Peter J. Davis
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View article: Abstract 152: Predictors of Endovascular Supply Cost in Aspiration Thrombectomy
Abstract 152: Predictors of Endovascular Supply Cost in Aspiration Thrombectomy Open
Introduction/Purpose Large‐vessel occlusion ischemic stroke causes significant morbidity and mortality, with stroke accounting for $2 trillion of losses globally each year. Mechanical thrombectomy has proven to have robust outcomes but inv…
View article: High-flow nasal cannula therapy versus continuous positive airway pressure for non-invasive respiratory support in paediatric critical care: the FIRST-ABC RCTs
High-flow nasal cannula therapy versus continuous positive airway pressure for non-invasive respiratory support in paediatric critical care: the FIRST-ABC RCTs Open
Background Despite the increasing use of non-invasive respiratory support in paediatric intensive care units, there are no large randomised controlled trials comparing two commonly used non-invasive respiratory support modes, continuous po…
View article: Transition from neonatal to paediatric intensive care of very preterm-born children: a cohort study of children born between 2013 and 2018 in England and Wales
Transition from neonatal to paediatric intensive care of very preterm-born children: a cohort study of children born between 2013 and 2018 in England and Wales Open
Objective Following very preterm birth, some children require ongoing intensive care after the neonatal period and transition directly from neonatal units (NNUs) to paediatric intensive care units (PICUs) around term-corrected age. We aime…
View article: Cost-effectiveness of high flow nasal cannula therapy versus continuous positive airway pressure for non-invasive respiratory support in paediatric critical care
Cost-effectiveness of high flow nasal cannula therapy versus continuous positive airway pressure for non-invasive respiratory support in paediatric critical care Open
Background High flow nasal cannula therapy (HFNC) and continuous positive airway pressure (CPAP) are two widely used modes of non-invasive respiratory support in paediatric critical care units. The FIRST-ABC randomised controlled trials (R…
View article: Timing of Neonatal Discharge and Unplanned Readmission to PICUs Among Infants Born Preterm
Timing of Neonatal Discharge and Unplanned Readmission to PICUs Among Infants Born Preterm Open
Importance Children born very preterm (<32 weeks) are at risk of ongoing morbidity and admission to pediatric intensive care units (PICUs) in childhood. However, the influence of the timing of neonatal discharge on unplanned PICU ad…
View article: Risk factors and early outcomes associated with prolonged pleural effusion/chylothorax after paediatric cardiac surgery
Risk factors and early outcomes associated with prolonged pleural effusion/chylothorax after paediatric cardiac surgery Open
OBJECTIVES Prolonged pleural effusion/chylothorax (PPE/C) is a less investigated complication following paediatric cardiac surgery, and its true incidence, risk factors and impact on postoperative outcomes are not well described. We aim to…
View article: Construction of a decision model for donor testing in cases of suspected antibody‐mediated transfusion‐related‐acute‐lung‐injury
Construction of a decision model for donor testing in cases of suspected antibody‐mediated transfusion‐related‐acute‐lung‐injury Open
Objective To propose a rational basis for donor testing in cases of suspected antibody‐mediated transfusion‐related lung injury (AMT). Background Anti‐leukocyte antibodies in donated blood are established causes of transfusion‐related lung…
View article: Characteristics of children requiring admission to neonatal care and paediatric intensive care before the age of 2 years in England and Wales: a data linkage study
Characteristics of children requiring admission to neonatal care and paediatric intensive care before the age of 2 years in England and Wales: a data linkage study Open
Objective To quantify the characteristics of children admitted to neonatal units (NNUs) and paediatric intensive care units (PICUs) before the age of 2 years. Design A data linkage study of routinely collected data. Setting National Health…
View article: Abraham's Pictures - a novel
Abraham's Pictures - a novel Open
This thesis is in two parts. Part A is a novel titled Abraham’s Pictures. It reveals the story ofAbraham Rosen, a writer and photographer in current day Melbourne seeking to come toterms with a prediction, made on his fiftieth birthday, th…
View article: Conservative versus liberal oxygenation targets in critically ill children (Oxy-PICU): a UK multicentre, open, parallel-group, randomised clinical trial
Conservative versus liberal oxygenation targets in critically ill children (Oxy-PICU): a UK multicentre, open, parallel-group, randomised clinical trial Open
UK National Institute for Health and Care Research Health Technology Assessment Programme.
