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View article: Effect of ferrite content and temperature on the magnetic properties of Fe@SiO2@Mn-Zn-ferrite SMC materials.
Effect of ferrite content and temperature on the magnetic properties of Fe@SiO2@Mn-Zn-ferrite SMC materials. Open
Building upon previous studies that have reported promising soft magnetic performance of Fe/Mn-Zn ferrite-based soft magnetic composites (SMCs), the present work focuses on effect of ferrite content and temperature on the magnetic properti…
View article: Anisotropy of losses in non-segmented assemblies of grain-oriented steel with circular easy axis distribution
Anisotropy of losses in non-segmented assemblies of grain-oriented steel with circular easy axis distribution Open
This study explores the frequency-dependent magnetic losses in grain-oriented non-segmented cores with layers shifted by a constant angle, creating a circular distribution of easy axes across the core, up to 500 Hz. This innovative approac…
View article: Interpersonal and Organizational Dimensions of Leaders’ Transformational Behaviours Measured by LPI©
Interpersonal and Organizational Dimensions of Leaders’ Transformational Behaviours Measured by LPI© Open
This paper discusses characteristics of leaders’ transformational behaviours by using the five-factor Exemplary Leadership model measured by Leadership Practices Inventory (LPI©) (Kouzes & Posner, 2002). Literature is scarce on investigati…
View article: Effects of particle surface modification on magnetic behavior of soft magnetic Fe@SiO2 composites and Fe compacts
Effects of particle surface modification on magnetic behavior of soft magnetic Fe@SiO2 composites and Fe compacts Open
The study aims to evaluate the influence of surface modification of Fe powder on the magnetic behavior of soft magnetic compacts and composites that can possibly enhance their properties. The smoothing of ferromagnetic particle surfaces le…
View article: Machine learning assisted optimization of soft magnetic properties in ternary Fe–Si–Al alloys
Machine learning assisted optimization of soft magnetic properties in ternary Fe–Si–Al alloys Open
The transition from the traditional “post-analysis” strategy for developing soft magnetic materials to an innovative “pre-design” one is highly desirable for the development of advanced electrical devices. In this work, we present the crea…
View article: Exploring the Impact of Different Milling Parameters of Fe/SiO2 Composites on Their Structural and Magnetic Properties
Exploring the Impact of Different Milling Parameters of Fe/SiO2 Composites on Their Structural and Magnetic Properties Open
This research focuses on the production process of soft magnetic composites in the form of 3D bulk compacts made from insulated powder particles using different milling parameters, aiming to enhance their magnetic properties and to study a…
View article: Wide induction range analysis of DC magnetic properties and magnetization processes of Fe-based soft magnetic composites
Wide induction range analysis of DC magnetic properties and magnetization processes of Fe-based soft magnetic composites Open
The paper presents systematic analyses of a wide maximum induction range (0.001 T–1.4 T) DC magnetic properties of iron-based soft magnetic composite (SMC) materials by applying different methods to understand the specific features of magn…
View article: Supplementary Methods from Synthesis and Profiling of a Novel Potent Selective Inhibitor of CHK1 Kinase Possessing Unusual N-trifluoromethylpyrazole Pharmacophore Resistant to Metabolic N-dealkylation
Supplementary Methods from Synthesis and Profiling of a Novel Potent Selective Inhibitor of CHK1 Kinase Possessing Unusual N-trifluoromethylpyrazole Pharmacophore Resistant to Metabolic N-dealkylation Open
Detail description of Material and Methods
View article: Supplementary Methods from Synthesis and Profiling of a Novel Potent Selective Inhibitor of CHK1 Kinase Possessing Unusual N-trifluoromethylpyrazole Pharmacophore Resistant to Metabolic N-dealkylation
Supplementary Methods from Synthesis and Profiling of a Novel Potent Selective Inhibitor of CHK1 Kinase Possessing Unusual N-trifluoromethylpyrazole Pharmacophore Resistant to Metabolic N-dealkylation Open
