Perumal Vanamail
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View article: Bridging Biology and Therapy: Advances in Management of Bipolar Disorder
Bridging Biology and Therapy: Advances in Management of Bipolar Disorder Open
Bipolar disorder is a complex psychiatric illness that is characterized by alternating episodes of mania and depression that significantly affect the quality of life. It is a chronic condition that has multifactorial pathophysiological mec…
View article: Statistical Glossaries and Biostatistical Aspects in Obstetrics and Gynecology
Statistical Glossaries and Biostatistical Aspects in Obstetrics and Gynecology Open
A BSTRACT This article emphasizes the transformative power of statistical glossaries and biostatistical methods in obstetrics and gynecology. These glossaries illuminate essential statistical terms and concepts, enriching our understanding…
View article: From Calculi to Infection: A Comprehensive Review of the Dual Burden of Kidney Stones and UTIs
From Calculi to Infection: A Comprehensive Review of the Dual Burden of Kidney Stones and UTIs Open
Infection in the urinary tract and stones in the kidney are common, frequently linked illnesses that have a big impact on public health. With an emphasis on the cyclical relationship between recurring infections and stone development, this…
View article: Syndromic Indicators and Wastewater Surveillance of SARS-CoV-2 – A Population-Based Longitudinal Study from South India
Syndromic Indicators and Wastewater Surveillance of SARS-CoV-2 – A Population-Based Longitudinal Study from South India Open
Background: The COVID-19 pandemic has highlighted the need for effective surveillance systems to monitor and predict disease outbreaks. This study aims to investigate the relationship between syndromic indicators and wastewater surveillanc…
View article: The serum levels of leptin and adiponectin in endometrial carcinoma and their association with histopathological factors
The serum levels of leptin and adiponectin in endometrial carcinoma and their association with histopathological factors Open
Introduction: Adipokines like leptin and adiponectin are hypothesized to play a role in the development of obesity-related cancers like endometrial cancers by influencing inflammation, angiogenesis, apoptosis, and tumorigenesis. We aimed t…
View article: Clinical, radiological and functional outcome following surgical fixation of acetabular fractures
Clinical, radiological and functional outcome following surgical fixation of acetabular fractures Open
: Acetabular fractures are commonly caused by high-velocity injuries that can result from falls from heights or motor vehicle accidents. Surgical fixation has been found to result in improved clinical outcomes such as reduced pain, improve…
View article: A Survey on Relation of Menopause to Metabolic Syndrome - SAFOMS STUDY (South Asian Federation of Menopause Societies) - Interim Analysis
A Survey on Relation of Menopause to Metabolic Syndrome - SAFOMS STUDY (South Asian Federation of Menopause Societies) - Interim Analysis Open
A BSTRACT Background: Metabolic syndrome (MS) is a spectrum of disorders that includes dysglycemia, dyslipidemia, central obesity, and hypertension. South Asian Indians are more prone to harbor MS at a younger age compared to Caucasians. H…
View article: Predictive and prognostic significance of placental growth factor in pregnant women at high-risk for development of preeclampsia
Predictive and prognostic significance of placental growth factor in pregnant women at high-risk for development of preeclampsia Open
Background: The study aimed to assess the predictive and prognostic role of placental growth factor (PlGF) in high-risk antenatal women for development of preeclampsia (PE). Methods: In this observational cohort study, antenatal women with…
View article: Prevalence of postpartum depression & anxiety among women in rural India: Risk factors & psychosocial correlates
Prevalence of postpartum depression & anxiety among women in rural India: Risk factors & psychosocial correlates Open
Background & objectives: Postpartum depression and anxiety (PPD/A) impact a woman’s physical and psychological wellbeing. In the absence of corroboratory evidence from the community setting in India, the present study was undertaken to exa…
View article: #670 Diagnostic performance of IOTA simple rules, IOTA adnex, girads and orads reporting system in evaluation of adnexal masses
#670 Diagnostic performance of IOTA simple rules, IOTA adnex, girads and orads reporting system in evaluation of adnexal masses Open
Introduction/Background Ultrasound is the most commonly used imaging modality for pre-operative discrimination of adnexal masses owing to its wider availability and ease of use. USG interpretation is observer dependent and is limited by it…
