Peter Haldenwang
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View article: Dysregulated inflammation, oxidative stress, and protein quality control in diabetic HFpEF: unraveling mechanisms and therapeutic targets
Dysregulated inflammation, oxidative stress, and protein quality control in diabetic HFpEF: unraveling mechanisms and therapeutic targets Open
View article: Diabetes mellitus aggravates myocardial inflammation and oxidative stress in aortic stenosis: a mechanistic link to HFpEF features
Diabetes mellitus aggravates myocardial inflammation and oxidative stress in aortic stenosis: a mechanistic link to HFpEF features Open
Background Patients diagnosed with both aortic stenosis (AS) and diabetes mellitus (DM) encounter a distinctive set of challenges due to the interplay between these two conditions. This study aimed to investigate the effects of DM on the l…
View article: Reducing access complications in an interdisciplinary structural heart program
Reducing access complications in an interdisciplinary structural heart program Open
View article: Late open conversion: a reliable solution for endoleak management after endovascular aortic aneurysm repair – a single center experience and literature review
Late open conversion: a reliable solution for endoleak management after endovascular aortic aneurysm repair – a single center experience and literature review Open
Background/Objectives: Despite the efficacy of endovascular approaches for most secondary interventions post-endovascular aortic aneurysm repair (EVAR), a small proportion of patients need open conversion (OC) procedures. We shared our exp…
View article: Five-Year Trends of Vascular Disease-Related Amputations in Romania: A Retrospective Database Study
Five-Year Trends of Vascular Disease-Related Amputations in Romania: A Retrospective Database Study Open
Background/Objectives: Lower extremity amputations (LEAs) are a burdensome complication of peripheral artery disease (PAD) and/or arterial embolism and thrombosis (AET). We assessed the trends in PAD- and/or AET-related LEAs in Romania. Me…
View article: Minimally Invasive versus Conventional Aortic Root Surgery: Results of an Intermediate-Volume Center
Minimally Invasive versus Conventional Aortic Root Surgery: Results of an Intermediate-Volume Center Open
Background We evaluate the outcome of aortic root surgery via an upper J-shaped mini-sternotomy (MS) versus full sternotomy (FS) in an intermediate-volume center. Methods Between November 2011 and February 2019, 94 consecutive patients und…
View article: Transapical‐transcatheter aortic valve implantation in patients without transvascular options: Modified transapical approach
Transapical‐transcatheter aortic valve implantation in patients without transvascular options: Modified transapical approach Open
TA-TAVI is a safe method with low-rate procedural complications and shows good early and midterm outcomes in patients with extensive panarteriopathy for whom transfemoral and other alternative transvascular approaches are contraindicated o…
View article: Long-term Follow up after Transfemoral Transcatheter Aortic Valve Implantation in Lower Risk Patients Using the Balloon-Expandable Bioprosthesis: Gender-Dependent Outcomes
Long-term Follow up after Transfemoral Transcatheter Aortic Valve Implantation in Lower Risk Patients Using the Balloon-Expandable Bioprosthesis: Gender-Dependent Outcomes Open
Introduction: Long-term data on gender-related outcomes after transfemoral transcatheter aortic valve implantation (TF-TAVI) using newer generations heart valves in lower-risk patients are sparse. We aimed to evaluate gender-dependent long…
View article: Long-Term Outcomes After Transfemoral-Transcatheter Aortic Valve Implantation in Very Old Patients Using the Balloon-Expandable Bioprosthesis
Long-Term Outcomes After Transfemoral-Transcatheter Aortic Valve Implantation in Very Old Patients Using the Balloon-Expandable Bioprosthesis Open
Transcatheter aortic valve implantation (TAVI) can be safely performed in old patients. Increasing longevity raises often the question whether TAVI can be still useful for patients beyond a certain age limit. Data on long-term outcomes of …
View article: Early Results after Aortic Valve Replacement Using Last Generation Bioprosthetic Aortic Valve
Early Results after Aortic Valve Replacement Using Last Generation Bioprosthetic Aortic Valve Open
Introduction: Few data are available about the newest generation surgical bioprosthesis. We aimed to evaluate early clinical and hemodynamic outcomes after using the INSPIRIS RESILIA aortic valve (Edwards Lifesciences, Irvine, California, …
View article: Corrigendum to ‘Impact of the coronavirus disease 2019 (COVID-19) pandemic on the care of patients with acute and chronic aortic conditions’
Corrigendum to ‘Impact of the coronavirus disease 2019 (COVID-19) pandemic on the care of patients with acute and chronic aortic conditions’ Open
In the original version of this article, the first name of author Vitaly Sorokin was misspelled. This has now been corrected above and in the full article.