Detail description of Material and Methods
View article: Data from Synthesis and Profiling of a Novel Potent Selective Inhibitor of CHK1 Kinase Possessing Unusual N-trifluoromethylpyrazole Pharmacophore Resistant to Metabolic N-dealkylation
Data from Synthesis and Profiling of a Novel Potent Selective Inhibitor of CHK1 Kinase Possessing Unusual N-trifluoromethylpyrazole Pharmacophore Resistant to Metabolic N-dealkylation Open
Checkpoint-mediated dependency of tumor cells can be deployed to selectively kill them without substantial toxicity to normal cells. Specifically, loss of CHK1, a serine threonine kinase involved in the surveillance of the G2–M checkpoint …
View article: Data from Synthesis and Profiling of a Novel Potent Selective Inhibitor of CHK1 Kinase Possessing Unusual N-trifluoromethylpyrazole Pharmacophore Resistant to Metabolic N-dealkylation
Data from Synthesis and Profiling of a Novel Potent Selective Inhibitor of CHK1 Kinase Possessing Unusual N-trifluoromethylpyrazole Pharmacophore Resistant to Metabolic N-dealkylation Open
Checkpoint-mediated dependency of tumor cells can be deployed to selectively kill them without substantial toxicity to normal cells. Specifically, loss of CHK1, a serine threonine kinase involved in the surveillance of the G2–M checkpoint …
View article: Supplemetary Tables from Synthesis and Profiling of a Novel Potent Selective Inhibitor of CHK1 Kinase Possessing Unusual N-trifluoromethylpyrazole Pharmacophore Resistant to Metabolic N-dealkylation
Supplemetary Tables from Synthesis and Profiling of a Novel Potent Selective Inhibitor of CHK1 Kinase Possessing Unusual N-trifluoromethylpyrazole Pharmacophore Resistant to Metabolic N-dealkylation Open
Table S1. Mouse plasma protein binding profile of MU380 and SCH900776. Table S2. IC50 determination of main P450 cytochrome isoforms in human liver microsomes. Table S3. A) Evaluation of MU380 and SCH900776 disappearance with time in the p…
View article: Supplementary file-Synthesis from Synthesis and Profiling of a Novel Potent Selective Inhibitor of CHK1 Kinase Possessing Unusual N-trifluoromethylpyrazole Pharmacophore Resistant to Metabolic N-dealkylation
Supplementary file-Synthesis from Synthesis and Profiling of a Novel Potent Selective Inhibitor of CHK1 Kinase Possessing Unusual N-trifluoromethylpyrazole Pharmacophore Resistant to Metabolic N-dealkylation Open
Detail description of synthesis and supporting data
View article: Supplementary Legends from Synthesis and Profiling of a Novel Potent Selective Inhibitor of CHK1 Kinase Possessing Unusual N-trifluoromethylpyrazole Pharmacophore Resistant to Metabolic N-dealkylation
Supplementary Legends from Synthesis and Profiling of a Novel Potent Selective Inhibitor of CHK1 Kinase Possessing Unusual N-trifluoromethylpyrazole Pharmacophore Resistant to Metabolic N-dealkylation Open
Supplementary Legends for Supplemetary Figure S1 - S11
View article: Supplemetary Tables from Synthesis and Profiling of a Novel Potent Selective Inhibitor of CHK1 Kinase Possessing Unusual N-trifluoromethylpyrazole Pharmacophore Resistant to Metabolic N-dealkylation
Supplemetary Tables from Synthesis and Profiling of a Novel Potent Selective Inhibitor of CHK1 Kinase Possessing Unusual N-trifluoromethylpyrazole Pharmacophore Resistant to Metabolic N-dealkylation Open
Table S1. Mouse plasma protein binding profile of MU380 and SCH900776. Table S2. IC50 determination of main P450 cytochrome isoforms in human liver microsomes. Table S3. A) Evaluation of MU380 and SCH900776 disappearance with time in the p…
View article: Supplementary Figures from Synthesis and Profiling of a Novel Potent Selective Inhibitor of CHK1 Kinase Possessing Unusual N-trifluoromethylpyrazole Pharmacophore Resistant to Metabolic N-dealkylation
Supplementary Figures from Synthesis and Profiling of a Novel Potent Selective Inhibitor of CHK1 Kinase Possessing Unusual N-trifluoromethylpyrazole Pharmacophore Resistant to Metabolic N-dealkylation Open
Figure S1. In vitro profiling of SCH900776 and its selected analogs. Figure S2. Analogs of MU380 with the N-trifluoromethylpyrazol pharmacophore. Figure S3. Dot plots of flow cytometric analysis using γH2AX and Annexin V staining related …