View article: A prospective randomized controlled trial to study the effect of prenatal yoga on maternal weight gain and psychological stress in pregnancy and its association with pregnancy outcomes
A prospective randomized controlled trial to study the effect of prenatal yoga on maternal weight gain and psychological stress in pregnancy and its association with pregnancy outcomes Open
Background: Objective of study was to evaluate the effect of prenatal yoga on maternal gestational weight gain (GWG) and psychological stress in pregnancy (PSS) and to evaluate the effect of prenatal yoga on labour outcomes. Methods: Prosp…
View article: A joinpoint regression model to determine COVID-19 virulence due to vaccination programme in India: a longitudinal analysis from 2020 to 2022
A joinpoint regression model to determine COVID-19 virulence due to vaccination programme in India: a longitudinal analysis from 2020 to 2022 Open
Background In late 2019, coronavirus disease, an acute respiratory illness caused by the novel coronavirus (SARS-CoV-2), was designated COVID-19 and declared a pandemic. The interim guidance for prevention is through voluntary quarantine, …
View article: Prediction of pre-eclampsia in diabetic pregnant women
Prediction of pre-eclampsia in diabetic pregnant women Open
Background & objectives: Gestational or preexisting diabetes is one of the risk factors of pre-eclampsia. Both are responsible for higher maternal and fetal complications. The objective was to study clinical risk factors of pre-eclampsia a…
View article: Stigma and stigma-induced stress in filarial lymphoedema patients in Puducherry, India
Stigma and stigma-induced stress in filarial lymphoedema patients in Puducherry, India Open
Introduction: The morbidity management and disability prevention (MMDP) strategy for elimination of lymphatic filariasis (ELF) focuses on alleviating the sufferings of about 36 million filariasis patients living in 49 endemic countries. At…
View article: SCOPE: Surveillance of COVID-19 in pregnancy- results of a multicentric ambispective case-control study on clinical presentation and maternal outcomes in India between April to November 2020
SCOPE: Surveillance of COVID-19 in pregnancy- results of a multicentric ambispective case-control study on clinical presentation and maternal outcomes in India between April to November 2020 Open
Objective To determine the clinical manifestations, risk factors, treatment modalities and maternal outcomes in pregnant women with lab-confirmed COVID-19 and compare it with COVID-19 negative pregnant women in same age group. Design Multi…
View article: EP119/#992 A case-control study of adipokines in endometrial cancer and correlation with prognostic factors
EP119/#992 A case-control study of adipokines in endometrial cancer and correlation with prognostic factors Open
Objectives Adipokines like leptin and adiponectin play an important role in inflammation, angiogenesis, apoptosis and tumourigenesis. Such adipokines are postulated to play a role in development of obesity related cancers like endometrial …
View article: Evaluation of the cell-free DNA integrity index as a liquid biopsy marker to differentiate hepatocellular carcinoma from chronic liver disease
Evaluation of the cell-free DNA integrity index as a liquid biopsy marker to differentiate hepatocellular carcinoma from chronic liver disease Open
Background: Hepatocellular carcinoma (HCC) occurs in the majority of patients with underlying chronic liver disease (CLD) of viral and non-viral etiologies, which requires screening for early HCC diagnosis. Liquid biopsy holds great promis…
View article: Pattern recognition receptor CD14 gene polymorphisms in alcohol use disorder patients and its Influence on liver disease susceptibility
Pattern recognition receptor CD14 gene polymorphisms in alcohol use disorder patients and its Influence on liver disease susceptibility Open
Background Alcohol use disorders (AUDs) leading to liver disease is major concern over other spectrum of disorder. Excessive alcohol consumption resulting in leaky gut syndrome is attributed to alcohol-induced liver injury through portal t…
View article: Impact of geographical and seasonal temperature on sperm parameters in Indian men who were partners in subfertile couples – A retrospective analysis
Impact of geographical and seasonal temperature on sperm parameters in Indian men who were partners in subfertile couples – A retrospective analysis Open
Objective: To evaluate the impact of seasonal and geographical temperature on sperm parameters in Indian men who were partners in subfertile couples. Methods: A retrospective review of the records of semen analysis from January 2009 to Dec…
View article: O-292 Comparison of effect of two different trigger regimens; single (hCG) versus dual (hCG + Leuprolide) on outcome of fresh IVF cycles: A randomized controlled trial
