Peter H. Hackett
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View article: Wilderness Medical Society Clinical Practice Guidelines for the Prevention and Treatment of Frostbite: 2024 Update
Wilderness Medical Society Clinical Practice Guidelines for the Prevention and Treatment of Frostbite: 2024 Update Open
The Wilderness Medical Society convened an expert panel to develop a set of evidence-based guidelines for the prevention and treatment of frostbite. We present a review of pertinent pathophysiology. We then discuss primary and secondary pr…
View article: Flying to high-altitude destinations: Is the risk of acute mountain sickness greater?
Flying to high-altitude destinations: Is the risk of acute mountain sickness greater? Open
Background Altitude sojourns increasingly attract individuals of all ages and different health statuses due to the appeal of high-altitude destinations worldwide and easy access to air travel. The risk of acute mountain sickness (AMS) when…
View article: Strengthening Altitude Knowledge: A Delphi Study to Define Minimum Knowledge of Altitude Illness for Laypersons Traveling to High Altitude
Strengthening Altitude Knowledge: A Delphi Study to Define Minimum Knowledge of Altitude Illness for Laypersons Traveling to High Altitude Open
Berendsen, Remco R., Peter Bärtsch, Buddha Basnyat, Marc Moritz Berger, Peter Hackett, Andrew M. Luks, Jean-Paul Richalet, Ken Zafren, Bengt Kayser, and the STAK Plenary Group. Strengthening altitude knowledge: a Delphi study to define min…
View article: Quality improvement project: to improve adherence to DVLA (driving and vehicle liscensing agency) guidance in the tyrone & fermanagh hospital acute inpatients ward
Quality improvement project: to improve adherence to DVLA (driving and vehicle liscensing agency) guidance in the tyrone & fermanagh hospital acute inpatients ward Open
Aims To reach 80% adherence to DVANI (Driving and Vehicle Agency Northern Ireland) guidance in acute inpatients ward, T&F Hospital Background This is a scale-up of a previous successful QI project on driving and Attention Deficit Hyperacti…
View article: The Reply
The Reply Open
View article: Using triallelic SNPs for determining parentage in North American yak (Bos grunniens) and estimating cattle (B. taurus) introgression
Using triallelic SNPs for determining parentage in North American yak (Bos grunniens) and estimating cattle (B. taurus) introgression Open
Background: Genetic testing for pedigree accuracy is critical for managing genetic diversity in North American (NA) yak (Bos grunniens), a population expanded mostly from imported zoological park specimens. DNA testing also enhances specie…
View article: Using triallelic SNPs for determining parentage in North American yak (Bos grunniens) and estimating cattle (B. taurus) introgression
Using triallelic SNPs for determining parentage in North American yak (Bos grunniens) and estimating cattle (B. taurus) introgression Open
Background: Genetic testing for pedigree accuracy is critical for managing genetic diversity in North American (NA) yak (Bos grunniens), a population expanded mostly from imported zoological park specimens. DNA testing also enhances specie…
View article: Continuous chromosome-scale haplotypes assembled from a single interspecies F1 hybrid of yak and cattle
Continuous chromosome-scale haplotypes assembled from a single interspecies F1 hybrid of yak and cattle Open
Background The development of trio binning as an approach for assembling diploid genomes has enabled the creation of fully haplotype-resolved reference genomes. Unlike other methods of assembly for diploid genomes, this approach is enhance…
View article: 0106 The Effects of Caffeine on Blood Pressure and Cognitive Performance in Hypoxic Conditions on the Slopes of Mt. Everest
0106 The Effects of Caffeine on Blood Pressure and Cognitive Performance in Hypoxic Conditions on the Slopes of Mt. Everest Open
Introduction 140 million people live above 2,400m worldwide. High altitude (HA) exposure can lead to sleep disruption, impaired cognitive performance, acute mountain sickness (AMS), elevated blood pressure (BP) and an increase in cardiovas…
View article: A Life at High Altitude: A Conversation With Todd Bull and Peter Hackett
A Life at High Altitude: A Conversation With Todd Bull and Peter Hackett Open
View article: Wilderness Medical Society Clinical Practice Guidelines for the Out-of-Hospital Evaluation and Treatment of Accidental Hypothermia: 2019 Update
