Peter Grice
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View article: High-physiological and supra-physiological 1,2-<sup>13</sup>C<sub>2</sub> glucose focal supplementation to the traumatised human brain
High-physiological and supra-physiological 1,2-<sup>13</sup>C<sub>2</sub> glucose focal supplementation to the traumatised human brain Open
How to optimise glucose metabolism in the traumatised human brain remains unclear, including whether injured brain can metabolise additional glucose when supplied. We studied the effect of microdialysis-delivered 1,2- 13 C 2 glucose at 4 a…
View article: CCDC 2153622: Experimental Crystal Structure Determination
CCDC 2153622: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2153619: Experimental Crystal Structure Determination
CCDC 2153619: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2163435: Experimental Crystal Structure Determination
CCDC 2163435: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2153621: Experimental Crystal Structure Determination
CCDC 2153621: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2153620: Experimental Crystal Structure Determination
CCDC 2153620: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Incorporation of a Phosphino(pyridine) Subcomponent Enables the Formation of Cages with Homobimetallic and Heterobimetallic Vertices
Incorporation of a Phosphino(pyridine) Subcomponent Enables the Formation of Cages with Homobimetallic and Heterobimetallic Vertices Open
Biological systems employ multimetallic assemblies to achieve a range of functions. Here we demonstrate the preparation of metal-organic cages that contain either homobimetallic or heterobimetallic vertices. These vertices are constructed …
View article: Phosphorus spectroscopy in acute TBI demonstrates metabolic changes that relate to outcome in the presence of normal structural MRI
Phosphorus spectroscopy in acute TBI demonstrates metabolic changes that relate to outcome in the presence of normal structural MRI Open
Metabolic dysfunction is a key pathophysiological process in the acute phase of traumatic brain injury (TBI). Although changes in brain glucose metabolism and extracellular lactate/pyruvate ratio are well known, it was hitherto unknown whe…
View article: Synthesis and characterisation of peroxypinic acids as proxies for highly oxygenated molecules (HOMs) in secondary organic aerosol
Synthesis and characterisation of peroxypinic acids as proxies for highly oxygenated molecules (HOMs) in secondary organic aerosol Open
Peroxy acids were recently found to be involved in new particle formation in the atmosphere and could also substantially contribute towards particle toxicity. However, a lack of suitable analytical methods for the detection and characteris…
View article: A Comparison of Oxidative Lactate Metabolism in Traumatically Injured Brain and Control Brain
A Comparison of Oxidative Lactate Metabolism in Traumatically Injured Brain and Control Brain Open
Metabolic abnormalities occur after traumatic brain injury (TBI). Glucose is conventionally regarded as the major energy substrate, although lactate can also be an energy source. We compared 3-13C lactate metabolism in TBI with "normal" co…
View article: Nephrectomy Avoided in a Patient with Lipid Poor Angiomylipoma with Radiological Features Suspicious for Renal Cell Carcinoma: A Case Report
Nephrectomy Avoided in a Patient with Lipid Poor Angiomylipoma with Radiological Features Suspicious for Renal Cell Carcinoma: A Case Report Open
Angiomyolipoma (AML) is a benign neoplasm that is easily mistaken for renal cell carcinoma (RCC) upon radiological investigation. The management of the two pathologies is significantly different, and so accurate diagnosis is vital. We repo…
View article: Online Quantification of Criegee Intermediates of α-Pinene Ozonolysis by Stabilization with Spin Traps and Proton-Transfer Reaction Mass Spectrometry Detection
Online Quantification of Criegee Intermediates of α-Pinene Ozonolysis by Stabilization with Spin Traps and Proton-Transfer Reaction Mass Spectrometry Detection Open
Biogenic alkenes, which are among the most abundant volatile organic compounds in the atmosphere, are readily oxidized by ozone. Characterizing the reactivity and kinetics of the first-generation products of these reactions, carbonyl oxide…
View article: Focally perfused succinate potentiates brain metabolism in head injury patients
Focally perfused succinate potentiates brain metabolism in head injury patients Open
Following traumatic brain injury, complex cerebral energy perturbations occur. Correlating with unfavourable outcome, high brain extracellular lactate/pyruvate ratio suggests hypoxic metabolism and/or mitochondrial dysfunction. We investig…