O-292 Comparison of effect of two different trigger regimens; single (hCG) versus dual (hCG + Leuprolide) on outcome of fresh IVF cycles: A randomized controlled trial Open
Study question Does adding gonadotropin-releasing hormone agonist (GnRHa) to hCG trigger increases the number of high-grade embryos in GnRH antagonist protocol in fresh non-donor IVF? Summary answer Final oocyte maturation triggered by dua…
View article: iTRAQ proteomics of sentinel lymph nodes for identification of extracellular matrix proteins to flag metastasis in early breast cancer
iTRAQ proteomics of sentinel lymph nodes for identification of extracellular matrix proteins to flag metastasis in early breast cancer Open
View article: The Impact of the COVID-19 Pandemic on the Psychological Well-being of Healthcare Workers in Obstetrics and Gynaecology: An Observational Study at an Apex Institute
The Impact of the COVID-19 Pandemic on the Psychological Well-being of Healthcare Workers in Obstetrics and Gynaecology: An Observational Study at an Apex Institute Open
Background and objective The coronavirus disease 2019 (COVID-19) pandemic has affected the health, social, and economic sectors all over the world. With a view to assessing the impact of COVID-19 on the mental health of healthcare workers …
View article: A Single-Arm Pilot Study of Multicomponent Psychoeducational Intervention for Postpartum Depression and Anxiety in a Rural Community
A Single-Arm Pilot Study of Multicomponent Psychoeducational Intervention for Postpartum Depression and Anxiety in a Rural Community Open
Background: The prevalence of postpartum depression (PPD) and anxiety (PPA) is rising in India and efforts at generating local evidence for psychological intervention are scanty. We conducted a single-arm pilot study in an Indian rural com…
View article: Association of inflammatory biomarker abnormalities with mortality in COVID-19: a meta-analysis
Association of inflammatory biomarker abnormalities with mortality in COVID-19: a meta-analysis Open
View article: Psychological impact of suspension/postponement of fertility treatments on infertile women waiting during COVID pandemic
Psychological impact of suspension/postponement of fertility treatments on infertile women waiting during COVID pandemic Open
Objective To assess the psychological impact of suspension/postponement of various fertility treatments on infertile women during the coronavirus disease 2019 (COVID-19) pandemic.Methods This was a cross-sectional study conducted as an onl…
View article: Epidemiological Aspects of COVID-19 Disease in India during Nationwide Lockdown Phase- An Empirical Data-Based Analysis and its Implications on Interrupting the Transmission
Epidemiological Aspects of COVID-19 Disease in India during Nationwide Lockdown Phase- An Empirical Data-Based Analysis and its Implications on Interrupting the Transmission Open
Background: Covid-19 disease is pandemic in more than 85% of the countries in the world, with about 10 million cases and 0.5 million deaths as on July 2, 2020. In India reporting of the first case was on January 30, 2020, and to prevent ra…
View article: Effect of body temperature on the cyclic fatigue resistance of the nickel”titanium endodontic instruments: A systematic review and meta-analysis of in vitro studies
Effect of body temperature on the cyclic fatigue resistance of the nickel”titanium endodontic instruments: A systematic review and meta-analysis of in vitro studies Open
Within the limitation of the study, the cyclic fatigue resistance of heat-treated NiTi endodontic files is significantly reduced at body temperature when compared to room temperature. Cyclic fatigue testing should be conducted at simulated…
View article: Performance of Fetal Medicine Foundation algorithm for first trimester preeclampsia screening in an indigenous south Asian population
Performance of Fetal Medicine Foundation algorithm for first trimester preeclampsia screening in an indigenous south Asian population Open
View article: Autologous platelet-rich plasma optimizes endometrial thickness and pregnancy outcomes in women with refractory thin endometrium of varied aetiology during fresh and frozen-thawed embryo transfer cycles
Autologous platelet-rich plasma optimizes endometrial thickness and pregnancy outcomes in women with refractory thin endometrium of varied aetiology during fresh and frozen-thawed embryo transfer cycles Open
PRP enhances EMT significantly during fresh and FET cycles in thin endometrium associated with TB, PCOS and DOR, thus improving the CPR and LBR in these low prognosis patients.
View article: Diagnostic measures comparison for ovarian malignancy risk in Epithelial ovarian cancer patients: a meta-analysis
Diagnostic measures comparison for ovarian malignancy risk in Epithelial ovarian cancer patients: a meta-analysis Open