Peter H. Cable
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View article: Fate of arsenicals in mice carrying the human AS3MT gene exposed to environmentally relevant levels of arsenite in drinking water
Fate of arsenicals in mice carrying the human AS3MT gene exposed to environmentally relevant levels of arsenite in drinking water Open
Although mice are widely used to study adverse effects of inorganic arsenic (iAs), higher rates of iAs methylation in mice than in humans may limit their utility as a model organism. A recently created 129S6 mouse strain in which the Borcs…
View article: Placental Cadmium Levels Are Associated with Increased Preeclampsia Risk
Placental Cadmium Levels Are Associated with Increased Preeclampsia Risk Open
Environmental exposure to heavy metals is a potentially modifiable risk factor for preeclampsia (PE). Toxicologically, there are known interactions between the toxic metal cadmium (Cd) and essential metals such as selenium (Se) and zinc (Z…
View article: Gut Microbiome Perturbations Induced by Bacterial Infection Affect Arsenic Biotransformation
Gut Microbiome Perturbations Induced by Bacterial Infection Affect Arsenic Biotransformation Open
Exposure to arsenic affects large human populations worldwide, and has been associated with a long list of human diseases, including skin, bladder, lung, and liver cancers, diabetes, and cardiovascular disorders. In addition, there are lar…
View article: Gut Microbiome Phenotypes Driven by Host Genetics Affect Arsenic Metabolism
Gut Microbiome Phenotypes Driven by Host Genetics Affect Arsenic Metabolism Open
Large individual differences in susceptibility to arsenic-induced diseases are well-documented and frequently associated with different patterns of arsenic metabolism. In this context, the role of the gut microbiome in directly metabolizin…
View article: Placental Cadmium Levels Are Associated with Increased Preeclampsia Risk
Placental Cadmium Levels Are Associated with Increased Preeclampsia Risk Open
Environmental exposure to heavy metals is a potentially modifiable risk factor for preeclampsia (PE). Toxicologically, there are known interactions between the toxic metal cadmium (Cd) and essential metals such as selenium (Se) and zinc (Z…