Peter J. Psaltis
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View article: Real-World Uptake of Intravascular Imaging for Percutaneous Coronary Intervention: From Exception to Everyday Practice
Real-World Uptake of Intravascular Imaging for Percutaneous Coronary Intervention: From Exception to Everyday Practice Open
View article: Cardiovascular-Kidney-Metabolic Syndrome: Rethinking Risk, Redefining Care
Cardiovascular-Kidney-Metabolic Syndrome: Rethinking Risk, Redefining Care Open
View article: Coronary Inflammation in Patients With and Without Standard Modifiable Cardiovascular Risk Factors: Insights From a Novel Computed Tomography Imaging Biomarker Pericoronary Adipose Tissue Attenuation
Coronary Inflammation in Patients With and Without Standard Modifiable Cardiovascular Risk Factors: Insights From a Novel Computed Tomography Imaging Biomarker Pericoronary Adipose Tissue Attenuation Open
In patients undergoing clinically indicated CTCA, patients without SMuRFs exhibited a similar degree of coronary inflammation to those with SMuRFs, despite having a lower plaque burden and stenosis severity. These findings may provide earl…
View article: Persistent inflammation after myocardial infarction: elevated IL-6 associates with impaired coronary plaque stabilization despite optimal therapy
Persistent inflammation after myocardial infarction: elevated IL-6 associates with impaired coronary plaque stabilization despite optimal therapy Open
View article: Prevalence of Overweight and Obesity Among Patients Admitted With Acute Coronary Syndromes: Implications for Semaglutide Eligibility to Further Reduce Residual Risk
Prevalence of Overweight and Obesity Among Patients Admitted With Acute Coronary Syndromes: Implications for Semaglutide Eligibility to Further Reduce Residual Risk Open
View article: Type 2 Diabetes and Acute Myocardial Infarction: Admission Complexity and Readmission Rates
Type 2 Diabetes and Acute Myocardial Infarction: Admission Complexity and Readmission Rates Open
View article: Theranostic porphyrin nanoparticles identify atherosclerosis via multimodal imaging and elicit atheroprotective effects
Theranostic porphyrin nanoparticles identify atherosclerosis via multimodal imaging and elicit atheroprotective effects Open
View article: Colchicine in Atherosclerotic Cardiovascular Disease – Weighing up the evidence so far
Colchicine in Atherosclerotic Cardiovascular Disease – Weighing up the evidence so far Open
View article: Functional Coronary Angiography for the Diagnosis of Coronary Vasomotor Disorders
Functional Coronary Angiography for the Diagnosis of Coronary Vasomotor Disorders Open
Microvascular and/or vasospastic angina are two common forms of coronary vasomotor disorders that may occur in patients with ischaemia and non-obstructed coronary arteries (INOCA) or myocardial infarction with non-obstructive coronary arte…
View article: Upfront Combination Therapy for LDL-C Lowering in Acute Coronary Syndrome: The Rule Rather than the Exception?
Upfront Combination Therapy for LDL-C Lowering in Acute Coronary Syndrome: The Rule Rather than the Exception? Open
View article: The emerging role of glycans and the importance of sialylation in cardiovascular disease
The emerging role of glycans and the importance of sialylation in cardiovascular disease Open
Glycosylation is the process by which glycans (i.e. 'sugars') are enzymatically attached to proteins or lipids to form glycoconjugates. Growing evidence points to glycosylation playing a central role in atherosclerosis. Glycosylation occur…
View article: 3D-printed micro-axicon enables extended depth-of-focus intravascular optical coherence tomography in vivo
3D-printed micro-axicon enables extended depth-of-focus intravascular optical coherence tomography in vivo Open
View article: Achieved levels of apolipoprotein B and plaque composition after acute coronary syndromes: Insights from HUYGENS
Achieved levels of apolipoprotein B and plaque composition after acute coronary syndromes: Insights from HUYGENS Open
NCT03570697.
