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View article: Creating an Improved Diatoxanthin Production Line by Knocking Out CpSRP54 in the zep3 Background in the Marine Diatom Phaeodactylum tricornutum
Creating an Improved Diatoxanthin Production Line by Knocking Out CpSRP54 in the zep3 Background in the Marine Diatom Phaeodactylum tricornutum Open
Diatoxanthin is a photoprotective carotenoid found in a few groups of microalgae displaying in vitro anti-inflammatory and anti-cancer properties, making it a promising candidate for nutraceutical, pharmaceutical, and cosmetic applications…
View article: Sensing Light Underwater
Sensing Light Underwater Open
Diatoms are a group of unicellular eukaryotic microalgae of high evolutionary success and of ecological importance. Like all photosynthetic organisms, they need to tightly regulate their photosynthetic machinery to both generate enough ene…
View article: <i>Skeletonema marinoi</i> ecotypes show specific habitat‐related responses to fluctuating light supporting high potential for growth under photobioreactor light regime
<i>Skeletonema marinoi</i> ecotypes show specific habitat‐related responses to fluctuating light supporting high potential for growth under photobioreactor light regime Open
Summary Diatoms are a diverse group of phytoplankton usually dominating areas characterized by rapidly shifting light conditions. Because of their high growth rates and interesting biochemical profile, their biomass is considered for vario…
View article: Zeaxanthin epoxidase 3 Knockout Mutants of the Model Diatom Phaeodactylum tricornutum Enable Commercial Production of the Bioactive Carotenoid Diatoxanthin
Zeaxanthin epoxidase 3 Knockout Mutants of the Model Diatom Phaeodactylum tricornutum Enable Commercial Production of the Bioactive Carotenoid Diatoxanthin Open
Carotenoids are pigments that have a range of functions in human health. The carotenoid diatoxanthin is suggested to have antioxidant, anti-inflammatory and chemo-preventive properties. Diatoxanthin is only produced by a few groups of micr…
View article: <em>Zeaxanthin Epoxidase</em> 3 Knockout Mutants of the Model Diatom <em>Phaeodactylum tricornutum</em> Enable Commercial Production of the Bioactive Carotenoid Diatoxanthin
<em>Zeaxanthin Epoxidase</em> 3 Knockout Mutants of the Model Diatom <em>Phaeodactylum tricornutum</em> Enable Commercial Production of the Bioactive Carotenoid Diatoxanthin Open
Antioxidant, anti-inflammatory and chemo-preventive features have been reported for the carotenoid diatoxanthin. Diatoxanthin is only produced by a few groups of microalgae where it functions in photoprotection. Its large-scale production …
View article: Loss of CpFTSY Reduces Photosynthetic Performance and Affects Insertion of PsaC of PSI in Diatoms
Loss of CpFTSY Reduces Photosynthetic Performance and Affects Insertion of PsaC of PSI in Diatoms Open
The chloroplast signal recognition particle (CpSRP) receptor (CpFTSY) is a component of the CpSRP pathway that post-translationally targets light-harvesting complex proteins (LHCPs) to the thylakoid membranes in plants and green algae cont…
View article: PAMP-Induced secreted Peptide-Like 6 (PIPL6) functions as an amplifier of plant immune response through RLK7 and WRKY33 module
PAMP-Induced secreted Peptide-Like 6 (PIPL6) functions as an amplifier of plant immune response through RLK7 and WRKY33 module Open
Plant peptide hormones are engaged in the regulation of plant developmental programs and immunity. PAMP-Induced Peptide (PIP) hormones are new class of signaling peptide with diverse functional roles in the regulation of plant development …
View article: IIb‐RAD‐sequencing coupled with random forest classification indicates regional population structuring and sex‐specific differentiation in salmon lice (<i>Lepeophtheirus salmonis</i>)
IIb‐RAD‐sequencing coupled with random forest classification indicates regional population structuring and sex‐specific differentiation in salmon lice (<i>Lepeophtheirus salmonis</i>) Open
