Peter Dungel
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View article: From Lab to Workplace: Efficacy of Skin Protection Creams Against Hydrophobic Working Materials
From Lab to Workplace: Efficacy of Skin Protection Creams Against Hydrophobic Working Materials Open
Occupational dermatoses represent a significant challenge across numerous industries. Therefore, occupational skin protection creams are frequently used as a preventative measure, yet their efficacy, particularly against hydrophobic workin…
View article: Curation of non healing cephalic wound treated with pulsed red LED light therapy after split skin transplantation
Curation of non healing cephalic wound treated with pulsed red LED light therapy after split skin transplantation Open
Basal Cell Carcinoma (BCC) is one of the most common human skin cancers and usually occurs on sun-exposed areas of the body. This carcinoma represents a public health concern due to its aggressive local invasiveness.
View article: The Multifaceted Actions of PVP–Curcumin for Treating Infections
The Multifaceted Actions of PVP–Curcumin for Treating Infections Open
Curcumin is a natural compound that is considered safe and may have potential health benefits; however, its poor stability and water insolubility limit its therapeutic applications. Different strategies aim to increase its water solubility…
View article: Prospective Study on the Influence of Occupational Hand Protection Products on the Efficacy of Hand Disinfection
Prospective Study on the Influence of Occupational Hand Protection Products on the Efficacy of Hand Disinfection Open
Background: To prevent occupational skin diseases, employees are instructed to periodically apply hand protection products as a barrier to protect their hands from water, cleaning agents or other irritants. The aim of this work was to inve…
View article: Testing the effects of photobiomodulation on angiogenesis in a newly established CAM burn wound model
Testing the effects of photobiomodulation on angiogenesis in a newly established CAM burn wound model Open
Burn wounds are a common challenge for medical professionals. Current burn wound models hold several limitations, including a lack of comparability due to the heterogeneity of wounds and differences in individual wound healing. Hence, ther…
View article: The Influence of Photobiomodulation in the CAM Assay – Establishing a CAM burn wound model
The Influence of Photobiomodulation in the CAM Assay – Establishing a CAM burn wound model Open
Burn wounds are a common challenge for medical professionals. Current burn wound models hold several limitations, including a lack of comparability due to the heterogeneity of wounds and differences in individual wound healing. Hence, ther…
View article: Wavelength-Dependent Effects of Photobiomodulation for Wound Care in Diabetic Wounds
Wavelength-Dependent Effects of Photobiomodulation for Wound Care in Diabetic Wounds Open
Photobiomodulation, showing positive effects on wound healing processes, has been performed mainly with lasers in the red/infrared spectrum. Light of shorter wavelengths can significantly influence biological systems. This study aimed to e…
View article: Conventional and Pro-Inflammatory Pathways of Fibrinolytic Activation in Non-Traumatic Hyperfibrinolysis
Conventional and Pro-Inflammatory Pathways of Fibrinolytic Activation in Non-Traumatic Hyperfibrinolysis Open
Hyperfibrinolysis (HF) frequently occurs after severe systemic hypoperfusion during major trauma and out-of-hospital cardiac arrest (OHCA). In trauma-induced HF, hypoperfusion, the activation of protein C (APC), and the release of tissue p…
View article: Resistance of Bacteria toward 475 nm Blue Light Exposure and the Possible Role of the SOS Response
Resistance of Bacteria toward 475 nm Blue Light Exposure and the Possible Role of the SOS Response Open
The increase in antibiotic resistance represents a major global challenge for our health systems and calls for alternative treatment options, such as antimicrobial light-based therapies. Blue light has shown promising results regarding the…
View article: A Novel Artificial Intelligence-Based Approach for Quantitative Assessment of Angiogenesis in the Ex Ovo CAM Model
A Novel Artificial Intelligence-Based Approach for Quantitative Assessment of Angiogenesis in the Ex Ovo CAM Model Open
Angiogenesis is a highly regulated process. It promotes tissue regeneration and contributes to tumor growth. Existing therapeutic concepts interfere with different steps of angiogenesis. The quantification of the vasculature is of crucial …
View article: Shockwaves Increase In Vitro Resilience of Rhizopus oryzae Biofilm under Amphotericin B Treatment
Shockwaves Increase In Vitro Resilience of Rhizopus oryzae Biofilm under Amphotericin B Treatment Open
Acoustical biophysical therapies, including ultrasound, radial pressure waves, and shockwaves, have been shown to harbor both a destructive and regenerative potential depending on physical treatment parameters. Despite the clinical relevan…
