Peter Choong
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View article: Mechanical reinforcement and growth factor delivery strategies for <i>in situ</i> cartilage repair
Mechanical reinforcement and growth factor delivery strategies for <i>in situ</i> cartilage repair Open
In situ cartilage engineering aims to repair damaged cartilage within the body by using biomaterials such as hydrogels, often loaded with regenerative cells to support tissue formation at the injury site. Hydrogels are promising candidates…
View article: Predicting Outcomes of Periprosthetic Joint Infection Treated With Debridement, Antibiotics, and Implant Retention: An External Validation of the KLIC (Kidney, Liver, Index Surgery, Cemented Prosthesis, C-Reactive Protein) Score
Predicting Outcomes of Periprosthetic Joint Infection Treated With Debridement, Antibiotics, and Implant Retention: An External Validation of the KLIC (Kidney, Liver, Index Surgery, Cemented Prosthesis, C-Reactive Protein) Score Open
The KLIC score has a limited ability to discriminate between patients who fail treatment with DAIR and those who do not. This was consistent across patients who had early and late acute infections. Further work is needed to improve its per…
View article: RWD280 THE LONG-TERM EFFECTS OF OPIOID USE BEFORE TOTAL JOINT REPLACEMENT SURGERY: A DOSE-RESPONSE TRIAL EMULATION USING NEW ZEALAND LINKED ADMINISTRATIVE DATA
RWD280 THE LONG-TERM EFFECTS OF OPIOID USE BEFORE TOTAL JOINT REPLACEMENT SURGERY: A DOSE-RESPONSE TRIAL EMULATION USING NEW ZEALAND LINKED ADMINISTRATIVE DATA Open
View article: Clinical prediction models to guide treatment of periprosthetic joint infections: a systematic review and meta-analysis
Clinical prediction models to guide treatment of periprosthetic joint infections: a systematic review and meta-analysis Open
Clinicians should be aware of limitations in the methods used to develop available models to predict outcomes of PJI. As no models have consistently demonstrated adequate performance across external validation studies, it remains unclear w…
View article: MonitOring the health trajectory of patients with kNee osteoarthritis referred for orthopaedic opinion: Protocol for the MOTION parallel cohort-implementation study
MonitOring the health trajectory of patients with kNee osteoarthritis referred for orthopaedic opinion: Protocol for the MOTION parallel cohort-implementation study Open
Approved by St Vincent's Hospital Melbourne Human Research Ethics Committee (HREC 251/21). Findings will be disseminated to stakeholders including via conferences, peer-reviewed journals, and social and mainstream media.
View article: Advanced topology optimisation for porous hip Implants: Bridging in silico models and in vitro tests
Advanced topology optimisation for porous hip Implants: Bridging in silico models and in vitro tests Open
This paper proposes a Floating Projection Topology Optimisation (FPTO) algorithm with ersatz material model and multiple constraints for smooth boundary implant design to reduce stress shielding effect. With FPTO technique, it is expected …
View article: Association between glucagon‐like peptide‐1 receptor agonist use and peri‐operative pulmonary aspiration: a systematic review and meta‐analysis
Association between glucagon‐like peptide‐1 receptor agonist use and peri‐operative pulmonary aspiration: a systematic review and meta‐analysis Open
Summary Introduction Glucagon‐like peptide‐1 receptor agonists are known to delay gastric emptying; however, the association between glucagon‐like peptide‐1 receptor agonist use and peri‐operative pulmonary aspiration risk is not known. Th…
View article: Willingness to participate in placebo-controlled surgical trials of the knee
Willingness to participate in placebo-controlled surgical trials of the knee Open
Aims Surgeon and patient reluctance to participate are potential significant barriers to conducting placebo-controlled trials of orthopaedic surgery. Understanding the preferences of orthopaedic surgeons and patients regarding the design o…
View article: Association Between Glucagon-like Peptide-1 Receptor Agonist Use and Perioperative Aspiration: A Systematic Review and Meta-Analysis
Association Between Glucagon-like Peptide-1 Receptor Agonist Use and Perioperative Aspiration: A Systematic Review and Meta-Analysis Open
Summary Background Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are known to slow gastric emptying, however the association between GLP-1 RA use and perioperative aspiration risk is not known. This systematic review and meta-analy…
View article: Feasibility and barriers to rapid establishment of patient-derived primary osteosarcoma cell lines in clinical management
Feasibility and barriers to rapid establishment of patient-derived primary osteosarcoma cell lines in clinical management Open
View article: Finite element analysis of patient-specific additive-manufactured implants
Finite element analysis of patient-specific additive-manufactured implants Open
Introduction: Bone tumors, characterized by diverse locations and shapes, often necessitate surgical excision followed by custom implant placement to facilitate targeted bone reconstruction. Leveraging additive manufacturing, patient-speci…
View article: Fixation strength of conformal additively manufactured Ti6Al4V implants in large animal model
Fixation strength of conformal additively manufactured Ti6Al4V implants in large animal model Open
Additive manufacturing (AM) enables patient-specific lattice-based implants with porosity engineered to encourage bone ingrowth and to mimic bone’s mechanical stiffness. The strength of the bone-implant interface can be measured through a …
View article: The Orthopaedic Device Infection Network: Building an Evidence Base for the Treatment of Periprosthetic Joint Infection Through International Collaboration
The Orthopaedic Device Infection Network: Building an Evidence Base for the Treatment of Periprosthetic Joint Infection Through International Collaboration Open
View article: Predictive Tool Use and Willingness for Surgery in Patients With Knee Osteoarthritis
Predictive Tool Use and Willingness for Surgery in Patients With Knee Osteoarthritis Open
Importance Despite the increasing number of tools available to predict the outcomes of total knee arthroplasty (TKA), the effect of these predictive tools on patient decision-making remains uncertain. Objective To assess the effect of an o…