View article: Computer-Assisted Protocol-Adherent Blood Lipid Evaluation in Vascular Outpatients (CAPABLE-Vascular)
Computer-Assisted Protocol-Adherent Blood Lipid Evaluation in Vascular Outpatients (CAPABLE-Vascular) Open
Background: The lack of availability of test results in vascular surgery outpatient clinics impedes the medical management of vascular risk factors, such as dyslipidaemia and diabetes mellitus. This study sought to evaluate the feasibility…
View article: Syndecan-1, Endocan and Non-Culprit Coronary Plaque Composition Following Non-St Elevation Myocardial Infarction
Syndecan-1, Endocan and Non-Culprit Coronary Plaque Composition Following Non-St Elevation Myocardial Infarction Open
View article: Editorial: Role of colchicine in atherosclerosis
Editorial: Role of colchicine in atherosclerosis Open
View article: High-Sensitivity Cardiac Troponin T Reporting, Clinical Outcomes, and Health Care Resource Use
High-Sensitivity Cardiac Troponin T Reporting, Clinical Outcomes, and Health Care Resource Use Open
Importance Despite being recommended by clinical guidelines, substantial concerns remain regarding the use of high-sensitivity cardiac troponin assays and whether it is associated with increased resource use, myocardial infarction (MI) or …
View article: Advances in the Computational Assessment of Disturbed Coronary Flow and Wall Shear Stress: A Contemporary Review
Advances in the Computational Assessment of Disturbed Coronary Flow and Wall Shear Stress: A Contemporary Review Open
Coronary artery blood flow is influenced by various factors including vessel geometry, hemodynamic conditions, timing in the cardiac cycle, and rheological conditions. Multiple patterns of disturbed coronary flow may occur when blood flow …
View article: Improving Cardiovascular Disease Prediction With Machine Learning Using Mental Health Data
Improving Cardiovascular Disease Prediction With Machine Learning Using Mental Health Data Open
View article: Optical coherence tomography assessment of the impact of colchicine on non-culprit coronary plaque composition after myocardial infarction
Optical coherence tomography assessment of the impact of colchicine on non-culprit coronary plaque composition after myocardial infarction Open
Aims Low-dose colchicine reduces the risk of cardiovascular events after myocardial infarction (MI). The purpose of this study was to assess the effect of colchicine post-MI on coronary plaque morphology in non-culprit segments by optical …
View article: Reconstituted high-density lipoproteins rescue diabetes-impaired endothelial cell metabolic reprograming and angiogenic responses to hypoxia
Reconstituted high-density lipoproteins rescue diabetes-impaired endothelial cell metabolic reprograming and angiogenic responses to hypoxia Open
Objective: Impaired angiogenic responses to ischemia underlie diabetic vascular complications. Reconstituted high-density lipoproteins (rHDL) have proangiogenic effects in diabetes. The pyruvate dehydrogenase kinase 4 (PDK4)/pyruvate dehyd…
View article: Prevalence and burden of coronary artery disease on computed tomography coronary angiography and its correlation with high-density lipoprotein in the Northern Territory, Australia
Prevalence and burden of coronary artery disease on computed tomography coronary angiography and its correlation with high-density lipoprotein in the Northern Territory, Australia Open
Indigenous Australians are known to have a higher prevalence of coronary artery disease (CAD) than non-Indigenous counterparts. Atherogenic lipid profiles, characterised by low serum levels of high-density lipoprotein (HDL) and higher seru…
View article: 3D-printed axicon enables extended depth-of-focus intravascular optical coherence tomography
3D-printed axicon enables extended depth-of-focus intravascular optical coherence tomography Open
A fundamental challenge in endoscopy is how to fabricate a small fiber-optic probe that can achieve comparable function to probes with large, complicated optics (e.g., high resolution and extended depth of focus). To achieve high resolutio…
View article: Evaluating the severity of tandem coronary stenoses: Insights from simulated FFR and iFR techniques
Evaluating the severity of tandem coronary stenoses: Insights from simulated FFR and iFR techniques Open
Aims: The presence of coronary tandem lesions poses a significant challenge for the accurate diagnosis and management of coronary artery diseases. This study set out to provide a deeper understanding of the haemodynamic interactions betwee…
View article: Protocol and rationale of the Australian multicentre registry for serial cardiac computed tomography angiography (ARISTOCRAT): a prospective observational study of the natural history of pericoronary adipose tissue attenuation and radiomics
Protocol and rationale of the Australian multicentre registry for serial cardiac computed tomography angiography (ARISTOCRAT): a prospective observational study of the natural history of pericoronary adipose tissue attenuation and radiomics Open
This study has been prospectively registered with the Australia and New Zealand Clinical Trials Registry (ACTRN12621001018808).
View article: Incidence of thrombocytopenia-associated cerebral venous sinus thrombosis: a population-based study
Incidence of thrombocytopenia-associated cerebral venous sinus thrombosis: a population-based study Open
Objectives The identification of SARS-CoV-2 vaccine-induced immune thrombotic thrombocytopenia (VITT) followed the recognition of a hitherto uncommon clinical syndrome frequently associated with cerebral venous sinus thrombosis (CVST), ter…
View article: TRIM2 Selectively Regulates Inflammation-Driven Pathological Angiogenesis without Affecting Physiological Hypoxia-Mediated Angiogenesis
TRIM2 Selectively Regulates Inflammation-Driven Pathological Angiogenesis without Affecting Physiological Hypoxia-Mediated Angiogenesis Open
Angiogenesis is a critical physiological response to ischemia but becomes pathological when dysregulated and driven excessively by inflammation. We recently identified a novel angiogenic role for tripartite-motif-containing protein 2 (TRIM…
View article: Multifunctional biomimetic porphyrin-lipid nanoparticles – novel nanoscale theranostics for atherosclerotic cardiovascular disease
Multifunctional biomimetic porphyrin-lipid nanoparticles – novel nanoscale theranostics for atherosclerotic cardiovascular disease Open
Background High-density lipoprotein (HDL) nanoagents have unrealized potential for atherosclerosis theranostics. Porphyrin-lipid HDL mimetic nanoparticles (Por-HDL-NPs) incorporate porphyrin-lipid which permits near infrared fluorescence i…
View article: Psoas Muscle Area as a Predictor of Transcatheter Aortic Valve Implantation Outcomes
Psoas Muscle Area as a Predictor of Transcatheter Aortic Valve Implantation Outcomes Open
A low PMA is associated with increased length of hospital stay in female TAVI patients but does not provide additional predictive value over traditional frailty scores. The PMA was not shown to correlate with TAVI-related complications or …
View article: Clinical Pathway for Coronary Atherosclerosis in Patients Without Conventional Modifiable Risk Factors
Clinical Pathway for Coronary Atherosclerosis in Patients Without Conventional Modifiable Risk Factors Open
Reducing the incidence and prevalence of standard modifiable cardiovascular risk factors (SMuRFs) is critical to tackling the global burden of coronary artery disease (CAD). However, a substantial number of individuals develop coronary ath…