View article: Novel 3D-Printed Cell Culture Inserts for Air–Liquid Interface Cell Culture
Novel 3D-Printed Cell Culture Inserts for Air–Liquid Interface Cell Culture Open
In skin research, widely used in vitro 2D monolayer models do not sufficiently mimic physiological properties. To replace, reduce, and refine animal experimentation in the spirit of ‘3Rs’, new approaches such as 3D skin equivalents (SE) ar…
View article: Antibody Seroprevalence and Rate of Asymptomatic Infections With SARS-CoV-2 in Austrian Hospital Personnel
Antibody Seroprevalence and Rate of Asymptomatic Infections With SARS-CoV-2 in Austrian Hospital Personnel Open
Context: On March 11, the World Health Organization (WHO) announced the current corona virus disease 2019 (COVID-19) outbreak as a pandemic. The first laboratory-confirmed case of COVID-19 in Austria was announced on February 27, 2020. Sin…
View article: Antibody seroprevalence and rate of asymptomatic infections with SARS-CoV-2 in Austrian hospital personnel
Antibody seroprevalence and rate of asymptomatic infections with SARS-CoV-2 in Austrian hospital personnel Open
Context On March 11, the World Health Organization (WHO) announced the current corona virus disease 2019 (COVID-19) outbreak as a pandemic. The first laboratory-confirmed case of COVID-19 in Austria was announced on February 27, 2020. Sinc…
View article: Cross-modality imaging of bisphosphonate-treated murine jawbones
Cross-modality imaging of bisphosphonate-treated murine jawbones Open
Based on a novel correlative multimodal imaging pipeline, we showed that the morphology of bisphosphonate-treated murine jawbones changed significantly after treatment with physical extracorporeal shockwave and photobiomodulation therapies.
View article: Photobiomodulation for Alzheimer’s Disease: Translating Basic Research to Clinical Application
Photobiomodulation for Alzheimer’s Disease: Translating Basic Research to Clinical Application Open
One of the challenges in translating new therapeutic approaches to the patient bedside lies in bridging the gap between scientists who are conducting basic laboratory research and medical practitioners who are not exposed to highly special…
View article: Mechanical Stimulation of Fibroblasts by Extracorporeal Shock Waves: Modulation of Cell Activation and Proliferation Through a Transient Proinflammatory Milieu
Mechanical Stimulation of Fibroblasts by Extracorporeal Shock Waves: Modulation of Cell Activation and Proliferation Through a Transient Proinflammatory Milieu Open
Extracorporeal shock waves (ESWTs) are “mechanical” waves, widely used in regenerative medicine, including soft tissue wound repair. Although already being used in the clinical practice, the mechanism of action underlying their biological …
View article: #neverforget - Photobiomodulation Against Alzheimer's Disease: A Systematic Review
#neverforget - Photobiomodulation Against Alzheimer's Disease: A Systematic Review Open
Alzheimer's disease affects an ever-increasing number of people in the aging population. Current treatment options are limited to a narrow time frame at the mild to moderate stage of dementia, and patients are confronted with the inevitabl…
View article: #neverforget - Photobiomodulation Against Alzheimer's Disease: A\n Systematic Review
#neverforget - Photobiomodulation Against Alzheimer's Disease: A\n Systematic Review Open
Alzheimer's disease affects an ever-increasing number of people in the aging\npopulation. Current treatment options are limited to a narrow time frame at the\nmild to moderate stage of dementia, and patients are confronted with the\ninevit…
View article: Photobiomodulation (PBM) promotes angiogenesis in-vitro and in chick embryo chorioallantoic membrane model
Photobiomodulation (PBM) promotes angiogenesis in-vitro and in chick embryo chorioallantoic membrane model Open
The application of light in various therapeutic settings known as Photobiomodulation (PBM) is well established. Indications are the improvement of wound healing and tissue regeneration, scarring, and perfusion as well as pain therapy. Tiss…
View article: Modelling physical resilience in ageing mice
Modelling physical resilience in ageing mice Open
Geroprotectors, a class of drugs targeting multiple deficits occurring with age, necessitate the development of new animal models to test their efficacy. The COST Action MouseAGE is a European network whose aim is to reach consensus on the…
View article: Pericellular Oxygen Monitoring during Low-Level Light Therapy in Cell Culture Using a Microsensor System
Pericellular Oxygen Monitoring during Low-Level Light Therapy in Cell Culture Using a Microsensor System Open
An electrochemical microsensor system to monitor the pericellular oxygen concentration of fibroblasts during low-level light therapy in vitro was developed. The system provides in-sight into the metabolism of the cells during and in conseq…