Peter C. Ferguson
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View article: Supplementary Table 5 from Optimal Factors That Influence the Establishment of Successful Primary Human Soft-Tissue Sarcoma Cell Lines
Supplementary Table 5 from Optimal Factors That Influence the Establishment of Successful Primary Human Soft-Tissue Sarcoma Cell Lines Open
Supplementary Table 5. The histology of the human primary specimens and corresponding xenograft specimens as reviewed by an expert pathologist.
View article: Data from Optimal Factors That Influence the Establishment of Successful Primary Human Soft-Tissue Sarcoma Cell Lines
Data from Optimal Factors That Influence the Establishment of Successful Primary Human Soft-Tissue Sarcoma Cell Lines Open
Purpose:The development of improved therapies is complicated by the limited availability of well-characterized human models, especially in rare tumors such as soft-tissue sarcoma (STS). We report the optimization of conditions and clinical…
View article: Supplementary Table 2 from Optimal Factors That Influence the Establishment of Successful Primary Human Soft-Tissue Sarcoma Cell Lines
Supplementary Table 2 from Optimal Factors That Influence the Establishment of Successful Primary Human Soft-Tissue Sarcoma Cell Lines Open
Supplementary Table 2. Characteristics of primary specimens used to initiate cell lines by type.
View article: Supplementary Table 3 from Optimal Factors That Influence the Establishment of Successful Primary Human Soft-Tissue Sarcoma Cell Lines
Supplementary Table 3 from Optimal Factors That Influence the Establishment of Successful Primary Human Soft-Tissue Sarcoma Cell Lines Open
Supplementary Table 3. Characteristics of persistently growing cell lines (n = 46).
View article: Supplementary Table 4 from Optimal Factors That Influence the Establishment of Successful Primary Human Soft-Tissue Sarcoma Cell Lines
Supplementary Table 4 from Optimal Factors That Influence the Establishment of Successful Primary Human Soft-Tissue Sarcoma Cell Lines Open
Supplementary Table 4. Short tandem repeat profiling of 40 cases with bulk specimens and cell line materials available for 10 loci.
View article: Supplementary Figure 1 from Optimal Factors That Influence the Establishment of Successful Primary Human Soft-Tissue Sarcoma Cell Lines
Supplementary Figure 1 from Optimal Factors That Influence the Establishment of Successful Primary Human Soft-Tissue Sarcoma Cell Lines Open
Supplementary Figure 1. A Kaplan-Meier overall survival (OS) curve based on STS type for 136 patients who gave primary specimens and had available follow up information
View article: Supplementary Figure 3 from Optimal Factors That Influence the Establishment of Successful Primary Human Soft-Tissue Sarcoma Cell Lines
Supplementary Figure 3 from Optimal Factors That Influence the Establishment of Successful Primary Human Soft-Tissue Sarcoma Cell Lines Open
Supplementary Figure 3. Comparison of successfully xenografted cell lines to primary tumors (H&E, x400). The top panel shows xenograft specimens and the lower panel corresponding patient-derived primary tumors. Each of xenografts shows a m…
View article: Supplementary Figure 2 from Optimal Factors That Influence the Establishment of Successful Primary Human Soft-Tissue Sarcoma Cell Lines
Supplementary Figure 2 from Optimal Factors That Influence the Establishment of Successful Primary Human Soft-Tissue Sarcoma Cell Lines Open
Supplementary Figure 2. Kaplan-Meier disease-free survival (DFS) curves for patients who gave primary specimens and did not present with recurrent disease by STS type for A) LMS (n = 55), B) MFS (n = 26), and C) UPS (n = 40) patients based…
View article: Supplementary Table 1 from Optimal Factors That Influence the Establishment of Successful Primary Human Soft-Tissue Sarcoma Cell Lines
Supplementary Table 1 from Optimal Factors That Influence the Establishment of Successful Primary Human Soft-Tissue Sarcoma Cell Lines Open
Supplementary Table 1. Characteristics of recurrent specimens used to initiate cell lines (n = 23).
