Peter Covens
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View article: Optimised solid-phase extraction of 211At: Activity balance of 211At, 210At and 210Po after wet chemistry target dissolution
Optimised solid-phase extraction of 211At: Activity balance of 211At, 210At and 210Po after wet chemistry target dissolution Open
International audience
View article: Optimizing the Safety and Efficacy of Bio-Radiopharmaceuticals for Cancer Therapy
Optimizing the Safety and Efficacy of Bio-Radiopharmaceuticals for Cancer Therapy Open
The precise delivery of cytotoxic radiation to cancer cells through the combination of a specific targeting vector with a radionuclide for targeted radionuclide therapy (TRT) has proven valuable for cancer care. TRT is increasingly being c…
View article: Supplementary Data from Preclinical Evaluation of <sup>225</sup>Ac-Labeled Single-Domain Antibody for the Treatment of HER2<sup>pos</sup> Cancer
Supplementary Data from Preclinical Evaluation of <sup>225</sup>Ac-Labeled Single-Domain Antibody for the Treatment of HER2<sup>pos</sup> Cancer Open
Supplementary Data from Preclinical Evaluation of 225Ac-Labeled Single-Domain Antibody for the Treatment of HER2pos Cancer
View article: Data from Preclinical Evaluation of <sup>225</sup>Ac-Labeled Single-Domain Antibody for the Treatment of HER2<sup>pos</sup> Cancer
Data from Preclinical Evaluation of <sup>225</sup>Ac-Labeled Single-Domain Antibody for the Treatment of HER2<sup>pos</sup> Cancer Open
Human epidermal growth factor receptor type 2 (HER2) is overexpressed in various cancers; thus, HER2-targeting single-domain antibodies (sdAb) could offer a useful platform for radioimmunotherapy. In this study, we optimized the labeling o…
View article: Data from Preclinical Evaluation of <sup>225</sup>Ac-Labeled Single-Domain Antibody for the Treatment of HER2<sup>pos</sup> Cancer
Data from Preclinical Evaluation of <sup>225</sup>Ac-Labeled Single-Domain Antibody for the Treatment of HER2<sup>pos</sup> Cancer Open
Human epidermal growth factor receptor type 2 (HER2) is overexpressed in various cancers; thus, HER2-targeting single-domain antibodies (sdAb) could offer a useful platform for radioimmunotherapy. In this study, we optimized the labeling o…
View article: Supplementary Data from Preclinical Evaluation of <sup>225</sup>Ac-Labeled Single-Domain Antibody for the Treatment of HER2<sup>pos</sup> Cancer
Supplementary Data from Preclinical Evaluation of <sup>225</sup>Ac-Labeled Single-Domain Antibody for the Treatment of HER2<sup>pos</sup> Cancer Open
Supplementary Data from Preclinical Evaluation of 225Ac-Labeled Single-Domain Antibody for the Treatment of HER2pos Cancer
View article: Finger doses due to <sup>68</sup>Ga-labelled pharmaceuticals in PET departments—results of a multi-centre pilot study
Finger doses due to <sup>68</sup>Ga-labelled pharmaceuticals in PET departments—results of a multi-centre pilot study Open
Introduction: Although the use of 68 Ga has increased substantially in nuclear medicine over the last decade, there is limited information available on occupational exposure due to 68 Ga. The purpose of this study is to determine the occup…
View article: Preclinical Evaluation of 225Ac-Labeled Single-Domain Antibody for the Treatment of HER2pos Cancer
Preclinical Evaluation of 225Ac-Labeled Single-Domain Antibody for the Treatment of HER2pos Cancer Open
Human epidermal growth factor receptor type 2 (HER2) is overexpressed in various cancers; thus, HER2-targeting single-domain antibodies (sdAb) could offer a useful platform for radioimmunotherapy. In this study, we optimized the labeling o…
View article: Assessment of mouse-specific pharmacokinetics in kidneys based on 131I activity measurements using micro-SPECT
Assessment of mouse-specific pharmacokinetics in kidneys based on 131I activity measurements using micro-SPECT Open
Background In order to acquire accurate drug pharmacokinetic information, which is required for tissue dosimetry, micro-SPECT must be quantitative to allow for an accurate assessment of radioligand activity in the relevant tissue. This stu…
View article: Review of extremity dosimetry in nuclear medicine
Review of extremity dosimetry in nuclear medicine Open
The exposure of the fingers is one of the major radiation protection concerns in nuclear medicine (NM). The purpose of this paper is to provide an overview of the exposure, dosimetry and protection of the extremities in NM. A wide range of…
View article: EURADOS Intercomparison on Compartmental Model for 18F-FDG Developed by Hays and Segall
EURADOS Intercomparison on Compartmental Model for 18F-FDG Developed by Hays and Segall Open
This report was originated from the analysis of the results of a joint EURADOS-EANM project about the assessment of the external radiation dose rate to comforters and caregivers exposed to patients undergoing nuclear medical diagnostics an…
View article: Assessment of Mouse-Specific Pharmacokinetics in Kidneys Based on 131I Activity Measurements Using Micro-SPECT
Assessment of Mouse-Specific Pharmacokinetics in Kidneys Based on 131I Activity Measurements Using Micro-SPECT Open
Background In order to acquire accurate drug pharmacokinetic information, such as that required for tissue dosimetry, micro-SPECT must be quantitative and allow an accurate assessment of radioligand activity in the relevant tissue. This st…
View article: An international multi-center investigation on the accuracy of radionuclide calibrators in nuclear medicine theranostics
An international multi-center investigation on the accuracy of radionuclide calibrators in nuclear medicine theranostics Open
Background: Personalized molecular radiotherapy based on theragnostics requires accurate quantification of the amount of radiopharmaceutical activity administered to patients both in diagnostic and therapeutic applications. This internatio…
View article: External Dose Rates from Nuclear Medicine Patients to Specific Patient-Carers Geometries - A computational approach
External Dose Rates from Nuclear Medicine Patients to Specific Patient-Carers Geometries - A computational approach Open
International audience
View article: An international multi-center investigation on the accuracy of radionuclide calibrators in nuclear medicine theranostics
An international multi-center investigation on the accuracy of radionuclide calibrators in nuclear medicine theranostics Open
Background: Personalized molecular radiotherapy based on theranostics requires accurate quantification of the amount of radiopharmaceutical activity administered to patients both in diagnostic and therapeutic applications. This internation…