Pervinder Bhogal
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View article: Bridging Thrombolysis Does Not Achieve Better Outcomes Compared to Direct Mechanical Thrombectomy in Stroke Due to Internal Carotid Artery Occlusion
Bridging Thrombolysis Does Not Achieve Better Outcomes Compared to Direct Mechanical Thrombectomy in Stroke Due to Internal Carotid Artery Occlusion Open
Background and purpose. Mechanical thrombectomy (MT) is an effective treatment for patients with acute ischaemic stroke secondary to internal carotid artery (ICA) occlusion. Intravenous thrombolysis (IVT) prior to MT is also commonly admin…
View article: Decision-Making for Endovascular Thrombectomy in Patients With Large Vessel Occlusions and Mild Neurological Deficit: A Consensus Statement
Decision-Making for Endovascular Thrombectomy in Patients With Large Vessel Occlusions and Mild Neurological Deficit: A Consensus Statement Open
Acute ischemic stroke patients with mild deficits (National Institutes of Health Stroke Scale [NIHSS] of 0–5) but confirmed large vessel occlusions (LVO) present a clinical challenge for endovascular thrombectomy (EVT) decisions due to lim…
View article: Literature review and DELPHI consensus on follow-up and retreatment of intracranial aneurysms with intrasaccular devices
Literature review and DELPHI consensus on follow-up and retreatment of intracranial aneurysms with intrasaccular devices Open
Background Intracranial aneurysms are increasingly detected incidentally due to broader use of neuroimaging. Intrasaccular devices are frequently used to prevent rupture, yet standardized follow-up and retreatment strategies remain undefin…
View article: Health Economic Impact of Incomplete Reperfusion Patterns After Endovascular Thrombectomy in Acute Ischemic Stroke
Health Economic Impact of Incomplete Reperfusion Patterns After Endovascular Thrombectomy in Acute Ischemic Stroke Open
Background and Purpose Incomplete reperfusion in endovascular thrombectomy (EVT) impacts patients’ outcomes. Different incomplete reperfusion patterns may benefit from targeted therapeutic strategies, e.g. EVT-accessible incomplete reperfu…
View article: Extracranial–intracranial bypass for symptomatic intracranial arterial occlusion: a meta-analysis of individual patient data
Extracranial–intracranial bypass for symptomatic intracranial arterial occlusion: a meta-analysis of individual patient data Open
Patients with symptomatic atherosclerotic internal carotid artery (ICA) or middle cerebral artery (MCA) occlusions face a high risk of recurrent ischaemic stroke despite best medical therapy. Previous trials of extracranial–intracranial (E…
View article: The NeVa Net stent-retriever – initial report of 20 cases from two high volume centres
The NeVa Net stent-retriever – initial report of 20 cases from two high volume centres Open
Background Various different technologies have been developed to optimise the mechanical thrombectomy procedure and first pass recanalisation. We report our initial experience with the NeVa NET – a novel stent-retriever with built in dista…
View article: The NeVa stent-retriever – a single-centre real-world experience
The NeVa stent-retriever – a single-centre real-world experience Open
Stent-retriever-based mechanical thrombectomy (MT) is an effective treatment for acute ischemic stroke (AIS) caused by large vessel occlusion (LVO). First-pass effect (FPE) is one most powerful predictors of positive outcomes in LVO AIS pa…
View article: The initial experience with the Walrus balloon guide catheter – Results from two high-volume thrombectomy centres
The initial experience with the Walrus balloon guide catheter – Results from two high-volume thrombectomy centres Open
Background We report our initial experience on the use of the Walrus, a new generation balloon guide catheter (BGC) capable of accommodating large bore aspiration catheters for patients undergoing endovascular stroke thrombectomy for large…
View article: Intra-arterial lidocaine administration of lidocaine in middle meningeal artery for short-term treatment of subarachnoid hemorrhage-related headaches
Intra-arterial lidocaine administration of lidocaine in middle meningeal artery for short-term treatment of subarachnoid hemorrhage-related headaches Open
Background and purpose We report short- and intermediate-term effects on headaches with intra-arterial injection of lidocaine in the middle meningeal artery in patients with severe headaches associated with subarachnoid hemorrhage. Methods…
View article: Impact of number of passes and futile reperfusion in basilar artery occlusion acute ischaemic stroke
Impact of number of passes and futile reperfusion in basilar artery occlusion acute ischaemic stroke Open
