Peter Gooderham
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View article: Prophylaxis for venous thromboembolism in traumatic brain injury: protocol for a randomised controlled trial
Prophylaxis for venous thromboembolism in traumatic brain injury: protocol for a randomised controlled trial Open
Introduction Venous thromboembolism (VTE) is a common complication of traumatic brain injury (TBI) and is associated with increased morbidity and mortality. Low molecular weight heparin (LMWH) is recommended for prophylaxis against VTE aft…
View article: 51 LONG-TERM RADIOLOGICAL AND BIOCHEMICAL CONTROL OF FUNCTIONING PITUITARY ADENOMAS WITH FRACTIONATED STEREOTACTIC RADIATION THERAPY: A RETROSPECTIVE CASE SERIES
51 LONG-TERM RADIOLOGICAL AND BIOCHEMICAL CONTROL OF FUNCTIONING PITUITARY ADENOMAS WITH FRACTIONATED STEREOTACTIC RADIATION THERAPY: A RETROSPECTIVE CASE SERIES Open
OBJECTIVE This study examined long term radiological and biochemical control of functioning pituitary neuroendocrine tumors (PitNETs) treated with fractionated stereotactic radiotherapy. METHODS A retrospective case series was conducted on…
View article: 1 NATURAL HISTORY AND SURGICAL OUTCOMES OF SINGLE-CENTRE EXPERIENCE IN MANAGEMENT OF SPHENO-ORBITAL MENINGIOMAS
1 NATURAL HISTORY AND SURGICAL OUTCOMES OF SINGLE-CENTRE EXPERIENCE IN MANAGEMENT OF SPHENO-ORBITAL MENINGIOMAS Open
Spheno-orbital meningiomas (SOM) are intracranial tumours arising from the sphenoid wing. Common presentations include visual impairment, exophthalmos, and headache. Gross-total resection (GTR) is difficult due to anatomical complexity. Su…
View article: Emotional Lability as a Symptom of Extra-axial Posterior Fossa Tumors: a Case–Control Review of Neuroanatomy and Patient-Reported Quality of Life
Emotional Lability as a Symptom of Extra-axial Posterior Fossa Tumors: a Case–Control Review of Neuroanatomy and Patient-Reported Quality of Life Open
Introduction Emotional lability (EL), the uncontrollable and unmotivated expression of emotion, is a rare and distressing symptom of brainstem compression. In published case reports, EL from an extra-axial posterior fossa tumor was allevia…
View article: The impact of brain invasion criteria on the incidence and distribution of WHO grade 1, 2, and 3 meningiomas
The impact of brain invasion criteria on the incidence and distribution of WHO grade 1, 2, and 3 meningiomas Open
Background In 2016 brain invasion was added as a standalone diagnostic criterion for Grade 2 meningiomas in the WHO Classification of Brain Tumors. The aim of this study was to compare the incidence and distribution of meningiomas, and agr…
View article: The Unified Visual Function Scale Assessments Show Inter- and Intraobserver Agreement and Correlate with Patient Quality of Life in Skull Base Parasellar Tumors
The Unified Visual Function Scale Assessments Show Inter- and Intraobserver Agreement and Correlate with Patient Quality of Life in Skull Base Parasellar Tumors Open
Introduction The authors have previously described the Unified Visual Function Scale (UVFS). Here, we assessed intra- and interobserver reliability of the scale, and investigated correlations with patient quality of life (QoL). Methods Eig…
View article: Quantitative Optical Coherence Tomography Angiography in Patients with Moyamoya Vasculopathy: A Pilot Study
Quantitative Optical Coherence Tomography Angiography in Patients with Moyamoya Vasculopathy: A Pilot Study Open
Moyamoya (MM) disease is a chronic cerebrovascular disease that can lead to progressive stenosis of the terminal portions of the internal carotid arteries and their proximal branches. We sought to investigate and quantify retinal vascular …
View article: Brain Hypoxia Is Associated With Neuroglial Injury in Humans Post–Cardiac Arrest
Brain Hypoxia Is Associated With Neuroglial Injury in Humans Post–Cardiac Arrest Open
Rationale: Secondary brain hypoxia portends significant mortality in ischemic brain diseases; yet, our understanding of hypoxic ischemic brain injury (HIBI) pathophysiology in humans remains rudimentary. Objective: To quantify the impact o…
View article: Cost-effectiveness analysis in patients with an unruptured cerebral aneurysm treated with observation or surgery
Cost-effectiveness analysis in patients with an unruptured cerebral aneurysm treated with observation or surgery Open
OBJECTIVE The main goal of preventive treatment of unruptured intracranial aneurysms (UIAs) is to avoid the morbidity and mortality associated with aneurysmal subarachnoid hemorrhage. A comparison between the conservative approach and the …
View article: Intraparenchymal Neuromonitoring of Cerebral Fat Embolism Syndrome
Intraparenchymal Neuromonitoring of Cerebral Fat Embolism Syndrome Open
Objectives: We aimed to characterize the cerebrovascular physiology of cerebral fat embolism using invasive multimodal neuromonitoring. Data Sources: ICU, Vancouver General Hospital, Vancouver, BC, Canada. Study Selection: Case report. Dat…
View article: Functional Outcomes After Treatment of Posterior Inferior Cerebellar Artery Aneurysms
Functional Outcomes After Treatment of Posterior Inferior Cerebellar Artery Aneurysms Open
Objective Aneurysms of the posterior inferior cerebellar artery (PICA) are a rare cause of subarachnoid hemorrhage. Treatment for this type of aneurysm may be microsurgical clipping or endovascular. This decision is based on patient charac…
View article: Headache Outcomes After Treatment of Unruptured Intracranial Aneurysm
Headache Outcomes After Treatment of Unruptured Intracranial Aneurysm Open
Background and Purpose— While unruptured intracranial aneurysms may be discovered incidentally in the workup of chronic headache, it remains unclear whether their treatment ultimately impacts headache severity. We aim to conduct a systemat…
View article: The Burden of Brain Hypoxia and Optimal Mean Arterial Pressure in Patients With Hypoxic Ischemic Brain Injury After Cardiac Arrest*
The Burden of Brain Hypoxia and Optimal Mean Arterial Pressure in Patients With Hypoxic Ischemic Brain Injury After Cardiac Arrest* Open
Objectives: In patients at risk of hypoxic ischemic brain injury following cardiac arrest, we sought to: 1) characterize brain oxygenation and determine the prevalence of brain hypoxia, 2) characterize autoregulation using the pressure rea…
View article: CJN volume 45 issue 4 Cover and Front matter
CJN volume 45 issue 4 Cover and Front matter Open
An abstract is not available for this content so a preview has been provided. As you have access to this content, a full PDF is available via the ‘Save PDF’ action button.