The aquaculture industry has been dealing with salmon lice problems forming serious threats to salmonid farming. Several treatment approaches have been used to control the parasite. Treatment effectiveness must be optimized, and the system…
View article: Commensal and Opportunistic Bacteria Present in the Microbiota in Atlantic Cod (Gadus morhua) Larvae Differentially Alter the Hosts’ Innate Immune Responses
Commensal and Opportunistic Bacteria Present in the Microbiota in Atlantic Cod (Gadus morhua) Larvae Differentially Alter the Hosts’ Innate Immune Responses Open
The roles of host-associated bacteria have gained attention lately, and we now recognise that the microbiota is essential in processes such as digestion, development of the immune system and gut function. In this study, Atlantic cod larvae…
View article: Principles and Methods of Counteracting Harmful Salmon–Arthropod Interactions in Salmon Farming: Addressing Possibilities, Limitations, and Future Options
Principles and Methods of Counteracting Harmful Salmon–Arthropod Interactions in Salmon Farming: Addressing Possibilities, Limitations, and Future Options Open
The arthropod salmon louse ( Lepeophtheirus salmonis ) is a major threat to Atlantic salmon aquaculture and wild salmonids. Essentially like in monoculture, very high concentrations of susceptible hosts may result in high reproduction and …
View article: Simultaneous knockout of multiple <i>LHCF</i> genes using single sgRNAs and engineering of a high‐fidelity Cas9 for precise genome editing in marine algae
Simultaneous knockout of multiple <i>LHCF</i> genes using single sgRNAs and engineering of a high‐fidelity Cas9 for precise genome editing in marine algae Open
Summary The CRISPR/Cas9 system is an RNA‐guided sequence‐specific genome editing tool, which has been adopted for single or multiple gene editing in a wide range of organisms. When working with gene families with functional redundancy, kno…
View article: Functional studies of CpSRP54 in diatoms show that the mechanism of thylakoid protein insertion differs from that in plants and green algae
Functional studies of CpSRP54 in diatoms show that the mechanism of thylakoid protein insertion differs from that in plants and green algae Open
SUMMARY The chloroplast signal recognition particle 54 kDa (CpSRP54) protein is a member of the CpSRP pathway known to target proteins to thylakoid membranes in plants and green algae. Loss of CpSRP54 in the marine diatom Phaeodactylum tri…
View article: Phenylalanine Hydroxylase RNAi Knockdown Negatively Affects Larval Development, Molting and Swimming Performance of Salmon Lice
Phenylalanine Hydroxylase RNAi Knockdown Negatively Affects Larval Development, Molting and Swimming Performance of Salmon Lice Open
Phenylalanine hydroxylase (PAH) is a crucial enzyme involved in tyrosine biosynthesis, having roles in neurological and physiological processes. The purpose of PAH has received little attention in crustaceans despite extensive investigatio…
View article: Author Correction: The Seminavis robusta genome provides insights into the evolutionary adaptations of benthic diatoms
Author Correction: The Seminavis robusta genome provides insights into the evolutionary adaptations of benthic diatoms Open
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
View article: Light Regulation of LHCX Genes in the Benthic Diatom Seminavis robusta
Light Regulation of LHCX Genes in the Benthic Diatom Seminavis robusta Open
Intertidal benthic diatoms experience a highly variable light regime, which especially challenges these organisms to cope with excess light energy during low tide. Non-photochemical quenching of chlorophyll fluorescence (NPQ) is one of the…
View article: Targeted mutagenesis of Δ5 and Δ6 fatty acyl desaturases induce multiplex-mutagenesis and lipogenesis in Atlantic salmon (<i>Salmo salar</i>)
Targeted mutagenesis of Δ5 and Δ6 fatty acyl desaturases induce multiplex-mutagenesis and lipogenesis in Atlantic salmon (<i>Salmo salar</i>) Open