View article: Preoperative intensity‐modulated radiation therapy in lower extremity soft tissue sarcomas with and without dose avoidance of uninvolved skin/subcutaneous tissue
Preoperative intensity‐modulated radiation therapy in lower extremity soft tissue sarcomas with and without dose avoidance of uninvolved skin/subcutaneous tissue Open
Background The objective of this study was to evaluate whether dosimetric sparing of uninvolved normal tissues, including skin/subcutaneous flaps , affects acute and late toxicities in preoperative image‐guided intensity‐modulated radiatio…
View article: Outcomes and prognostic factors in primary intrathoracic soft tissue sarcoma
Outcomes and prognostic factors in primary intrathoracic soft tissue sarcoma Open
Despite a small sample, this is the largest clinical cohort on intrathoracic soft tissue sarcomas, which carry high local and distant recurrence risks. Worse outcomes were linked to age >65 years, metastatic presentation, higher grade, and…
View article: Medical Student Perceptions of the Barriers to Entering Orthopaedic Surgery Differ by Gender
Medical Student Perceptions of the Barriers to Entering Orthopaedic Surgery Differ by Gender Open
Background The value of gender representation has been increasingly recognised in medicine, yet women represent only 13.6% of orthopaedic surgeons in Canada. The primary objective of this study was to determine barriers identified by medic…
View article: The utility of intraoperative marrow margin frozen section in extremity bone sarcoma resection
The utility of intraoperative marrow margin frozen section in extremity bone sarcoma resection Open
Background and Objectives Intraoperative frozen section analysis is commonly used to evaluate marrow margins during extremity bone sarcoma resections, but its efficacy in the era of magnetic resonance imaging is debated. This study aimed t…
View article: Tranexamic acid use in sarcoma surgery patients: A systematic review and meta‐analysis
Tranexamic acid use in sarcoma surgery patients: A systematic review and meta‐analysis Open
Introduction Perioperative bleeding increases morbidity and mortality in sarcoma patients. Tranexamic acid (TXA), an antifibrinolytic, is widely utilized in non‐sarcoma orthopaedic surgeries, but its adoption in sarcoma surgery is hindered…
View article: Obesity increases the risk of major wound complications following pelvic resection for bone sarcoma
Obesity increases the risk of major wound complications following pelvic resection for bone sarcoma Open
Background Given the paucity of data, the objective of this study is to evaluate the association between obesity and major wound complications following pelvic bone sarcoma surgery specifically. Methods Patients who underwent pelvic resect…
View article: Does Freehand, Patient-specific Instrumentation or Surgical Navigation Perform Better for Allograft Reconstruction After Tumor Resection? A Preclinical Synthetic Bone Study
Does Freehand, Patient-specific Instrumentation or Surgical Navigation Perform Better for Allograft Reconstruction After Tumor Resection? A Preclinical Synthetic Bone Study Open
Background Joint-sparing resection of periarticular bone tumors can be challenging because of complex geometry. Successful reconstruction of periarticular bone defects after tumor resection is often performed with structural allografts to …
View article: Active surveillance of diffuse-type tenosynovial giant cell tumors: A retrospective, multicenter cohort study
Active surveillance of diffuse-type tenosynovial giant cell tumors: A retrospective, multicenter cohort study Open
Active surveillance can be considered adequate for selected therapy naïve D-TGCT patients. Although follow-up data was limited, almost two-thirds of the patients remained progression-free, and 69 % did not need treatment during the follow-…
C-CASE 2023: Promoting Excellence in Surgical Education01. Near-peer tutoring: an effective adjunct for virtual anatomy learning02. Surgical Exploration and Discovery: perspectives on student-led debriefs in undergraduate surgical education03. How are emotions of medical residents and faculty in general surgery affected by new assessment mandates implemented in medical education?04. Equity, diversity and inclusion in medical residency: a Web-based analysis of Canadian PGME efforts05. The use of virtual patient case simulations in surgical postgraduate teaching innovations06. Outcomes of the Canadian Orthopaedic Surgery Medical Education Course07. Educational effectiveness of social media as a continuing professional development intervention among practising surgeons: a systematic review08. Factors influencing medical students’ decision to pursue a career in surgery in North America: a systematic review09. Improving operating room teamwork: Do current strategies offer actionable solutions?10. Affective influence on lumbar laminectomy performance on a virtual reality spine simulator11. Exploring the shifting landscape in the match outcomes of women applying to surgical residency programs in Canada: Have we achieved equity?12. Exploring residents’ emotion-regulation strategies and their effectiveness in team-based surgical simulations13. Impact of an educational workshop for medical student surgical clerkship rotation preparation14. McGill Surgical Exploration and Discovery: impact on medical students’ perception and skills in surgery15. Does BlackBox Explorer Technology improve operative teaching for surgical residents?16. The impact of a deceased donor organ procurement workshop on surgical transplant fellows’ confidence and competence17. Vascular anastomosis workshop improves general surgery residents’ confidence and competence18. A comparative analysis of