View article: A Systematic Review of the Risks and Benefits of Venous Thromboembolism Prophylaxis in Traumatic Brain Injury
A Systematic Review of the Risks and Benefits of Venous Thromboembolism Prophylaxis in Traumatic Brain Injury Open
Background: Patients suffering from traumatic brain injury (TBI) are at increased risk of venous thromboembolism (VTE). However, initiation of pharmacological venous thromboprophylaxis (VTEp) may cause further intracranial hemorrhage. We r…
View article: Extracapsular Pituitary Macroadenoma Resection and Internal Carotid Artery Aneurysm Clipping via Endoscopic Endonasal Approach: Technical Description
Extracapsular Pituitary Macroadenoma Resection and Internal Carotid Artery Aneurysm Clipping via Endoscopic Endonasal Approach: Technical Description Open
Pituitary macroadenomas and internal carotid artery parasellar aneurysms are relatively common conditions that occur rarely in the same patient. All skull base surgeons should be aware of the potential of this dangerous and challenging coi…
View article: Adult Craniopharyngioma: Case Series, Systematic Review, and Meta-analysis
Adult Craniopharyngioma: Case Series, Systematic Review, and Meta-analysis Open
The optimal therapeutic approach for adult craniopharyngioma remains controversial. Some advocate for gross total resection (GTR), while others advocate for subtotal resection followed by adjuvant radiotherapy (STR + XRT). To conduct a sys…
View article: Reliability and Correlation with Quality of Life Outcomes of Unified Visual Function Scale
Reliability and Correlation with Quality of Life Outcomes of Unified Visual Function Scale Open
Background Historically, descriptions of visual acuity and visual field change following intracranial procedures have been very rudimentary. Clinicians and researchers have often used basic descriptions such as "improved," "worsened," and …
View article: A novel scale for describing visual outcomes in patients following resection of lesions affecting the optic apparatus: the Unified Visual Function Scale
A novel scale for describing visual outcomes in patients following resection of lesions affecting the optic apparatus: the Unified Visual Function Scale Open
OBJECTIVE Historically, descriptions of visual acuity and visual field change following intracranial procedures have been very rudimentary. Clinicians and researchers have often used basic descriptions, such as “improved,” “worsened,” and …
View article: CJN volume 44 issue 4 Cover and Front matter
CJN volume 44 issue 4 Cover and Front matter Open
An abstract is not available for this content so a preview has been provided. As you have access to this content, a full PDF is available via the ‘Save PDF’ action button.
View article: Implementation of Neurocritical Care Is Associated With Improved Outcomes in Traumatic Brain Injury
Implementation of Neurocritical Care Is Associated With Improved Outcomes in Traumatic Brain Injury Open
Background Traditionally, the delivery of dedicated neurocritical care (NCC) occurs in distinct NCC units and is associated with improved outcomes. Institution-specific logistical challenges pose barriers to the development of distinct NCC…
View article: Reversible Parkinsonism and Rapidly Progressive Dementia Due to Dural Arteriovenous Fistula: Case Series and Literature Review
Reversible Parkinsonism and Rapidly Progressive Dementia Due to Dural Arteriovenous Fistula: Case Series and Literature Review Open
Background Dural arteriovenous fistula ( dAVF ) rarely presents with a syndrome of reversible parkinsonism and rapidly progressive dementia, which has been described in 19 patients to date. However, its presenting features, pathophysiology…
View article: Dissociation of Early and Delayed Cerebral Infarction After Aneurysmal Subarachnoid Hemorrhage
Dissociation of Early and Delayed Cerebral Infarction After Aneurysmal Subarachnoid Hemorrhage Open
Background and Purpose— Cerebral infarction after aneurysmal subarachnoid hemorrhage is a significant cause of substantial morbidity and mortality. Because early and delayed cerebral infarction after aneurysmal subarachnoid hemorrhage may …
View article: Episodic hemilaryngopharyngeal spasm (HELPS) syndrome: case report of a surgically treatable novel neuropathy
Episodic hemilaryngopharyngeal spasm (HELPS) syndrome: case report of a surgically treatable novel neuropathy Open
The authors describe a novel cranial neuropathy manifesting with life-threatening episodic hemilaryngopharyngeal spasm (HELPS). A 50-year-old woman presented with a 4-year history of intermittent throat contractions, escalating to life-thr…