View article: Incidence and Impact of Routine Inflammatory Parameters on Outcome after Transcatheter Aortic Valve Replacement
Incidence and Impact of Routine Inflammatory Parameters on Outcome after Transcatheter Aortic Valve Replacement Open
Background. Previous research reported adverse clinical outcomes in association with systemic inflammation (SI) after transcatheter aortic valve replacement (TAVR). However, data characterizing the impact of SI, as reflected by postprocedu…
View article: Transapical transcatheter aortic valve implantation in patients with aortic diseases
Transapical transcatheter aortic valve implantation in patients with aortic diseases Open
OBJECTIVES Patients scheduled for transcatheter aortic valve implantation (TAVI) treatment frequently present with concomitant aortic diseases, in which case they are usually considered to be at high interventional risk and, in particular,…
View article: Transcatheter aortic valve replacement using the SAPIEN 3 valve versus surgical aortic valve replacement using the rapid deployment INTUITY valve: Midterm outcomes
Transcatheter aortic valve replacement using the SAPIEN 3 valve versus surgical aortic valve replacement using the rapid deployment INTUITY valve: Midterm outcomes Open
RD-SAVR was superior to TA-/TF-S3 in the PVL and PPI rates. We observed similar early outcomes and valve hemodynamics. The endocarditis was higher in the TAVR group.
View article: Impact of the coronavirus disease 2019 (COVID-19) pandemic on the care of patients with acute and chronic aortic conditions
Impact of the coronavirus disease 2019 (COVID-19) pandemic on the care of patients with acute and chronic aortic conditions Open
OBJECTIVES To evaluate the impact of the coronavirus disease 2019 (COVID-19) pandemic on acute and elective thoracic and abdominal aortic procedures. METHODS Forty departments shared their data on acute and elective thoracic and abdominal …
View article: Outcomes after transcatheter aortic valve replacement in older patients
Outcomes after transcatheter aortic valve replacement in older patients Open
View article: Undersizing but overfilling eliminates the gray zones of sizing for transcatheter aortic valve replacement with the balloon-expandable bioprosthesis
Undersizing but overfilling eliminates the gray zones of sizing for transcatheter aortic valve replacement with the balloon-expandable bioprosthesis Open
LIM-TAVR eliminates the gray zones of sizing and associated PVL, can improve THV-performance, reduce incidence of annular rupture and simplify the procedure especially in borderline cases.
View article: Enhanced Cardiomyocyte Function in Hypertensive Rats With Diastolic Dysfunction and Human Heart Failure Patients After Acute Treatment With Soluble Guanylyl Cyclase (sGC) Activator
Enhanced Cardiomyocyte Function in Hypertensive Rats With Diastolic Dysfunction and Human Heart Failure Patients After Acute Treatment With Soluble Guanylyl Cyclase (sGC) Activator Open
Our data show that sGC activator improves cardiomyocyte function, reduces inflammation and oxidative stress, improves sGC-PKG signaling, and normalizes hypertrophic kinases, indicating that it is a potential treatment option for HFpEF pati…
View article: Modulation of Titin-Based Stiffness in Hypertrophic Cardiomyopathy via Protein Kinase D
Modulation of Titin-Based Stiffness in Hypertrophic Cardiomyopathy via Protein Kinase D Open
The giant protein titin performs structure-preserving functions in the sarcomere and is important for the passive stiffness (Fpassive) of cardiomyocytes. Protein kinase D (PKD) enzymes play crucial roles in regulating myocardial…
View article: Valve-in-Valve After Edwards INTUITY Valve Implantation in Small Aortic Annulus
Valve-in-Valve After Edwards INTUITY Valve Implantation in Small Aortic Annulus Open
View article: Does Preoperative Computed Tomography Angiography Lead to an Increased Incidence of Postoperative Acute Kidney Injury Following Transcatheter Aortic Valve Implantation in Patients with Impaired Renal Function?
Does Preoperative Computed Tomography Angiography Lead to an Increased Incidence of Postoperative Acute Kidney Injury Following Transcatheter Aortic Valve Implantation in Patients with Impaired Renal Function? Open
A key factor for the success of transcatheter aortic valve implantation (TAVI) techniques is the accurate anatomical measurements of the aorta.Dimensions such as the aortic annulus diameter, perimeter, orifice area, and the distance to the…
View article: Open transcatheter aortic valve implantation on a degenerated bioprosthetic valve conduit
Open transcatheter aortic valve implantation on a degenerated bioprosthetic valve conduit Open
The degeneration of bioprosthetic aortic Conduit with hemodynamic dysfunction mostly requires a re-do surgery, which is associated with an increased perioperative risk. Considering this, an open implantation of a transcatheter aortic biopr…
View article: Rapid deployment aortic valve replacement in a minimal access setting: intermediate clinical and echocardiographic outcomes†
Rapid deployment aortic valve replacement in a minimal access setting: intermediate clinical and echocardiographic outcomes† Open
Rapid deployment aortic valve replacement can be performed safely in a minimal access setting with low complication rates and good haemodynamic results. Therefore, rapid deployment valves are a relevant option in minimal access surgery.
View article: Low-flow lower body perfusion for spinal protection in a frozen elephant trunk simulation model
Low-flow lower body perfusion for spinal protection in a frozen elephant trunk simulation model Open
The prolonged SCP provides an insufficient lumbar spinal cord protection during the FET procedure at 28°C. The use of a low-flow LBP in addition to SCP may reduce functional and structural spinal damage.
View article: Table of Contents
Table of Contents Open
View article: Simultaneous Double Valve-in-Valve TAVI Procedure for Failed Bioprostheses
Simultaneous Double Valve-in-Valve TAVI Procedure for Failed Bioprostheses Open