video-based versus text-based learning resources for Foley catheter insertion and the implications for medical student procedural skills training: a pilot study19. Improving assessment and training in craniosynostosis: the role of interactive 3-D models and multimodal e-learning20. Anatomy of a strategic plan for education: driving innovation in McMaster’s Division of Cardiac Surgery21. Optimizing the learner’s role in feedback: development of a feedback-preparedness online application for medical students in the clinical setting22. Trainee response to artificial intelligent tutor instruction in surgical simulation23. Promoting diversity in surgery through UofC UpSurge24. Evaluating the benefit of a novel surgical robotic training workshop for general surgery and subspecialty trainees in Canada25. Undergraduate surgery learning objectives: illuminating discrepancies among Canadian medical schools26. Cerebral corticectomy in ex-vivo calf brain model: face and content validation27. Validating a virtual simulation tool for local and regional flap reconstruction in the head and neck28. The impact of a surgical boot camp and near-peer teaching on the acquisition of basic surgical skills in medical students transitioning to clerkship29. Evaluating the impact of the MLASE checklist on surgical training literature involving machine learning and virtual reality: a comparative analysis30. Exploring the impact of LearnENT’s social media as a powerful tool in OHNS medical education31. MiHolo, a holographic training tool for minimally invasive mitral valve repair surgery32. Evaluating the impact of medical students’ participation in telephone visits for patients with breast cancer: a pilot study33. The importance of understanding the personalities of surgeons when choosing a career: medical students’ perspectives34. A conversation on the current state of diversity, equity and inclusion in surgery35. Current state of female and BIPOC representation in Canadian medical education administration leadership36. What’s in a name? The development of trust and familiarity in dynamic interprofessional operating room teams37. Development and pilot of a plastic and reconstructive surgery case-based learning curriculum38. Women in surgery: a qualitative study of gendered experiences within everyday surgical life39. An interdisciplinary complex airway crisis resource management simulation training module for otolaryngology residents: a longitudinal experience40. Assessing the accuracy of responses by ChatGPT to questions regarding pediatric surgery Open
# 01. Near-peer tutoring: an effective adjunct for virtual anatomy learning {#article-title-2} The start of the COVID-19 pandemic caused a shift in medical education from the classroom to the virtual setting. This abrupt change led to an i…
View article: Gender Representation in Major Orthopaedic Surgery Meetings
Gender Representation in Major Orthopaedic Surgery Meetings Open
Background: Orthopaedic surgery suffers from gender disparity, and annual conferences are visible opportunities to quantify gender representation within a field. Therefore, the purpose of this manuscript was to investigate the prevalence o…
View article: Reconstructive Allograft Preparation for Long Bone Intercalary Segments After Tumor Resections
Reconstructive Allograft Preparation for Long Bone Intercalary Segments After Tumor Resections Open
Background: The Reconstructive Allograft Preparation by Toronto Sarcoma (RAPTORS) protocol is reliable and reproducible without substantially adding to the surgical reconstruction time or cost. Our technique includes clearance of debris, l…
View article: One-Stage Synovectomies Result in Improved Short-Term Outcomes Compared to Two-Stage Synovectomies of Diffuse-Type Tenosynovial Giant Cell Tumor (D-TGCT) of the Knee: A Multicenter, Retrospective, Cohort Study
One-Stage Synovectomies Result in Improved Short-Term Outcomes Compared to Two-Stage Synovectomies of Diffuse-Type Tenosynovial Giant Cell Tumor (D-TGCT) of the Knee: A Multicenter, Retrospective, Cohort Study Open
Diffuse-type tenosynovial giant cell tumors’ (D-TGCTs) intra- and extra-articular expansion about the knee often necessitates an anterior and posterior surgical approach to facilitate an extensive synovectomy. There is no consensus on whet…
View article: Clinico-demographic characteristics and outcomes of radiation-induced sarcomas (RIS): a CanSaRCC study
Clinico-demographic characteristics and outcomes of radiation-induced sarcomas (RIS): a CanSaRCC study Open
Background: Radiation-induced sarcomas (RIS) tend to have aggressive behaviour and because of their rarity, the most appropriate management for these malignancies is uncertain. Objectives: Using the Canadian Sarcoma Research and Clinical C…
C-CASE 2022: Competence to Excellence01. The Queen Bee phenomenon in Canadian surgical subspecialties: an evaluation of gender biases in the resident training environment02. Barriers to surgical peer coaching — What have we learned, and where do we go from here?03. Shared decision-making and evidence-based medicine: Pivotal or trivial to patient care in orthopedic trauma?04. Immersive virtual reality and cadaveric bone are equally effective in skeletal anatomy education: a randomized crossover noninferiority trial05. Development of simulators for decentralized simulation-based education IO training using design thinking and Delphi — a novel approach06. The impact of feedback on laparoscopic skills for surgical residents during COVID-1907. The role of collaborative feedback and remote practice in the acquisition of suturing skills by medical students at Université de Montréal08. Efficacy testing of an affordable and realistic small bowel simulator for hand-sewn