Peter A. Brady
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View article: Leadless Versus Transvenous Single‐Chamber Ventricular Pacemakers: Real‐World Evidence From Aveir VR Coverage With Evidence Development Study
Leadless Versus Transvenous Single‐Chamber Ventricular Pacemakers: Real‐World Evidence From Aveir VR Coverage With Evidence Development Study Open
Background Aveir VR, a helix‐fixation leadless pacemaker (LP), was US Food and Drug Administration (FDA)‐approved in 2022. The performance of this novel LP has not been evaluated against transvenous single chamber ventricular pacemakers (T…
View article: Late Gadolinium Enhancement and Electrocardiographic Associations in Hypertrophic Cardiomyopathy
Late Gadolinium Enhancement and Electrocardiographic Associations in Hypertrophic Cardiomyopathy Open
Background Late gadolinium enhancement (LGE) on cardiovascular magnetic resonance (CMR) imaging is a well‐established indicator of myocardial fibrosis in hypertrophic cardiomyopathy (HCM). However, its association with electrocardiographic…
View article: The Utility and Validation of SCAI-CSWG Stages in Patients With Acute Myocardial Infarction-Related Cardiogenic Shock
The Utility and Validation of SCAI-CSWG Stages in Patients With Acute Myocardial Infarction-Related Cardiogenic Shock Open
This is the first study to validate SCAI-Cardiogenic Shock Working Group stages in a large cohort of patients with AMICS. The SCAI shock staging classification was significantly associated with higher short- and long-term mortality in this…
View article: Transcatheter aortic valve replacement in patients with chronic kidney disease: a multi-centre retrospective study
Transcatheter aortic valve replacement in patients with chronic kidney disease: a multi-centre retrospective study Open
Background: Chronic kidney disease (CKD) is a common comorbid condition in patients undergoing transcatheter aortic valve replacement (TAVR). Reported outcome studies on the association of baseline CKD and mortality is currently limited. O…
View article: Arrhythmogenic right ventricular cardiomyopathy mimicking Brugada – a case report
Arrhythmogenic right ventricular cardiomyopathy mimicking Brugada – a case report Open
We report a rare case of arrhythmogenic right ventricular cardiomyopathy (ARVC). Middle-aged Kuwaiti gentleman presented to a polyclinic with complaints of dizziness and palpitation. Electrocardiogram (ECG) at the polyclinic showed polymor…
View article: Associations between clinical and social factors and anticoagulant prescription among patients with atrial fibrillation: A retrospective cohort study from a large healthcare system
Associations between clinical and social factors and anticoagulant prescription among patients with atrial fibrillation: A retrospective cohort study from a large healthcare system Open
Background Patient clinical factors and social determinants of health (SDOH) are associated with an increased risk of stroke for patients with atrial fibrillation (AF); however, the association between these factors and the management of A…
View article: In Hospital Mortality in Acute Heart Failure with Idiopathic Cardiomyopathy and Type II Diabetes
In Hospital Mortality in Acute Heart Failure with Idiopathic Cardiomyopathy and Type II Diabetes Open
Background: Clinical characteristics and outcomes in patients with type 2 diabetes mellitus (T2DM) and acute heart failure (AHF) patients with idiopathic cardiomyopathy are not well known. Objective: The objective of our study is to determ…
View article: Predictors of Early and Late Mortality after Transcatheter Aortic Valve Implantation: A Multicenter Retrospective Chinese Study
Predictors of Early and Late Mortality after Transcatheter Aortic Valve Implantation: A Multicenter Retrospective Chinese Study Open
Background: Patients undergoing TAVR constitute a high-risk population given their comorbidities and out-of-hospital mortality rates remain high despite significant improvements in the overall procedural outcomes. Objectives: The objective…
View article: Development and Validation of R-hf Risk Score in Acute Heart Failure Patients in the Middle East
Development and Validation of R-hf Risk Score in Acute Heart Failure Patients in the Middle East Open
Objectives: The Rajan’s heart failure (R-hf) score was proposed to aid risk stratification in heart failure patients. The aim of this study was to validate R-hf risk score in patients with acute decompensated heart failure. Methods: R-hf r…
View article: Neutrophil to lymphocyte ratio and in-hospital mortality among patients with SARS-CoV-2: A retrospective study
Neutrophil to lymphocyte ratio and in-hospital mortality among patients with SARS-CoV-2: A retrospective study Open
The goal of this study was to investigate in-hospital mortality in patients suffering from acute respiratory syndrome coronavirus 2 (SARS-CoV-2) relative to the neutrophil to lymphocyte ratio (NLR) and to determine if there are gender disp…
View article: Impact of social determinants of health on anticoagulant use among patients with atrial fibrillation: Systemic review and meta-analysis
Impact of social determinants of health on anticoagulant use among patients with atrial fibrillation: Systemic review and meta-analysis Open
Background: A growing body of literature now exists examining associations between social determinants of health (SDOH) and adverse outcomes in patients with atrial fibrillation; however, little is available on anticoagulant prescriptions …
View article: Risk of Sudden Death in a General Unbiased Epidemiological Cohort of Sarcoidosis
Risk of Sudden Death in a General Unbiased Epidemiological Cohort of Sarcoidosis Open
Background Sarcoidosis is an inflammatory, noncaseating, granulomatous disorder of unknown cause that can affect any body system and is associated with cardiovascular disease including sudden cardiac death (SCD). Cardiac involvement in sar…
View article: Validation of R-hf risk score for risk stratification in ischemic heart failure patients: A prospective cohort study
Validation of R-hf risk score for risk stratification in ischemic heart failure patients: A prospective cohort study Open
Lower R-hf risk score is a significant predictor of mortality in ischemic and non-ischemic heart failure patients. Risk score can be accessed at https://www.hfriskcalc.in.