Introduction: Mechanical thrombectomy (MT) is the standard of care in anterior circulation large vessel occlusion. A vital modifiable factor is successful reperfusion. While multiple passes improve the rates of successful reperfusion, prev…
View article: Effect of Proximal Blood Flow Arrest During Endovascular Thrombectomy (ProFATE): A Multicenter, Blinded-End Point, Randomized Clinical Trial
Effect of Proximal Blood Flow Arrest During Endovascular Thrombectomy (ProFATE): A Multicenter, Blinded-End Point, Randomized Clinical Trial Open
BACKGROUND: The effect of temporary blood flow arrest during endovascular thrombectomy for acute ischemic stroke is uncertain due to the lack of evidence from randomized controlled trials. We aimed to investigate whether temporary blood fl…
View article: Abstract 026: Initial Experience with the Walrus BGC results from 300 cases
Abstract 026: Initial Experience with the Walrus BGC results from 300 cases Open
Background Until recently only the Flowgate2 (Stryker Neurovascular) was available clinically despite multiple advances in aspiration catheter and stent‐retriever technology. The Walrus BGC (Q'Apel Medical Inc, Fremont, California, USA) is…
View article: Endovascular thrombectomy vs best medical management for late presentation acute ischaemic stroke with large vessel occlusion without CT perfusion or MR imaging selection: A systematic review and meta-analysis
Endovascular thrombectomy vs best medical management for late presentation acute ischaemic stroke with large vessel occlusion without CT perfusion or MR imaging selection: A systematic review and meta-analysis Open
Compared to BMM, late presenting stroke patients selected for EVT eligibility with NCCT/CTA only and treated with EVT achieved significantly higher rates of functional independence at 90 days, without increasing the incidence of sICH or mo…
View article: Treatment for middle cerebral artery bifurcation aneurysms: in silico comparison of the novel Contour device and conventional flow-diverters
Treatment for middle cerebral artery bifurcation aneurysms: in silico comparison of the novel Contour device and conventional flow-diverters Open
Endovascular treatment has become the standard therapy for cerebral aneurysms, while the effective treatment for middle cerebral artery (MCA) bifurcation aneurysms remains a challenge. Current flow-diverting techniques with endovascular co…
View article: Transauricular nerve stimulation in acute ischaemic stroke requiring mechanical thrombectomy: Protocol for a phase 2A, proof-of-concept, sham-controlled randomised trial
Transauricular nerve stimulation in acute ischaemic stroke requiring mechanical thrombectomy: Protocol for a phase 2A, proof-of-concept, sham-controlled randomised trial Open
Background Labile blood pressure after acute ischaemic stroke requiring mechanical thrombectomy is independently associated with poor patient outcomes. Objectives This study protocol describes is designed to determine whether transauricula…
View article: Refractory migraine: a cerebrovascular disease?
Refractory migraine: a cerebrovascular disease? Open
View article: The Stream Device—A Retrospective Review of 51 Cases
The Stream Device—A Retrospective Review of 51 Cases Open
Mechanical thrombectomy is the gold-standard treatment for patients that have suffered large-vessel occlusion (LVO) stroke. Various different stent-retrievers, aspiration catheters, and techniques have been developed to perform this proced…
View article: Antiplatelet therapy in aneurysmal subarachnoid hemorrhage: an updated meta-analysis
Antiplatelet therapy in aneurysmal subarachnoid hemorrhage: an updated meta-analysis Open
Antiplatelet therapy (AT) may serve to reduce the effects of aneurysmal subarachnoid hemorrhage (aSAH)-induced pro-coagulant state in the cerebral circulation. Several studies, however, have delivered conflicting conclusions on the efficac…
View article: P146/118 NeVa ONE registry interim analysis: recanalization outcomes from a large, real-world patient cohort
P146/118 NeVa ONE registry interim analysis: recanalization outcomes from a large, real-world patient cohort Open
Introduction The NeVa stent retriever has proven it's safety and performance for treating large vessel occlusion (LVO) in acute ischemic stroke (AIS) across multiple clinical studies including the most recently published CLEAR Trial. This …
View article: P154/193 Impact of stent-retriever tip design on distal embolization during mechanical thrombectomy: a randomized in vitro evaluation
P154/193 Impact of stent-retriever tip design on distal embolization during mechanical thrombectomy: a randomized in vitro evaluation Open
Introduction Repeated number of passes, clot fragmentation, and distal embolization during mechanical thrombectomy lead to worse clinical outcomes in acute ischemic stroke. Aim of Study This study aims to assess the recanalization and embo…
