with psychoactive drugs in a Swedish setting
Gender differences in healthcare management of depression: aspects of sick leave and treatment with psychoactive drugs in a Swedish setting Open
Purpose: To investigate whether women and men diagnosed with depressive disorder were managed equally in terms of being sick-leave certified and being prescribed psychoactive drugs. Materials and methods: Data from all patients diagnosed w…
View article: Living environment, social support, and informal caregiving are associated with healthcare seeking behaviour and adherence to medication treatment: A cross‐sectional population study
Living environment, social support, and informal caregiving are associated with healthcare seeking behaviour and adherence to medication treatment: A cross‐sectional population study Open
Despite the well-known associations between local environment and health, few studies have focused on environment and healthcare utilisation, for instance healthcare seeking behaviour or adherence. This study was aimed at analysing housing…
View article: <i>P</i> in the right place: Revisiting the evidential value of <i>P</i>‐values
<i>P</i> in the right place: Revisiting the evidential value of <i>P</i>‐values Open
P ‐values are often calculated when testing hypotheses in quantitative settings, and low P ‐values are typically used as evidential measures to support research findings in published medical research. This article reviews old and new argum…
View article: Multidisciplinary Intervention and Acceptance and Commitment Therapy for Return-to-Work and Increased Employability among Patients with Mental Illness and/or Chronic Pain: A Randomized Controlled Trial
Multidisciplinary Intervention and Acceptance and Commitment Therapy for Return-to-Work and Increased Employability among Patients with Mental Illness and/or Chronic Pain: A Randomized Controlled Trial Open
Background: People on long-term sick leave often have a long-lasting process back to work, where the individuals may be in multiple and recurrent states; i.e., receiving different social security benefits or working, and over time they may…
View article: The Precision HYpertenSIon Care (PHYSIC) study: a double-blind, randomized, repeated cross-over study
The Precision HYpertenSIon Care (PHYSIC) study: a double-blind, randomized, repeated cross-over study Open
High blood pressure is the leading risk factor for premature deaths and a major cost to societies worldwide. Effective blood pressure-lowering drugs are available, but patient adherence to them is low, likely partly due to side effects. To…
View article: Motivation for return to work and actual return to work among people on long-term sick leave due to pain syndrome or mental health conditions
Motivation for return to work and actual return to work among people on long-term sick leave due to pain syndrome or mental health conditions Open
Purpose: The purpose of this study was to investigate associations between motivation for return to work and actual return to work, or increased employability among people on long-term sick leave.Materials and methods: Data by responses to…
View article: 2.11-P3Comprehensive health literacy is associated with experiences of the health examination for asylum seekers - A Swedish cross-sectional study
2.11-P3Comprehensive health literacy is associated with experiences of the health examination for asylum seekers - A Swedish cross-sectional study Open
Comprehensive health literacy is associated with experiences of the health examination for asylum seekers - A Swedish cross-sectional study
View article: Poor health and refraining from seeking healthcare are associated with comprehensive health literacy among refugees: a Swedish cross-sectional study
Poor health and refraining from seeking healthcare are associated with comprehensive health literacy among refugees: a Swedish cross-sectional study Open
A considerable proportion of the refugees in Sweden have limited CHL, and report less than good health and impaired well-being, or that they have refrained from seeking healthcare. Furthermore, CHL is associated with the above-mentioned fa…
View article: Creating falseness—How to establish statistical evidence of the untrue
Creating falseness—How to establish statistical evidence of the untrue Open
Null hypothesis significance testing is the typical statistical approach in search of the truthfulness of hypotheses. This method does not formally consider the prior credence in the hypothesis, which affects the chances of reaching correc…
View article: Housing Type and Neighbourhood Safety Behaviour Predicts Self-rated Health, Psychological Well-being and Frequency of Recent Unhealthy Days: A Comparative Cross-sectional Study of the General Population in Sweden
Housing Type and Neighbourhood Safety Behaviour Predicts Self-rated Health, Psychological Well-being and Frequency of Recent Unhealthy Days: A Comparative Cross-sectional Study of the General Population in Sweden Open
This study aimed at analysing associations among housing type, neighbourhood safety behaviour, self-rated health (SRH), psychological well-being and unhealthy days in the general population. From 2004 to 2013, 90, 845 Swedes completed a qu…
View article: Time-based measures of treatment effect: reassessment of ticagrelor and clopidogrel from the PLATO trial
Time-based measures of treatment effect: reassessment of ticagrelor and clopidogrel from the PLATO trial Open
Objective Treatment effects to binary endpoints using time-to-event data in randomised controlled trials are typically summarised by reporting HRs derived with Cox proportional hazard models. Alternative and complementary methods include s…