anastomosis09. The LASER rating scale: a new teaching tool in otolaryngology10. Virtual patient case simulations: their role in undergraduate and postgraduate surgical training11. Evaluating the effectiveness of video-assisted informed consent in surgery: a systematic review12. Communication patterns in the cardiac surgery operating room are affected by task difficulty: a simulation model13. Improving adherence to postcall departure guidelines in orthopedics: a quality-improvement initiative14. Increasing familiarity among team members helps to reduce laparoscopic procedure time15. The effectiveness of a self-directed online learning module on trainee knowledge and confidence during plastic surgery clinical rotations16. Implementing an orientation handbook before a surgical rotation in urology17. An examination of equity-related experiences of surgical trainees at academic centres across Ontario: design of a targeted needs assessment18. Viewing differences between experts and trainees: implication for surgical education19. Assessment of medical student exposure to and satisfaction with surgical subspecialty education20. Assessment of student exposure to climate impacts of surgical personal protective equipment in the undergraduate medical curriculum21. Virtual reality simulation for the middle cranial fossa approach — a face, content and construct validation study22. Evaluating the Canadian Orthopaedic Surgery Medical Education Course (COSMEC)23. Subpial resection in a novel ex vivo calf brain epilepsy simulation model24. Effectiveness of the Eyesi augmented reality simulator for ophthalmology trainees: a systematic review and meta-analysis25. Learning beyond the objectives: an evidence-based analysis of AI-selected competencies in surgical simulation training26. Virtual compared with in-person surgical grand rounds: participants’ perceptions, preferences and directions for the future27. Quality of narrative feedback for entrustable professional activities assessed in the operating room: analysis of 4. years of assessments in the surgical foundations curriculum at Queen’s University28. SimOscopy: an accessible 3D-printed and laser-cut laparoscopic surgical simulator developed for a mobile device29. A debriefing tool to acquire nontechnical skills in trauma courses30. Capacity building using a hub-and-spokes model to produce customizable simulators for surgical education31. Exploring skin tone diversity in a plastic surgery resident education curriculum32. Video-based assessments of thoracic surgery trainees’ operative skills as adjuncts in competency-based medical education33. How do you feel? An examination of team leaders’ and members’ emotions in surgical simulations34. Comparing the efficacy of a real-time intelligent coaching system to human expert instruction in surgical technical skills training: randomized controlled trial35. Empowering women to pursue surgery: launching a pilot gender-congruent mentorship program for medical students36. Affective and cognitive responses to a virtual reality spine simulator37. Immersive virtual reality for patient-specific preoperative planning: a systematic review38. The categorization of surgical problems by junior and senior medical students39. The application of microlearning modules in surgical education to enhance procedural skills and surgical training40. Authorship gender disparity and trends in female authorship in 5 high-impact orthopedic journals from 2002 to 202241. The landscape of Canadian academic surgery: analysis of gender representation, academic rank, and research productivity Open
# 01. The Queen Bee phenomenon in Canadian surgical subspecialties: an evaluation of gender biases in the resident training environment {#article-title-2} The Queen Bee phenomenon describes the behavioural response that occurs when women a…
View article: <scp>ZFP64::NCOA3</scp> gene fusion defines a novel subset of spindle cell rhabdomyosarcoma
<span>ZFP64::NCOA3</span> gene fusion defines a novel subset of spindle cell rhabdomyosarcoma Open
Spindle cell rhabdomyosarcoma represents a rare neoplasm characterized by monomorphic spindle cells with a fascicular architecture and variable skeletal muscle differentiation. Following incidental identification of a ZFP64::NCOA3 gene fus…
View article: How Do the Outcomes of Radiation-Associated Pelvic and Sacral Bone Sarcomas Compare to Primary Osteosarcomas following Surgical Resection?
How Do the Outcomes of Radiation-Associated Pelvic and Sacral Bone Sarcomas Compare to Primary Osteosarcomas following Surgical Resection? Open
Radiation-associated sarcoma of the pelvis and/or sacrum (RASB) is a rare but challenging disease process associated with a poor prognosis. We hypothesized that patients with RASB would have worse surgical and oncologic outcomes than patie…
View article: Automatic Registration and Error Color Maps to Improve Accuracy for Navigated Bone Tumor Surgery Using Intraoperative Cone-Beam CT
Automatic Registration and Error Color Maps to Improve Accuracy for Navigated Bone Tumor Surgery Using Intraoperative Cone-Beam CT Open
Background: Computer-assisted surgery (CAS) can improve surgical precision in orthopaedic oncology. Accurate alignment of the patient’s imaging coordinates with the anatomy, known as registration, is one of the most challenging aspects of …
View article: Expanding the spectrum of mesenchymal neoplasms with <i>NR1D1</i>‐rearrangement
Expanding the spectrum of mesenchymal neoplasms with <i>NR1D1</i>‐rearrangement Open
Undifferentiated mesenchymal neoplasms can be morphologically subclassified based on cell shape; epithelioid tumors may be diagnostically challenging, particularly since they can show morphologic and immunohistochemical overlap with epithe…