View article: Supplementary Figures from Synthesis and Profiling of a Novel Potent Selective Inhibitor of CHK1 Kinase Possessing Unusual N-trifluoromethylpyrazole Pharmacophore Resistant to Metabolic N-dealkylation
Supplementary Figures from Synthesis and Profiling of a Novel Potent Selective Inhibitor of CHK1 Kinase Possessing Unusual N-trifluoromethylpyrazole Pharmacophore Resistant to Metabolic N-dealkylation Open
Figure S1. In vitro profiling of SCH900776 and its selected analogs. Figure S2. Analogs of MU380 with the N-trifluoromethylpyrazol pharmacophore. Figure S3. Dot plots of flow cytometric analysis using γH2AX and Annexin V staining related …
View article: Supplementary Legends from Synthesis and Profiling of a Novel Potent Selective Inhibitor of CHK1 Kinase Possessing Unusual N-trifluoromethylpyrazole Pharmacophore Resistant to Metabolic N-dealkylation
Supplementary Legends from Synthesis and Profiling of a Novel Potent Selective Inhibitor of CHK1 Kinase Possessing Unusual N-trifluoromethylpyrazole Pharmacophore Resistant to Metabolic N-dealkylation Open
Supplementary Legends for Supplemetary Figure S1 - S11
View article: Supplementary file-Synthesis from Synthesis and Profiling of a Novel Potent Selective Inhibitor of CHK1 Kinase Possessing Unusual N-trifluoromethylpyrazole Pharmacophore Resistant to Metabolic N-dealkylation
Supplementary file-Synthesis from Synthesis and Profiling of a Novel Potent Selective Inhibitor of CHK1 Kinase Possessing Unusual N-trifluoromethylpyrazole Pharmacophore Resistant to Metabolic N-dealkylation Open
Detail description of synthesis and supporting data
View article: Effect of Rare-Earth Doping on Dynamic Magnetic Properties of FeGa Alloy
Effect of Rare-Earth Doping on Dynamic Magnetic Properties of FeGa Alloy Open
The magnetization process at elevated frequencies (up to 15 kHz) of ring-shaped binary Fe 81 Ga 19 alloy was studied. Frequency and magnetic field dependences of coercive field and remanent induction were analyzed. Hysteresis loops and ini…
View article: High pressure compaction of soft magnetic iron powder
High pressure compaction of soft magnetic iron powder Open
Iron is the most widespread ferromagnetic used in soft magnetic composites. Ferromagnetic powders are usually pressed at relatively high pressure to the required shape before heat treatment. The functional properties of soft magnetic mater…
View article: Impact of the Surface Irregularities of NiFeMo Compacted Powder Particles on Irreversible Magnetization Processes
Impact of the Surface Irregularities of NiFeMo Compacted Powder Particles on Irreversible Magnetization Processes Open
One specific group of materials with excellent application potential are powder-compacted soft magnetic materials. These materials have been intensively studied by materials scientists to improve their magnetic properties. This work descri…
View article: Relationship between Cultural Origin of Multinational Companies and Employing Expatriates in Foreign Subsidiaries in Central and Eastern Europe
Relationship between Cultural Origin of Multinational Companies and Employing Expatriates in Foreign Subsidiaries in Central and Eastern Europe Open
In the present study, we examine the question of whether the cultural characteristics of the country of the parent company are related to the posting practices of the parent company. According to our hypothesis, the management culture of t…
View article: Correlation between Cutting Clearance, Deformation Texture, and Magnetic Loss Prediction in Non-Oriented Electrical Steels
Correlation between Cutting Clearance, Deformation Texture, and Magnetic Loss Prediction in Non-Oriented Electrical Steels Open
Manufacturing the magnetic cores in electrical machines impacts the magnetic performance of the electrical steel by inducing stresses near the cutting edge. In this paper, energy loss behaviour in non-oriented electrical steels punched wit…
View article: Analysis of Magnetic Properties of Iron-Resin-Ferrite Soft Magnetic Composite Materials
Analysis of Magnetic Properties of Iron-Resin-Ferrite Soft Magnetic Composite Materials Open
The analysis of magnetic properties of soft magnetic composite materials composed of iron insulated by polymer bonded Ni-Zn ferrite nanofibers is presented in the paper, focusing on the investigation of magnetization processes, by means of…