Peter Kronen
YOU?
Author Swipe
View article: Normative Values of Brainstem Auditory-Evoked Responses in Sheep
Normative Values of Brainstem Auditory-Evoked Responses in Sheep Open
Background: The brainstem auditory-evoked response (BAER) is an established electrophysiological measure of neural activity from the auditory nerve up to the brain stem. The BAER is used to diagnose abnormalities in auditory pathways and i…
View article: Effects of shape and structure of a new 3D-printed personalized bioresorbable tracheal stent on fit and biocompatibility in a rabbit model
Effects of shape and structure of a new 3D-printed personalized bioresorbable tracheal stent on fit and biocompatibility in a rabbit model Open
To date, several types of airway stents are available to treat central airway obstructions. However, the ideal stent that can overcome anatomical, mechanical and microbiological issues is still awaited. In addition, therapeutic effect and …
View article: Haptoglobin attenuates cerebrospinal fluid hemoglobin-induced neurological deterioration in sheep
Haptoglobin attenuates cerebrospinal fluid hemoglobin-induced neurological deterioration in sheep Open
Background Secondary brain injury (SBI) occurs with a lag of several days post-bleeding in patients with aneurysmal subarachnoid hemorrhage (aSAH) and is a strong contributor to mortality and long-term morbidity. aSAH-SBI coincides with ce…
View article: Haptoglobin attenuates cerebrospinal fluid hemoglobin-induced neurological deterioration in sheep
Haptoglobin attenuates cerebrospinal fluid hemoglobin-induced neurological deterioration in sheep Open
Background Secondary brain injury (SBI) occurs with a lag of several days post-bleeding in patients with aneurysmal subarachnoid hemorrhage (aSAH) and is a strong contributor to mortality and long-term morbidity. aSAH-SBI coincides with ce…
View article: Combined electric and magnetic field therapy enhances bone repair and regeneration in two tibia osteotomy models in sheep.
Combined electric and magnetic field therapy enhances bone repair and regeneration in two tibia osteotomy models in sheep. Open
Background: Therapies using electromagnetic field technology show evidence of enhanced bone regeneration at the fracture site, potentially preventing delayed or non-unions. Methods: Combined electric and magnetic field (CEMF) treatment was…
View article: Blood oxygenation-level dependent cerebrovascular reactivity imaging as strategy to monitor CSF-hemoglobin toxicity
Blood oxygenation-level dependent cerebrovascular reactivity imaging as strategy to monitor CSF-hemoglobin toxicity Open
It is demonstrated that CSF-Hb toxicity leads to rapid cerebrovascular reactivity impairment, which is blunted by haptoglobin co-infusion. BOLD-CVR may therefore be further evaluated as a monitoring strategy for CSF-Hb toxicity after aSAH.
View article: Blood oxygenation-level dependent cerebrovascular reactivity imaging as strategy to monitor CSF-hemoglobin toxicity
Blood oxygenation-level dependent cerebrovascular reactivity imaging as strategy to monitor CSF-hemoglobin toxicity Open
PurposeCell-free hemoglobin in the cerebrospinal fluid (CSF-Hb) may be one of the main drivers of secondary brain injury after aneurysmal subarachnoid hemorrhage (aSAH). Haptoglobin scavenging of CSF-Hb has been shown to mitigate cerebrova…
View article: Blood oxygenation-level dependent cerebrovascular reactivity imaging as strategy to monitor CSF-hemoglobin toxicity
Blood oxygenation-level dependent cerebrovascular reactivity imaging as strategy to monitor CSF-hemoglobin toxicity Open
Purpose Cell-free hemoglobin in the cerebrospinal fluid (CSF-Hb) may be one of the main drivers of secondary brain injury after aneurysmal subarachnoid hemorrhage. Haptoglobin scavenging of CSF-Hb has been shown to mitigate cerebrovascular…
View article: Multilingual validation of the short form of the Unesp-Botucatu Feline Pain Scale (UFEPS-SF)
Multilingual validation of the short form of the Unesp-Botucatu Feline Pain Scale (UFEPS-SF) Open
Background Pain is the leading cause of animal suffering, hence the importance of validated tools to ensure its appropriate evaluation and treatment. We aimed to test the psychometric properties of the short form of the Unesp-Botucatu Feli…
View article: Industrial Development of Standardized Fetal Progenitor Cell Therapy for Tendon Regenerative Medicine: Preliminary Safety in Xenogeneic Transplantation
Industrial Development of Standardized Fetal Progenitor Cell Therapy for Tendon Regenerative Medicine: Preliminary Safety in Xenogeneic Transplantation Open
Tendon defects require multimodal therapeutic management over extensive periods and incur high collateral burden with frequent functional losses. Specific cell therapies have recently been developed in parallel to surgical techniques for m…
View article: Digital light 3D printing of customized bioresorbable airway stents with elastomeric properties
Digital light 3D printing of customized bioresorbable airway stents with elastomeric properties Open
Customized bioresorbable airway stents with elasticity similar to silicone were 3D printed by digital light processing.
View article: MRI-guided, transrectal, intraprostatic steam application as potential focal therapeutic modality for prostatic diseases in a large animal translational model: A feasibility follow-up study
MRI-guided, transrectal, intraprostatic steam application as potential focal therapeutic modality for prostatic diseases in a large animal translational model: A feasibility follow-up study Open
Parallel to establishment of diagnostic surveillance protocols for detection of prostatic diseases, novel treatment strategies should be developed. The aim of the present study is to evaluate the feasibility and possible side effects of tr…
View article: Intraperitoneal and incisional analgesia in small animals: simple, cost‐effective techniques
Intraperitoneal and incisional analgesia in small animals: simple, cost‐effective techniques Open
The World Small Animal Veterinary Association Global Pain Council (WSAVA‐GPC) has recently published its first “capsule review” by Monteiro et al . These are short articles that present a brief assessment of the scientific evidence and pra…
View article: Haptoglobin administration into the subarachnoid space prevents hemoglobin-induced cerebral vasospasm
Haptoglobin administration into the subarachnoid space prevents hemoglobin-induced cerebral vasospasm Open
Delayed ischemic neurological deficit (DIND) is a major driver of adverse outcomes in patients with aneurysmal subarachnoid hemorrhage (aSAH), defining an unmet need for therapeutic development. Cell-free hemoglobin that is released from e…
View article: Ligature-Induced Peri-Implantitis in Minipigs Revisited
Ligature-Induced Peri-Implantitis in Minipigs Revisited Open
Aim: The ligature-induced defect model still remains the model of first choice to experimentally investigate the cause, effect and treatment approaches of periimplantitis. It was the aim of the present in-vivo trail to revisit the ligature…
View article: Dynamization at the Near Cortex in Locking Plate Osteosynthesis by Means of Dynamic Locking Screws
Dynamization at the Near Cortex in Locking Plate Osteosynthesis by Means of Dynamic Locking Screws Open
Controlled micromotion and nearly homogeneous interfragmentary strain at the fracture site, together with the stable bicortical fixation achieved by the new dynamic locking screw, led to more uniform callus formation, significantly more ca…