Wilderness Medical Society Clinical Practice Guidelines for the Out-of-Hospital Evaluation and Treatment of Accidental Hypothermia: 2019 Update Open
To provide guidance to clinicians, the Wilderness Medical Society convened an expert panel to develop evidence-based guidelines for the out-of-hospital evaluation and treatment of victims of accidental hypothermia. The guidelines present t…
View article: Wilderness Medical Society Clinical Practice Guidelines for the Prevention and Treatment of Frostbite: 2019 Update
Wilderness Medical Society Clinical Practice Guidelines for the Prevention and Treatment of Frostbite: 2019 Update Open
The Wilderness Medical Society convened an expert panel to develop a set of evidence-based guidelines for prevention and treatment of frostbite. We present a review of pertinent pathophysiology. We then discuss primary and secondary preven…
View article: Wilderness Medical Society Clinical Practice Guidelines for the Prevention and Treatment of Acute Altitude Illness: 2019 Update
Wilderness Medical Society Clinical Practice Guidelines for the Prevention and Treatment of Acute Altitude Illness: 2019 Update Open
To provide guidance to clinicians about best preventive and therapeutic practices, the Wilderness Medical Society (WMS) convened an expert panel to develop evidence-based guidelines for prevention and treatment of acute mountain sickness, …
View article: Acute and Evolving MRI of High-Altitude Cerebral Edema: Microbleeds, Edema, and Pathophysiology
Acute and Evolving MRI of High-Altitude Cerebral Edema: Microbleeds, Edema, and Pathophysiology Open
MR imaging of high-altitude cerebral edema shows reversible WM edema, especially in the corpus callosum and subcortical WM. Recent studies have revealed hemosiderin deposition in WM long after high-altitude cerebral edema has resolved, pro…
View article: 0130 The Effects of Caffeine on Sleep in Hypoxic Conditions on the Slopes of Mt. Everest
0130 The Effects of Caffeine on Sleep in Hypoxic Conditions on the Slopes of Mt. Everest Open
140 million people live above 2,400m worldwide and even more are exposed to high altitude each year. High altitude has been reported to cause decrements in sleep including reduced total sleep time, reduced sleep efficiency, and reduced REM…
View article: The 2018 Lake Louise Acute Mountain Sickness Score
The 2018 Lake Louise Acute Mountain Sickness Score Open
Roach, Robert C., Peter H. Hackett, Oswald Oelz, Peter Bärtsch, Andrew M. Luks, Martin J. MacInnis, J. Kenneth Baillie, and The Lake Louise AMS Score Consensus Committee. The 2018 Lake Louise Acute Mountain Sickness Score. High Alt Med Bio…
View article: The STAR Data Reporting Guidelines for Clinical High Altitude Research
The STAR Data Reporting Guidelines for Clinical High Altitude Research Open
The STAR initiative, using the Delphi method, identified a set of key parameters essential for research and reporting in clinical HA medicine.
View article: In Response to Ibuprofen vs Acetaminophen in AMS Prevention by Kanaan et al
In Response to Ibuprofen vs Acetaminophen in AMS Prevention by Kanaan et al Open
For over 40 years the Nepal Himalaya has been a site for pioneering clinical trials investigating the understanding, prevention, and treatment of high altitude illness.1Hackett P.H. Rennie D. Levine H.D. The incidence, importance, and prop…
View article: Cerebral Edema in Chronic Mountain Sickness: a New Finding
Cerebral Edema in Chronic Mountain Sickness: a New Finding Open
View article: A New Proposal for Management of Severe Frostbite in the Austere Environment
A New Proposal for Management of Severe Frostbite in the Austere Environment Open
Despite advances in outdoor clothing and medical management of frostbite, individuals still experience catastrophic amputations. This is a particular risk for those in austere environments, due to resource limitations and delayed definitiv…
View article: General Medical Considerations for the Wilderness Adventurer: Medical Conditions That May Worsen With or Present Challenges to Coping With Wilderness Exposure
General Medical Considerations for the Wilderness Adventurer: Medical Conditions That May Worsen With or Present Challenges to Coping With Wilderness Exposure Open
Participation in wilderness and adventure sports is on the rise, and as such, practitioners will see more athletes seeking clearance to participate in these events. The purpose of this article is to describe specific medical conditions tha…