View article: Influences on clinical trial participation: Enhancing recruitment through a gender lens - A scoping review
Influences on clinical trial participation: Enhancing recruitment through a gender lens - A scoping review Open
The relationship between factors influencing willingness to participate in clinical trials is complex. The influence of gender on willingness to participate, while important, may be moderated by other factors including socioeconomic status…
View article: Table of Contents
Table of Contents Open
View article: Discrete-Target Prosthesis Control Using Uncertainty-Aware Classification for Smooth and Efficient Gross Arm Movement
Discrete-Target Prosthesis Control Using Uncertainty-Aware Classification for Smooth and Efficient Gross Arm Movement Open
Current control approaches for gross prosthetic arm movement mainly regulate movement over a continuous range of target poses. However, these methods suffer from output fluctuation caused by input signal variations during gross arm movemen…
View article: Improving quality of care in total knee arthroplasty using risk prediction: a narrative review of predictive models and factors associated with their implementation in clinical practice
Improving quality of care in total knee arthroplasty using risk prediction: a narrative review of predictive models and factors associated with their implementation in clinical practice Open
View article: The long-term impacts of opioid use before and after joint arthroplasty: matched cohort analysis of New Zealand linked register data
The long-term impacts of opioid use before and after joint arthroplasty: matched cohort analysis of New Zealand linked register data Open
Background Opioids are commonly used both before and after total joint arthroplasty (TJA). Objective The objective of this study was to estimate the long-term effects of pre- and perioperative opioid use in patients undergoing TJA. Methods…
View article: Strategic Usability and Response in Ecommerce Marketing: A Framework and Investigation
Strategic Usability and Response in Ecommerce Marketing: A Framework and Investigation Open
In the literature usability is presented as an objective standard to which firms aspire to assist in the consumer decision-making process. In this paper, we introduce the concept of strategic usability, which we define as the variation of …
View article: Does a consumer co‐designed infographic increase knowledge of physical activity after total knee joint replacement? A randomised controlled trial
Does a consumer co‐designed infographic increase knowledge of physical activity after total knee joint replacement? A randomised controlled trial Open
Purpose To determine if a consumer co‐designed infographic increased knowledge of physical activity and self‐efficacy for exercise after total knee joint replacement surgery. Methods Forty‐four adults with primary knee joint replacement su…
View article: Mortality, patient-reported outcome measures, and the health economic burden of prosthetic joint infection
Mortality, patient-reported outcome measures, and the health economic burden of prosthetic joint infection Open
Prosthetic joint infection (PJI) is one of the most devastating complications for a patient following arthroplasty. This scoping review aims to evaluate the burden of PJI on individual patients and the healthcare system regarding the morta…
View article: Patients’ Views on AI for Risk Prediction in Shared Decision-Making for Knee Replacement Surgery: Qualitative Interview Study
Patients’ Views on AI for Risk Prediction in Shared Decision-Making for Knee Replacement Surgery: Qualitative Interview Study Open
Background The use of artificial intelligence (AI) in decision-making around knee replacement surgery is increasing, and this technology holds promise to improve the prediction of patient outcomes. Ambiguity surrounds the definition of AI,…
View article: Electronic medical records—a disappointing mirage for clinicians and research
Electronic medical records—a disappointing mirage for clinicians and research Open
View article: The Regulatory Challenge of 3D Bioprinting
The Regulatory Challenge of 3D Bioprinting Open
New developments in additive manufacturing and regenerative medicine have the potential to radically disrupt the traditional pipelines of therapy development and medical device manufacture. These technologies present a challenge for regula…
View article: Broken Machines or Active Bodies? Part 3. Five Recommendations to Shift the Way Clinicians Communicate With People Who Are Seeking Care for Osteoarthritis
Broken Machines or Active Bodies? Part 3. Five Recommendations to Shift the Way Clinicians Communicate With People Who Are Seeking Care for Osteoarthritis Open
SYNOPSIS: In parts 1 and 2 of this series, we highlighted the dominant impairment way of talking about osteoarthritis: talking that frames osteoarthritis as a disease of cartilage worsened by physical activity that can only be “cured” by r…
View article: What are the core recommendations for gout management in first line and specialist care? Systematic review of clinical practice guidelines
What are the core recommendations for gout management in first line and specialist care? Systematic review of clinical practice guidelines Open
Background Gout is the most common inflammatory arthritis, increasing in prevalence and burden. Of the rheumatic diseases, gout is the best-understood and potentially most manageable condition. However, it frequently remains untreated or p…
View article: Predicting 30-day readmission following total knee arthroplasty using machine learning and clinical expertise applied to clinical administrative and research registry data in an Australian cohort
Predicting 30-day readmission following total knee arthroplasty using machine learning and clinical expertise applied to clinical administrative and research registry data in an Australian cohort Open
View article: Broken Machines or Active Bodies? Part 2. How People Talk About Osteoarthritis and Why Clinicians Need to Change the Conversation
Broken Machines or Active Bodies? Part 2. How People Talk About Osteoarthritis and Why Clinicians Need to Change the Conversation Open
SYNOPSIS: How people talk about osteoarthritis may impact outcomes, including uptake of guideline recommendations related to activity-based lifestyles and interventions. In this editorial, we describe 2 key ways of talking, based on findin…
View article: Issue Information ‐ Editorial Board and TOC
Issue Information ‐ Editorial Board and TOC Open