View article: Mechanical thrombectomy in medium vessel occlusions using the novel aspiration Q catheters: an international multicenter experience
Mechanical thrombectomy in medium vessel occlusions using the novel aspiration Q catheters: an international multicenter experience Open
Background Medium vessel occlusions (MeVOs) comprise a large proportion of all stroke events. We performed a multicenter study of MIVI Q catheters, a novel design that optimizes suction forces without an increase in lumen diameter, for the…
View article: O-013 Impact of stent-retriever tip design on distal embolization during mechanical thrombectomy – a randomized<i>in vitro</i>evaluation
O-013 Impact of stent-retriever tip design on distal embolization during mechanical thrombectomy – a randomized<i>in vitro</i>evaluation Open
Background Repeated number of passes, clot fragmentation, and distal embolization during mechanical thrombectomy lead to worse clinical outcomes in acute ischemic stroke. Objective To assess the recanalization and embolic outcomes of diffe…
View article: Direct dotterising or angioplasty of acute stroke due to tandem atherosclerotic occlusions
Direct dotterising or angioplasty of acute stroke due to tandem atherosclerotic occlusions Open
Background Tandem occlusions cause 10–15% of LVO acute ischemic strokes but are difficult to treat endovascularly and frequently excluded from clinical trials. The optimum endovascular method is still debated, however going directly throug…
View article: Comparison Between In‐Hospital and Community‐Onset Stroke Treated With Endovascular Thrombectomy: A Propensity Score–Matched Cohort Study
Comparison Between In‐Hospital and Community‐Onset Stroke Treated With Endovascular Thrombectomy: A Propensity Score–Matched Cohort Study Open
Background Patients with acute ischemic stroke onset during hospital admission often have concurrent illnesses, increased underlying comorbidities and are often associated with a delayed recognition of stroke onset, compared with patients …
View article: Effect of proximal blood flow arrest during endovascular thrombectomy (ProFATE): Study protocol for a multicentre randomised controlled trial
Effect of proximal blood flow arrest during endovascular thrombectomy (ProFATE): Study protocol for a multicentre randomised controlled trial Open
Background: Observational studies have demonstrated improved outcomes with the adjunctive use of balloon guide catheters (BGC) during endovascular thrombectomy (EVT) for anterior circulation acute ischaemic stroke (AIS). However, the lack …
View article: Incidence and predictors of poor functional outcome despite complete recanalisation following endovascular thrombectomy for acute ischaemic stroke
Incidence and predictors of poor functional outcome despite complete recanalisation following endovascular thrombectomy for acute ischaemic stroke Open
View article: Abstract Number ‐ 151: Impact of Stent‐Retriever Tip Design on Distal Embolization during Mechanical Thrombectomy
Abstract Number ‐ 151: Impact of Stent‐Retriever Tip Design on Distal Embolization during Mechanical Thrombectomy Open
Introduction Mechanical thrombectomy (MT) is a widely performed procedure for acute ischemic stroke (AIS) due to large vessel occlusion. Repeated number of passes, clot fragmentation, and distal embolization during MT lead to worse clinica…
View article: Thrombectomy for distal medium vessel occlusion stroke: Combined vs. single-device techniques - A systematic review and meta-analysis
Thrombectomy for distal medium vessel occlusion stroke: Combined vs. single-device techniques - A systematic review and meta-analysis Open
Background The optimal mechanical thrombectomy technique for acute ischaemic stroke (AIS) caused by distal, medium vessel occlusion (DMVO) is uncertain. We performed a systematic review and meta-analysis evaluating the efficacy and safety …
View article: Prehospital technologies for early stroke detection – A review
Prehospital technologies for early stroke detection – A review Open
The rate of neural circuitry loss in a typical large vessel occlusion well emphasizes that ‘Time is Brain’. Every untreated minute in a large vessel ischaemic stroke results in loss of 1.9 million neurons and 13.8 billion synapses. As such…
View article: Distal medium vessel occlusions in acute ischaemic stroke – Stent retriever versus direct aspiration: A systematic review and meta-analysis
Distal medium vessel occlusions in acute ischaemic stroke – Stent retriever versus direct aspiration: A systematic review and meta-analysis Open
Background Acute ischaemic stroke due to distal medium vessel occlusion (AIS-DMVO) causes significant morbidity. Endovascular thrombectomy advancement has made treating AIS-DMVO with stent retrievers (SR) and aspiration catheters (AC) poss…