View article: Paediatric intensive care admissions of preterm children born <32 weeks gestation: a national retrospective cohort study using data linkage
Paediatric intensive care admissions of preterm children born <32 weeks gestation: a national retrospective cohort study using data linkage Open
Objective Survival of babies born very preterm (<32 weeks gestational age) has increased, although preterm-born children may have ongoing morbidity. We aimed to investigate the risk of admission to paediatric intensive care units (PICUs) o…
View article: Increased reports of severe myocarditis associated with enterovirus infection in neonates, United Kingdom, 27 June 2022 to 26 April 2023
Increased reports of severe myocarditis associated with enterovirus infection in neonates, United Kingdom, 27 June 2022 to 26 April 2023 Open
Enteroviruses are a common cause of seasonal childhood infections. The vast majority of enterovirus infections are mild and self-limiting, although neonates can sometimes develop severe disease. Myocarditis is a rare complication of entero…
View article: Pediatric Hospitalizations and ICU Admissions Due to COVID-19 and Pediatric Inflammatory Multisystem Syndrome Temporally Associated With SARS-CoV-2 in England
Pediatric Hospitalizations and ICU Admissions Due to COVID-19 and Pediatric Inflammatory Multisystem Syndrome Temporally Associated With SARS-CoV-2 in England Open
Importance Investigating how the risk of serious illness after SARS-CoV-2 infection in children and adolescents has changed as new variants have emerged is essential to inform public health interventions and clinical guidance. Objective To…
View article: Understanding the co‐construction of safety in the paediatric intensive care unit: A meta‐ethnography of parents' experiences
Understanding the co‐construction of safety in the paediatric intensive care unit: A meta‐ethnography of parents' experiences Open
Background Children experiencing critical illness or injury may require admission to a paediatric intensive care unit (PICU) to receive life‐sustaining or life‐saving treatment. Studies have explored the experience of parents with a child …
View article: Good clinical research practice (<scp>GCRP</scp>) in pharmacodynamic studies of neuromuscular blocking agents <scp>III</scp>: The 2023 Geneva revision
Good clinical research practice (<span>GCRP</span>) in pharmacodynamic studies of neuromuscular blocking agents <span>III</span>: The 2023 Geneva revision Open
The set of guidelines for good clinical research practice in pharmacodynamic studies of neuromuscular blocking agents was developed following an international consensus conference in Copenhagen in 1996 (Viby‐Mogensen et al., Acta Anaesthes…
View article: Effect of High-Flow Nasal Cannula Therapy vs Continuous Positive Airway Pressure Therapy on Liberation From Respiratory Support in Acutely Ill Children Admitted to Pediatric Critical Care Units
Effect of High-Flow Nasal Cannula Therapy vs Continuous Positive Airway Pressure Therapy on Liberation From Respiratory Support in Acutely Ill Children Admitted to Pediatric Critical Care Units Open
ISRCTN.org Identifier: ISRCTN60048867.
View article: Effect of High-Flow Nasal Cannula Therapy vs Continuous Positive Airway Pressure Following Extubation on Liberation From Respiratory Support in Critically Ill Children
Effect of High-Flow Nasal Cannula Therapy vs Continuous Positive Airway Pressure Following Extubation on Liberation From Respiratory Support in Critically Ill Children Open
isrctn.org Identifier: ISRCTN60048867.
View article: 1756 Paediatric rapid reviews – do they enable timely patient review and appropriate escalation in a tertiary paediatric hospital?
1756 Paediatric rapid reviews – do they enable timely patient review and appropriate escalation in a tertiary paediatric hospital? Open
Background Rapid reviews (RRs) and safety huddles were introduced in a tertiary children's hospital in 2017 in order to improve the rapid assessment and expectant management of unwell patients across the hospital and prevent unrecognised d…
View article: Learning lessons from the paediatric critical care response to the SARS-CoV-2 pandemic in England and Wales: a qualitative study
Learning lessons from the paediatric critical care response to the SARS-CoV-2 pandemic in England and Wales: a qualitative study Open
Objectives To explore the experiences of clinical leads in paediatric critical care units (PCCUs) in England and Wales during the reorganisation of services in the initial surge of the SARS-CoV-2 pandemic and to learn lessons for future su…
View article: A Rapid Olfactory Test as a Potential Screening Tool for COVID-19
A Rapid Olfactory Test as a Potential Screening Tool for COVID-19 Open
This prospective study assesses the feasibility of a novel, objective olfactory test as part of an initial screening for COVID-19 in adults with unknown disease status.
View article: Deaths in Children and Young People in England following SARS-CoV-2 infection during the first pandemic year: a national study using linked mandatory child death reporting data
Deaths in Children and Young People in England following SARS-CoV-2 infection during the first pandemic year: a national study using linked mandatory child death reporting data Open
Background Deaths in children and young people (CYP) following SARS-CoV-2 infection are rare. Quantifying the risk of mortality is challenging because of high relative prevalence of asymptomatic and non-specific disease manifestations. The…
View article: Which children and young people are at higher risk of severe disease and death after SARS-CoV-2 infection: a systematic review and individual patient meta-analysis
Which children and young people are at higher risk of severe disease and death after SARS-CoV-2 infection: a systematic review and individual patient meta-analysis Open
Background We aimed to use individual patient data to describe pre-existing factors associated with severe disease, primarily admission to critical care, and death secondary to SARS-CoV-2 infection in children and young people (CYP) in hos…