Peta Burns
YOU?
Author Swipe
View article: Macrocyclic peptidomimetics as inhibitors of insulin-regulated aminopeptidase (IRAP)
Macrocyclic peptidomimetics as inhibitors of insulin-regulated aminopeptidase (IRAP) Open
The IRAP inhibition of the macrocyclic peptide, HA-08 has been explored by analogue design coupled to molecular dynamics analysis.
View article: Insulin‐regulated aminopeptidase inhibitor‐mediated increases in dendritic spine density are facilitated by glucose uptake
Insulin‐regulated aminopeptidase inhibitor‐mediated increases in dendritic spine density are facilitated by glucose uptake Open
Ethyl2‐acetylamino‐7‐hydroxy‐4‐pyridin‐3‐yl‐4H‐chromene‐3‐carboxylate (HFI‐419), the benzopyran‐based inhibitor of insulin‐regulated aminopeptidase (IRAP), has previously been shown to improve spatial working and recognition memory in rode…
View article: Insulin-regulated aminopeptidase inhibitors do not alter glucose handling in normal and diabetic rats
Insulin-regulated aminopeptidase inhibitors do not alter glucose handling in normal and diabetic rats Open
Insulin-regulated aminopeptidase (IRAP) co-localizes with the glucose transporter 4 (GLUT4) in GLUT4 storage vesicles (GSV) in insulin-responsive cells. In response to insulin, IRAP is the only transmembrane enzyme known to translocate tog…