View article: Prognostic Value of Integral Assessment of Congestion in Patients Hospitalized with Acute Decompensated Chronic Heart Failure
Prognostic Value of Integral Assessment of Congestion in Patients Hospitalized with Acute Decompensated Chronic Heart Failure Open
Background: Systemic congestion is the leading pathophysiological mechanism of decompensated heart failure (HF), and hospitalization and poor prognosis. Unfortunately, patients are discharged with residual congestion, possibly due to the l…
View article: In-hospital mortality in SARS-CoV-2 stratified by sex diffrences: A retrospective cross-sectional cohort study
In-hospital mortality in SARS-CoV-2 stratified by sex diffrences: A retrospective cross-sectional cohort study Open
Male gender was an independent predictor of in-hospital mortality in this study. The mortality rate among male SARS-CoV-2 patients was 2.8 times higher when compared with females.
View article: Clinical Outcome and Risk Assessment in Hospitalized COVID-19 Patients with Elevated Transaminases and Acute Kidney Injury: A Single Center Study
Clinical Outcome and Risk Assessment in Hospitalized COVID-19 Patients with Elevated Transaminases and Acute Kidney Injury: A Single Center Study Open
Objectives: Initial reports indicate a high incidence of abnormal aspartate aminotransferase (AST) and alanine aminotransferase (ALT) levels in patients with COVID-19 and possible association with acute kidney injury (AKI). We aimed to inv…
View article: Clinical outcomes of transcatheter aortic valve replacement stratified by left ventricular ejection fraction: A single centre pilot study
Clinical outcomes of transcatheter aortic valve replacement stratified by left ventricular ejection fraction: A single centre pilot study Open
Severe AS with EF <40% constitute a remarkable proportion of patients undergoing TAVR. Preliminary results of post-operative conduction disturbances and in hospital mortality in HFrEF patients were concluded to not differ from patients wit…
View article: In-hospital Mortality in SARS-CoV-2 stratified by Gender: A Retrospective Study
In-hospital Mortality in SARS-CoV-2 stratified by Gender: A Retrospective Study Open
Background: The aim of this study was to determine in-hospital mortality in patients presenting with acute respiratory syndrome corona virus 2 (SARS-CoV-2) and to evaluate for any differences in outcome according to gender. Methods: Patien…
View article: A single-center comparative study of lung ultrasound <em>versus</em> chest computed tomography during the COVID-19 era
A single-center comparative study of lung ultrasound <em>versus</em> chest computed tomography during the COVID-19 era Open
Background: Lung ultrasound (LUS) is a bedside imaging tool that has proven useful in identifying and assessing the severity of pulmonary pathology. The aim of this study was to determine LUS patterns, their clinical significance, and how …
View article: In‐hospital mortality in SARS‐CoV‐2 stratified by serum 25‐hydroxy‐vitamin D levels: A retrospective study
In‐hospital mortality in SARS‐CoV‐2 stratified by serum 25‐hydroxy‐vitamin D levels: A retrospective study Open
This study is done to estimаte in‐hоsрitаl mоrtаlity in раtients with severe асute resрirаtоry syndrоme соrоnаvirus 2 (SАRS‐СоV‐2) strаtified by Vitamin‐D (Vit‐D) levels. Раtients were strаtified ассоrding tо by serum 25‐hydroxy‐vitamin D …
View article: Cardiac Involvement in Facioscapulohumeral Muscular Dystrophy (FSHD)
Cardiac Involvement in Facioscapulohumeral Muscular Dystrophy (FSHD) Open
Background: Facioscapulohumeral muscular dystrophy (FSHD) is one of the most common muscular dystrophies and predominantly affects facial and shoulder girdle muscles. Previous case reports and cohort studies identified minor cardiac abnorm…
View article: Post Procedural Peak Left Atrial Contraction Strain Predicts Recurrence of Arrhythmia After Catheter Ablation of Atrial Fibrillation
Post Procedural Peak Left Atrial Contraction Strain Predicts Recurrence of Arrhythmia After Catheter Ablation of Atrial Fibrillation Open
Background: Left atrial (LA) function can be impaired by the atrial fibrillation (AF) ablation and might be associated with the risk of recurrence. We sought to determine whether the post-procedural changes in LA function impact the risk o…
View article: Prognostic utility of cardiopulmonary exercise testing indices in arrhythmogenic right ventricular cardiomyopathy
Prognostic utility of cardiopulmonary exercise testing indices in arrhythmogenic right ventricular cardiomyopathy Open
Introduction Cardiopulmonary exercise testing (CPET) has an established role in the clinical evaluation of exercise intolerance and in the risk stratification of patients with heart failure. There is limited data assessing its prognostic u…
View article: State of the Art Review on Genetics and Precision Medicine in Arrhythmogenic Cardiomyopathy
State of the Art Review on Genetics and Precision Medicine in Arrhythmogenic Cardiomyopathy Open
Arrhythmogenic cardiomyopathy (ACM) is an inherited cardiomyopathy characterised by ventricular arrhythmia and an increased risk of sudden cardiac death (SCD). Numerous genetic determinants and phenotypic manifestations have been discovere…