With declining wild fish populations, farmed Atlantic salmon ( Salmo salar ) has gained popularity as a source for healthy long-chain highly unsaturated fatty acids (LC-HUFA) including 20:5n-3 and 22:6n-3. However, the introduction of plan…
View article: The Role of a Glucosinolate-Derived Nitrile in Plant Immune Responses
The Role of a Glucosinolate-Derived Nitrile in Plant Immune Responses Open
Glucosinolates are defense-related secondary metabolites found in Brassicaceae. When Brassicaceae come under attack, glucosinolates are hydrolyzed into different forms of glucosinolate hydrolysis products (GHPs). Among the GHPs, isothiocya…
View article: The<i>Seminavis robusta</i>genome provides insights into the evolutionary adaptations of benthic diatoms
The<i>Seminavis robusta</i>genome provides insights into the evolutionary adaptations of benthic diatoms Open
Benthic diatoms are the main primary producers in shallow freshwater and coastal environments, fulfilling important ecological functions such as nutrient cycling and sediment stabilization. However, little is known about their evolutionary…
View article: Additional file 3 of Targeted mutagenesis of ∆5 and ∆6 fatty acyl desaturases induce dysregulation of lipid metabolism in Atlantic salmon (Salmo salar)
Additional file 3 of Targeted mutagenesis of ∆5 and ∆6 fatty acyl desaturases induce dysregulation of lipid metabolism in Atlantic salmon (Salmo salar) Open
(CSV 3 kb)
View article: Additional file 1 of Targeted mutagenesis of ∆5 and ∆6 fatty acyl desaturases induce dysregulation of lipid metabolism in Atlantic salmon (Salmo salar)
Additional file 1 of Targeted mutagenesis of ∆5 and ∆6 fatty acyl desaturases induce dysregulation of lipid metabolism in Atlantic salmon (Salmo salar) Open
(XLSX 608 kb)
View article: Additional file 2 of Targeted mutagenesis of ∆5 and ∆6 fatty acyl desaturases induce dysregulation of lipid metabolism in Atlantic salmon (Salmo salar)
Additional file 2 of Targeted mutagenesis of ∆5 and ∆6 fatty acyl desaturases induce dysregulation of lipid metabolism in Atlantic salmon (Salmo salar) Open
(CSV 61 kb)
View article: PAMP-INDUCED SECRETED PEPTIDE 3 (PIP3) modulates immunity in Arabidopsis thaliana
PAMP-INDUCED SECRETED PEPTIDE 3 (PIP3) modulates immunity in Arabidopsis thaliana Open
Small post-translationally modified peptides are important signalling components of plant defence responses against phytopathogens, acting both as positive and negative modulators. PAMP-INDUCED SECRETED PEPTIDE (PIP) 1 and 2 has been shown…
View article: The Myb‐like transcription factor phosphorus starvation response (PtPSR) controls conditional P acquisition and remodelling in marine microalgae
The Myb‐like transcription factor phosphorus starvation response (PtPSR) controls conditional P acquisition and remodelling in marine microalgae Open
Summary Phosphorus (P) is one of the limiting macronutrients for algal growth in marine environments. Microalgae have developed adaptation mechanisms to P limitation that involve remodelling of internal phosphate resources and accumulation…
View article: Loss of ALBINO3b Insertase Results in Truncated Light-Harvesting Antenna in Diatoms
Loss of ALBINO3b Insertase Results in Truncated Light-Harvesting Antenna in Diatoms Open
The family of chloroplast ALBINO3 (ALB3) proteins function in the insertion and assembly of thylakoid membrane protein complexes. Loss of ALB3b in the marine diatom Phaeodactylum tricornutum leads to a striking change of cell color from th…
View article: bHLH-PAS protein RITMO1 regulates diel biological rhythms in the marine diatom <i>Phaeodactylum tricornutum</i>
bHLH-PAS protein RITMO1 regulates diel biological rhythms in the marine diatom <i>Phaeodactylum tricornutum</i> Open
Periodic light–dark cycles govern the timing of basic biological processes in organisms inhabiting land as well as the sea, where life evolved. Although prominent marine phytoplanktonic organisms such as diatoms show robust diel rhythms, t…